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Arch Physiol Biochem ; 125(1): 85-91, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-29431478

RESUMEN

This study investigate the effects of high-intensity interval training (HIIT) on systemic levels of inflammatory and hormonal markers in postmenopausal women with metabolic syndrome (MS). Fifteen postmenopausal women with MS completed the training on treadmills. Functional, body composition parameters, maximal oxygen uptake (VO2max), and lipid profile were assessed before and after HIIT. Serum or plasma levels of cytokines and hormonal markers were measured along the intervention. The analysis of messenger RNA (mRNA) expression of these cytokines was performed in peripheral blood mononuclear cells (PBMC). VO2max and some anthropometric parameters were improved after HIIT, while decreased levels of proinflammatory markers and increased levels of interleukin-10 (IL-10) were also found. Adipokines were also modulated after 12 weeks or training. The mRNA expression of the studied genes was unchanged after HIIT. In conclusion, HIIT benefits inflammatory and hormonal axis on serum or plasma samples, without changes on PBMC of postmenopausal MS patients.


Asunto(s)
Adipoquinas/metabolismo , Entrenamiento de Intervalos de Alta Intensidad , Síndrome Metabólico/metabolismo , Posmenopausia , Adipoquinas/sangre , Biomarcadores/metabolismo , Composición Corporal , Femenino , Regulación de la Expresión Génica , Hormonas/metabolismo , Humanos , Leucocitos Mononucleares/metabolismo , Síndrome Metabólico/sangre , Síndrome Metabólico/fisiopatología , Persona de Mediana Edad
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