Condition of hemodynamics in the pulmonary circulation of patients with chronic obstructive pulmonary disease (copd) concurrent with metabolic syndrome with hypertrophy and atrophy of the myocardium

Introduction: In recent years, COPD is observed as not an isolated, but an associated pathology, in particular, concurrent with metabolic syndrome. The aim of the research is to identify the differences in changes of the rheopulmonography parameters (RPG) depending on the presence of hypertrophy or atrophy of the right ventricular myocardium in patients with COPD concurrent with metabolic syndrome. Material and Methods: We studied changes in rheopulmonography (RPG) in 145 patients with chronic obstructive pulmonary disease (COPD) concurrent with metabolic syndrome. Results: We detected precapillary hypertension of the pulmonary circulation in patients with right ventricular myocardial hypertrophy: anacrotism serration; flattened peak of the systolic wave; decreased Vcp; high placement of incisura; horizontal course of catacrotism; decreased amplitude of the systolic wave (in this case, due to a greater increase in the resistance of the blood flow in the pulmonary vessels than the decreased impact volume of the right ventricle); prolonged Q-a (in this group of patients, it depends more on hypertension of the pulmonary circulation than on the reduction of contractile function of the myocardium). In atrophy of the right ventricular myocardium, the following changes in the RPG were revealed: decreased systolic wave at its dramatic rise; prolonged Q-a (in this case, due to the weakened heart contraction); Vmax reduction (it reflects the reduction of myocardial contractility); in hypertrophy of the myocardium, Vcp., unlike RPG, does not decrease, which is explained by the decrease in the pressure of the pulmonary circulation. Conclusions: We believe that these changes in RPG allow differentiating hypertrophy and right ventricular myocardial atrophy along with established diagnostic criteria, and can be used as markers for the diagnosis and treatment of COPD concurrent with metabolic syndrome.

Аnalysis of knowledge of students of higher educational institutions of poltava about the harmfulness of drug use.

OBJECTIVE: Introduction: The urgency of the topic is due to the fact that in recent years in Ukraine a part of youth who use narcotic drugs and psychoactive substances is growing. Today there are more than a quarter of billion drug addicts in the world. This number includes those who have tried drugs at least once. Among them - about 27 million drug addicts that are in need of treatment. The aim: to analyze the knowledge of the students of higher educational institutions of Poltava about various issues related to drug addiction. PATIENTS AND METHODS: Materials and method: 600 questionnaires of students who study at the universities (Poltava). The following methods were used: historical - analytical and bibliosemantic, medico-statistical, sociological, system approach and system analysis. RESULTS: Results: Student youth responded to various questions that were presented in the questionnaire, about various issues related to drug addiction. 26 % of respondents indicated that they know places where drugs can be purchased. To the question «Do you know what drugs are?¼ оnly 7 % answered «No¼. 2, 5 % of those surveyed met with drug users on the street. 13 ± 1, 51 % (р<0, 05) of the respondents admitted that they were irritated when they were criticized for using narcotic drugs and only 9 ± 1, 25 % (р<0, 05) felt guilty about abuse. CONCLUSION: Сonclusions: Students should be aware of the problem of the use of psychoactive substances, be aware of the legislative framework for the prevention of consumption, turnover and any manipulations with psychoactive substances.