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2.
Sci Rep ; 10(1): 16229, 2020 10 01.
Article En | MEDLINE | ID: mdl-33004827

The purpose was to predict the crown-to-implant ratio variation in the edentulous posterior mandibles rehabilitated with short dental implants. Hence, vertical and horizontal dimensions of dentulous posterior mandibles in a sample of 18- to 25-year-olds were measured, and correlations of these dimensions with sex and site were investigated. Mandibular computed tomography scans from 100 subjects were considered. Vertical and horizontal bone and tooth measurements were taken at the sites of the second premolar (PM), and the mesial and distal roots of the first and second molars (M1m, M1d, M2m and M2d, respectively). A hypothetical crown-to-implant ratio (C/I R) was calculated assuming the insertion of short and extra short implants (5, 6 or 7 mm), at 1.5 mm from the inferior alveolar canal, maintaining the position of the existing occlusal plane. All vertical bone dimensions decreased from the PM to the M2d. Width measurements increased from the mesial (PM) to the distal sites (M1m, M1d, M2m and M2d). Males had significantly greater vertical and horizontal measurements than females at all sites. The mean C/I R was higher than 2 for all sizes of implant. The C/I R was lower for the second molar than for the second premolar, while it was similar for the first molar and the second premolar. Males had a higher C/I R than females. Computed tomography can be used to study the anatomical features of alveolar bone, and to predict some clinical aspects of prosthetic rehabilitation with implants, such as the crown-to-implant ratio in conditions of serious bone atrophy.


Alveolar Process/diagnostic imaging , Dental Implants , Mandible/diagnostic imaging , Tooth Crown/diagnostic imaging , Adolescent , Adult , Alveolar Process/anatomy & histology , Humans , Jaw, Edentulous/diagnostic imaging , Jaw, Edentulous/pathology , Male , Mandible/anatomy & histology , Radiography, Dental , Retrospective Studies , Tomography, X-Ray Computed , Tooth Crown/anatomy & histology , Young Adult
3.
Implant Dent ; 26(1): 66-72, 2017 Feb.
Article En | MEDLINE | ID: mdl-27824716

AIMS: To evaluate the ridge dimensions of posterior sextant in totally edentulous mandibles. MATERIAL AND METHODS: Cone beam computed tomography scans of 136 patients were retrospectively included for analysis. At sites corresponding to the second premolar (site a) and the mesial and distal root of first molar (sites b and c, respectively), bone height (BH) and bone width (BW) were measured. RESULTS: BH significantly decreased from site a (11.20 ± 4.03 mm) to site c (10.28 ± 3.33 mm). Males showed a significantly higher BH compared with females at all sites (P < 0.001), No significant impact of age on BH was found. BW increased from coronal to apical at all sites. At all height levels, BW increased from mesial to distal (BWc > BWb > BWa). CONCLUSIONS: BH decreased from mesial to distal, whereas BW showed an increase. Sex showed a significant impact on BH, with males having on average a 2.8 mm greater height than females, but not on BW. Age did not significantly influence the dimensions of the residual bone crest.


Alveolar Process/diagnostic imaging , Cone-Beam Computed Tomography , Jaw, Edentulous/diagnostic imaging , Adult , Aged , Aged, 80 and over , Alveolar Process/pathology , Cone-Beam Computed Tomography/methods , Female , Humans , Jaw, Edentulous/pathology , Male , Middle Aged , Radiography, Dental , Retrospective Studies
4.
Int J Mol Sci ; 15(2): 3088-117, 2014 Feb 20.
Article En | MEDLINE | ID: mdl-24562333

Injury to peripheral nerves can occur as a result of various surgical procedures, including oral and maxillofacial surgery. In the case of nerve transaction, the gold standard treatment is the end-to-end reconnection of the two nerve stumps. When it cannot be performed, the actual strategies consist of the positioning of a nerve graft between the two stumps. Guided nerve regeneration using nano-structured scaffolds is a promising strategy to promote axon regeneration. Biodegradable electrospun conduits composed of aligned nanofibers is a new class of devices used to improve neurite extension and axon outgrowth. Self assembled peptide nanofibrous scaffolds (SAPNSs) demonstrated promising results in animal models for central nervous system injuries, and, more recently, for peripheral nerve injury. Aims of this work are (1) to review electrospun and self-assembled nanofibrous scaffolds use in vitro and in vivo for peripheral nerve regeneration; and (2) its application in peripheral nerve injuries treatment. The review focused on nanofibrous scaffolds with a diameter of less than approximately 250 nm. The conjugation in a nano scale of a natural bioactive factor with a resorbable synthetic or natural material may represent the best compromise providing both biological and mechanical cues for guided nerve regeneration. Injured peripheral nerves, such as trigeminal and facial, may benefit from these treatments.


Nanostructures/chemistry , Peripheral Nerve Injuries/pathology , Animals , Biocompatible Materials/chemistry , Biocompatible Materials/therapeutic use , Humans , Nanofibers/chemistry , Nanostructures/therapeutic use , Nerve Regeneration , Peripheral Nerve Injuries/therapy , Polymers/chemistry , Tissue Engineering , Tissue Scaffolds
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