Clinical and pathological features associated with high-risk, multiple, and recurrent basal cell carcinomas: a retrospective cohort analysis from the Levantine coast of the Mediterranean Sea.

Basal cell carcinoma (BCC) data coming from the Levantine coast of the Mediterranean Sea are limited. The study aimed to primarily analyze the demographic, clinical, pathological, and prognostic characteristics of BCC in this region of the world and secondarily identify features associated with high-risk, recurrent, or multiple BCCs. Patients with at least one diagnosis of BCC registered in the pathology department between January 2015 and December 2019 were included in this analytical retrospective single-center cohort study. Patients with basal cell nevus syndrome were excluded. Patients' characteristics and pathological features were collected through file check for a first analysis. Risk factors and evolution were sought through a phone call interview for the second analysis. The first analysis included 506 BCCs corresponding to 365 patients with a mean age of 65 ± 15 years, twenty-two (6%) were less than 40 years old, 180 (49.3%) were women, and 85 (23.3%) had two or more BCCs. The second analysis included 279 BCCs corresponding to 205 patients. Periorificial and infiltrative BCCs were more frequent in men. Periorificial tumors were more frequently nodular or infiltrative and were associated with recurrence. Tumors with perineural involvement were histologically never nodular nor superficial. Recurrence was more frequent in BCCs having periorificial location, a size larger than 2 cm, or an infiltrative subtype. Multiple BCCs were more frequent in patients with light skin type or familial history of skin cancer. High-risk BCCs were more common in patients with low sun exposure.

[Prospective study about predictive factors of bed sore occurrence in a university hospital center]. / Etude prospective sur les facteurs prédictifs de survenue d'escarres dans un centre hospitalier.

INTRODUCTION: The aims of the study are to search the correlation between risk factors and occurrence of bed sores in a university hospital center. PATIENTS AND METHODS: Transversal retrospective study on hospital files of patients presenting bed sores. Data collection and statistics are done using Microsoft Excel 2003 and SPSS v13.0 softwares. RESULTS: 249 declarations of bed sores. Descriptive analysis. Age: 68 +/- 17 years. Male predominance: 57.5%. High risk patients : 60%. Number of risk factors 2 +/- 1 including in decreasing frequency : circulatory troubles, bed rest, diabetes, neurologic deficiency, nutritional deficiency, dementia, incontinency. Average number of bed sores: 2 +/-1. One or 2 locations: 76%. Univariable analysis--The correlation between the risk factors (bed sore risk score, incontinency, circulatory troubles and dementia) and the bed sore characteristics is significatively important with p < 0.05. CONCLUSION: The study shows the predictive risk factors of bed sore. These factors must be taken into consideration in the evaluation of patients.