Devices used for photobiomodulation of the brain-a comprehensive and systematic review.

A systematic review was conducted to determine the trends in devices and parameters used for brain photobiomodulation (PBM). The revised studies included clinical and cadaveric approaches, in which light stimuli were applied to the head and/or neck. PubMed, Scopus, Web of Science and Google Scholar databases were used for the systematic search. A total of 2133 records were screened, from which 97 were included in this review. The parameters that were extracted and analysed in each article were the device design, actuation area, actuation site, wavelength, mode of operation, power density, energy density, power output, energy per session and treatment time. To organize device information, 11 categories of devices were defined, according to their characteristics. The most used category of devices was laser handpieces, which relate to 21% of all devices, while 28% of the devices were not described. Studies for cognitive function and physiological characterisation are the most well defined ones and with more tangible results. There is a lack of consistency when reporting PBM studies, with several articles under defining the stimulation protocol, and a wide variety of parameters used for the same health conditions (e.g., Alzheimer's or Parkinson's disease) resulting in positive outcomes. Standardization for the report of these studies is warranted, as well as sham-controlled comparative studies to determine which parameters have the greatest effect on PBM treatments for different neurological conditions.

Corrigendum: Antibiotic susceptibility pattern of Portuguese environmental Legionella isolates.

[This corrects the article DOI: 10.3389/fcimb.2023.1141115.].

The generally recognized as safe (GRAS) microalgae Haematococcus pluvialis (wet) as a multifunctional additive for coloring and improving the organoleptic and functional properties of foods.

This work proposes the application of astaxanthin-rich H. pluvialis wet paste (HPW) as a partial substitute for wheat flour in the preparation of filloas, a dish that combines the basic ingredients of industrial bakery. The nutritional and color profile of HPW-enriched samples was evaluated by comparative analysis with a mixture of synthetic food dyes. The highest content of carotenoids (798 ± 12 µg g-1) and fatty acids (76 ± 2 mg g-1) was obtained for a filloa fortified with H. pluvialis in contrast to a non-significant dye response. Subsequently, the color stability of the fortified filloa was evaluated over time (3, 6 and 9 days), as well as its physicochemical properties and microbiological profile. As a result, HPW provided filloas with a longer shelf life, brightness (*L), and texture, in comparison with a mixture of synthetic dyes. In addition, an inhibitory effect of HPW towards mesophilic aerobic microorganisms in the food was obtained.

Antibiotic susceptibility pattern of Portuguese environmental Legionella isolates.

Introduction: Legionnaires' Disease is a pneumonia caused by Legionella spp., currently treated empirically with fluoroquinolones and macrolides. In this study, we aim to describe the antibiotic susceptibility pattern of environmental Legionella recovered in the south of Portugal. Methods: Minimal inhibitory concentration (MIC) determination of 57 Legionella isolates (10 Lp sg 1, 32, Lp sg 2-14 15 L. spp) was achieved by broth microdilution, as described by EUCAST, for azithromycin, clarithromycin, ciprofloxacin, levofloxacin, and doxycycline. Results: Fluoroquinolones were the most active antibiotic, displaying the lowest MIC values in contrast to doxycycline which had the highest. MIC90 and epidemiological cut-off (ECOFF) values were, respectively, 0.5/1 mg/L for azithromycin, 0.125/0.25 mg/L for clarithromycin, 0.064/0.125 mg/L for ciprofloxacin, 0.125/0.125 mg/L for levofloxacin and 16/32 mg/L for doxycycline. Discussion: MIC distributions were higher than reported by EUCAST for all antibiotics. Interestingly, two phenotypically resistant isolates with high-level quinolone resistance were identified. This is the first time that MIC distributions, lpeAB and tet56 genes have been investigated in Portuguese environmental isolates of Legionella.

How to choose the appropriate cannulation technique for vascular access in hemodialysis patients.

The cannulation technique is important for the survival of the arteriovenous access. Choosing the appropriate technique is a complex decision. Such choice must be customized to patients, considering their characteristics, the type of arteriovenous access and the experience of the hemodialysis team. We describe seven items that can help nurses to identify the appropriate cannulation technique: type of arteriovenous access; drainage vein; hygienic self-care profile; experience of the nursing staff in the cannulation technique and nurse-to-patient ratio; hemodialysis treatment method; patient's condition; and patient's decision. Such items can help nurses in decision-making on the "ideal" cannulation technique for each patient.

The Infidelity Scale: Psychometric properties and gender invariance among Portuguese adults

Introduction: Infidelity is a breach of trust or a crossing of the boundaries of the primary relationship and it influences intimate relationships. It can be categorised as either sexual or emotional infidelity. In Portugal, there have been few studies on this subject using suitable instruments. Objective: This study aimed to analyse the factor structure, psychometric properties, and gender invariance of the Infidelity Scale (IS) in Portuguese adults. Method: The sample comprised 660 Portuguese adults (455 women and 205 men) between 18 and 79 years of age who had been unfaithful in their relationships. Results: The confirmatory analysis showed a structure with two factors (sexual and emotional infidelity), and good values for convergent and discriminant validity were found. The results displayed a satisfactory model fit and the non-invariance of the factor structure between women and men. Conclusion: This is the first Portuguese version of the IS, an instrument for the study of intimate relationships which contributes to the development of multicultural research.

Introducción: La infidelidad es una ruptura de la confianza que influye en las relaciones íntimas. Se puede dividir en infidelidad sexual o emocional. En Portugal, hay pocos estudios sobre este tema con medidas adecuadas. Objetivo: Esta investigación tiene como objetivo analizar la estructura factorial, las propiedades psicométricas y la invariancia de género de la Escala de Infidelidad (IS) entre adultos portugueses. Método: Se aplicó el protocolo de investigación a 660 adultos portugueses (455 mujeres y 205 hombres) de entre 18 y 79 años que fueron infieles en sus relaciones. Resultados: El análisis confirmatorio mostró una estructura con dos factores (infidelidad física y emocional), y se encontraron buenos valores de validez convergente y discriminante. Los resultados mostraron un ajuste satisfactorio del modelo y la no invariabilidad de la estructura factorial entre mujeres y hombres. Conclusión: Esta es la primera versión en portugués de la IS, como medida que permite estudiar las relaciones íntimas, contribuyendo para el desarrollo de la investigación multicultural.

Improving the physicochemical properties of a traditional Portuguese cake - "económicos" with chestnut flour.

"Económicos" are traditional Portuguese pastry products; although their production is low-cost, their nutritional value is equally low. Since it is a widely consumed product in the Trás-os-Montes region, it is important to add value to it without making significant changes to the traditional recipe. Thus, this work has the main objective to increase the nutritional power of "económicos" through the incorporation of chestnut (Castanea sativa) fruit flour. The influence of the incorporation of 9% of chestnut flour as a new ingredient was analysed in terms of physical parameters (texture, colour, pH, water activity and moisture), nutritional content (according to the official AOAC methodology) and chemical parameters (sugars, fatty acids and organic acids) and the ability to control the microbial load over shelf life (32 days). Overall, the addition of the chestnut flour did not drastically change the appearance of the chemical and physical profiles of the cakes, but resulted in a lighter crumb (L*), slight changes in the texture profile, reduction of fat, and most importantly, introduced healthier flour to this inexpensive cake. Moreover, it did not stimulate the growth of microorganisms (total aerobic mesophiles, coliforms, Bacillus cereus, molds, and yeasts) during the 32 days of storage.

Radio-cephalic fistula recovered with drainage to median basilic vein by straightening of the forearm cephalic vein: A case report.

The distal arteriovenous fistula (AVF) has less complications and better patency than the proximal fistula, when it works properly. The complications of outflow of the fistula are complex, and it is necessary to analyze all solutions to solve the problem. We introduce a novel approach to solve outflow problems of a radio-cephalic AVF by straightening of the forearm cephalic vein with drainage into the median basilic vein.

Arbutus unedo leaf extracts as potential dairy preservatives: case study on quark cheese.

The plant kingdom is an endless source of molecules that can be applied in almost all realms of society. The food industry has profited from the use of plants and their derived materials for many decades. Recently, the food industry has been looking into plants to find different ways of either preserving, coloring or sweetening foods. In this work, leaf extracts of Arbutus unedo L. obtained by dynamic maceration and ultrasound assisted extraction with prior optimization of their extraction conditions through the response-surface methodology, were incorporated in quark cheese as natural preservatives and analyzed over 8 days of shelf-life. Both extracts showed antioxidant activity with no toxicity towards primary cell lines at the maximum tested concentration, as well as antibacterial activity, especially against Gram-positive strains. After their incorporation in quark cheese, no significant changes were observed in the nutritional profile and physical traits of the quark cheeses, while the microbial load was highly reduced in the cheese, especially using the extracts obtained from dynamic maceration. Thus, leaf extracts of A. unedo can be promising candidates for use in the food industry as natural preservatives.

Pott's Disease – Still an Issue in the 21st Century / El Mal de Pott: un problema que persiste en el siglo XXI

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Promising Preserving Agents from Sage and Basil: A Case Study with Yogurts.

In the present work, sage (Salvia officinalis L.) and basil (Ocimum basilicum L.) were exploited for their preservative purposes, as viable alternatives to artificial ones. The ultrasound-assisted extraction (UAE) of bioactive compounds was pre-optimized using factorial screening analysis, prior to applying response surface methodology (RSM). The obtained extracts were characterized in terms of phenolic compounds by high-performance liquid chromatography coupled to photodiode array detector and mass spectrometer HPLC-DAD-ESI/MS and bioactivities, namely the antioxidant, antimicrobial and cytotoxic potential. In addition, the most promising extracts were incorporated into yogurts, that were further screened for nutritional and physico-chemical properties and microbial load, over a shelf life of 14 days. According to the obtained results, the solvent percentage is the most relevant factor for obtaining rosmarinic acid-rich extract, followed by the extraction time and ultrasonic power. For the antioxidant and antimicrobial activity, sage showed the best result for both analysis and none of the two plant extracts were hepatotoxic. Finally, both extracts did not show changes in the physicochemical and nutritional characteristics of the yogurts and did not interfere with the growth of lactic acid bacteria, an important microorganism during yogurt fermentation. These results highlight the high potential of sage and basil as natural preservatives.

Moving Beyond Nursing Standardized Language for Substance Use Problems.

Nursing knowledge has been accompanied by the evolution of nursing standardized language systems (SLS) that can help nurses to systematize nursing care. We analyzed referential integrity (diagnosis, results, interventions) of substance related problems in Nursing SLS through documentary analysis: ICNP®, NANDA-I, Nursing Intervention Classification (NIC), Nursing Outcome Classification (NOC), NANDA NIC NOC (NNN). ICNP® has a definition of "substance abuse" but there are no clinical indicators or related factors to help formulate a diagnosis. NANDA-I does not define any related diagnosis, although it appears as related to or as a risk factor in 36 diagnoses. In NIC and NOC there are interventions and outcomes related. The phenomenon is omitted in NANDA-I and treated in a stigmatized manner by ICNP. Clear clinical indicators may be needed to help nursing diagnosis and to lead clinical reasoning.

Multiplex PCR Based Strategy for Detection of Fungal Pathogen DNA in Patients with Suspected Invasive Fungal Infections.

A new and easy polymerase chain reaction (PCR) multiplex strategy, for the identification of the most common fungal species involved in invasive fungal infections (IFI) was developed in this work. Two panels with species-specific markers were designed, the Candida Panel for the identification of Candida species, and the Filamentous Fungi Panel for the identification of Aspergillus species and Rhizopusarrhizus. The method allowed the correct identification of all targeted pathogens using extracted DNA or by colony PCR, showed no cross-reactivity with nontargeted species and allowed identification of different species in mixed infections. Sensitivity reached 10 to 1 pg of DNA and was suitable for clinical samples from sterile sites, with a sensitivity of 89% and specificity of 100%. Overall, the study showed that the new method is suitable for the identification of the ten most important fungal species involved in IFI, not only from positive blood cultures but also from clinical samples from sterile sites. The method provides a unique characteristic, of seeing the peak in the specific region of the panel with the correct fluorescence dye, that aids the ruling out of unspecific amplifications. Furthermore, the panels can be further customized, selecting markers for different species and/or resistance genes.

Antimicrobial Properties of Composites of Chitosan-Silver Doped Zeolites.

The antimicrobial functionality of composites constituted by chitosan with silver-doped zeolites was developed and characterized. A composite with chitosan particles and silver-doped zeolites was synthesized using an ionic gelation process with sodium tripolyphosphate. The chitosan silver-doped zeolites composite obtained presented sizes up to 5 µm, while the silver-doped zeolites had an average size between 0.5 µm and 3.3 µm. The synthesized chitosan silver-doped zeolites composites, as well as the silver-doped zeolites and the chitosan dissolution, were characterized through X-ray diffraction, Fourier Transform Infrared spectroscopy and scanning electron microscopy. The electro kinetic behaviour of chitosan, silver-doped zeolites and chitosan silver-doped zeolites composite was evaluated under different pH conditions. The antimicrobial activity of the composites was evaluated in terms of minimum inhibitory concentrations and minimum lethal concentrations and the results suggest that the chitosan silver-doped zeolites composites show antimicrobial activity against gram-negative and gram-positive bacteria, Escherichia coli and Staphylococcus aureus, respectively and against Candida albicans. The results here presented support the potential application of the composite of chitosan with silver-doped zeolites in the functionalization of textiles with antimicrobial properties.

Effect of Natural Preservatives on the Nutritional Profile, Chemical Composition, Bioactivity and Stability of a Nutraceutical Preparation of Aloe arborescens.

Citric acid, quercetin, dried chestnut flowers and an aqueous extract of chestnut flowers were screened as candidates for preserving a drinkable nutraceutical preparation for 45 days. The assays encompassed antioxidant and antimicrobial activities, nutritional and chemical profiles, and individual profiles of fatty acids and mineral composition, all of which in comparison with a sodium benzoate, a synthetic preservative. The centesimal composition of the nutraceutical formulation was mainly composed of carbohydrates, followed by proteins and fat, with moisture levels between 66% and 71%. Palmitic and stearic acid were the most abundant fatty acids, while calcium and magnesium where the minerals in higher amount. Anthroquinones, followed by flavonoids where the most abundant groups of phenolic compounds. In terms of the preserving effects of the extracts, the chestnut flowers and the citric acid were the most effective natural preservatives, which better preserved phenolic compounds. Furthermore, these two ingredients also revealed the strongest capacity to control the microbial growth in the formulation by inhibiting the growth of food contaminants. In general, these ingredients revealed higher preservation capacity than sodium benzoate, while not altering the nutritional and fatty acid profile. The chestnut flowers and citric acid could be used to preserve foods, food supplements, and nutraceutical formulations after passing the required regulatory procedures for food additives.

Dó, Ré, Mi nas emoções e sentimentos: a música como mediador expressivo na intervenção de enfermagem / C, D, E in emotions and feelings: music as an expressive mediator in nursing intervention

O presente relatório enquadra-se no âmbito do Curso de Mestrado em Enfermagem na área de Especialização em Enfermagem de Saúde Mental e Psiquiatria, em contexto do estágio num serviço de internamento de pedopsiquiatria e posteriormente em contexto de hospital de dia de pedopsiquiatria. A temática do relatório incidiu sobre a música como mediador expressivo das emoções e sentimentos em adolescentes em que tivemos como objetivos compreender a importância da música como mediador expressivo na gestão das emoções e sentimentos. A música é uma constante na vida dos adolescentes quer para estudar, quer para ouvir juntamente com um grupo de amigos, ou até mesmo no caminho para a escola. Mas qual a importância que lhe dão? E de que forma pode ajudar na expressão de sentimentos e emoções, muitas vezes condicionada nesta fase do desenvolvimento? Foram desenvolvidas intervenções de enfermagem no âmbito psicoterapêutico em grupo utilizando como mediador expressivo o movimento, a música e o desenho. Com este trabalho é possível a compreensão da utilização do mediador a música na relação terapêutica em enfermagem de forma a trabalhar de forma clara sentimentos e emoções. Assim, conseguimos através das atividades desenvolvidas que os adolescentes acedessem, tomassem consciência e verbalizassem alguns sentimentos e emoções como a felicidade, a tranquilidade, a surpresa, conforto, o amor, bem como algumas emoções difíceis como a zanga, a tristeza e a raiva. Podemos concluir que a música é um mediador de privilegiado acesso aos sentimentos e emoções, e que os adolescentes conseguem através da vivência da música identificar, nomear os sentimentos associados, e ainda expressá-los de forma adequada, beneficiando assim da sua utilização como recurso para melhorar a saúde mental.

This report is driven by the field work performed in the context of the Nursing Master's Degree in the area of specialization in Mental Health Nursing and Psychiatry, while attending a psychiatric internship in pediatric patient service and later on in specialized treatment team in community The theme of the report is about music as an expressive mediator of emotions and feelings in adolescents ,in which we aimed to understand the importance of music as an expressive mediator in the management of emotions and feelings. Music is a constant in the lives of teenagers either to study, to listen together with a group of friends, or even on the way to school. But what importance do they give to the music? And how can it help in the expression of feelings and emotions, in this particular stage of development? Nursing interventions were developed in the psychotherapeutic group using movement, music and drawing as an expressive mediator. With this work it is possible to understand how this mediator is important and helpful to work clearly on feelings and emotions. Through the activities developed, adolescents were able to access, become aware and verbalize some feelings and emotions such as happiness, tranquility, surprise, comfort, and love, as well as some difficult emotions such as anger, sadness and anger. We can conclude that music is a privileged mediator to accessed feelings and emotions on adolescents , and then they can named and associated feelings, and still express the appropriate form, thus benefiting from its use as a resource to improve health mental.

Routes for Specialization in Psychology throughout Europe.

The specialization of psychology helps to delineate fields in the practice of psychology. When establishing professional qualification criteria, associations seek to promote, in their members, scientific skills and knowledge considered fundamental for the practice of psychology in a given area. The present study reports on a survey of the member associations of the European Federation of Psychologists Associations (EFPA). The survey inquired about: (a) the initial requisites for entering the profession and (b) additional requisites for specialization. Of the 37 associations contacted, 14 replied and we retrieved the information of 12 associations from their official websites. The results indicate that specialization is widespread throughout Europe and is independent of the regulation of the profession. In almost half of the countries considered, the specialization process is completed in universities-it is frequently associated with the postgraduate level of the EuroPsy-and relies on conventional learning methods. The number of existing specialties in psychology is very high, but the traditional areas (clinical and health, education, and social/organizational) are more prevalent. The results are discussed in light of the advantages, but also the challenges posed by the specialization in psychology. A continuous model of the specialization of psychology is proposed with two stages: broad and advanced psychology areas.

Wound Navigator Profiling: scoping review. / Competências do Gestor de Feridas: scoping review.

OBJECTIVE: Map specific skills of the Wound Navigator. METHODS: A scoping review of complete and free articles in the databases CINAHL®, Nursing & Allied Health Collection, Cochrane Plus Collection, MedicLatina, MEDLINE® and 12 specialist associations in tissue viability, references in Portuguese, English, Spanish and French, with no time limit. Realized by two researchers in August 2017, of the 746 articles found, 19 met the inclusion and exclusion criteria. RESULTS: Four competency domains were identified: care (prevention/treatment of wounds and advanced therapies, decision-making; empowerment and clinical supervision), quality (specialized training; peer qualification; research and audit), and leadership (change agent; teamwork and consultant) and management (material selection/cost control). CONCLUSIONS: With four areas of competences, the Wound Navigator in partnership focuses on redefining people's life plans in the presence of wounds.