[The complex decompressive dialysis surgery of destructive forms of pancreatitis].

The way of comprehensive treatment of acute destructive pancreatitis is worked out. The method is based on multicomponent sanitation of pancreatic region: decompression of the pancreas parenchyma is followed by the isolated dialysis of the upper pole of the gland.

[Anatomic-topographical characteristics of the pancreas as the guidelines for the surgical interventions in destructive forms of pancreatitis].

Using polymer techniques (plastination), research was conducted on the corpses of 62 human subjects, both male and female, who died at the age of 40-60 and had no signs of pathology of the abdominal organs and of retroperitoneal space, and on 7 corpses of the subjects who died as a result of a total pancreonecrosis. In total slices 1 mm thick, cut in frontal, sagittal and horizontal planes, the profile areas of the pancreas and connective tissue structures, surrounding the organ, were measured, and their correlation was determined. It was demonstrated that the existence of a strongly pronounced cellular tissue space, totally surrounding the pancreas with the minimal thickness of 5 mm, creates topographic-anatomically substantiated possibilities for the development of rational operation accesses and regional sanative methods. An anatomically substantiated method of closed dialysis of a cellular tissue space of the pancreatic region in destructive forms of pancreatitis, was developed, including conducting the drainage tubes to the pancreas area from both sides through the space between retrotransversal and anterenal fascia, as well as drainages through the space between parietal peritoneum and retroperitoneal fascia on 2 levels by three drainage tubes. The method is tested on 32 patients. It is shown that the flowing drainage of the retroperitoneal space according to the close type in patients with pancreonecrosis, prevents the generalization of the process, accelerates the process of detoxication by 2.4 times and decreases the mortality rate of pancreonecrosis to 10%.

[Effect of enterosorption on the liver morphology anf function in mechanical jaundice]. / Vliianie énterosorbtsii na morfofunktsional'noe sostoianie pecheni pri mekhanicheskoi zheltukhe.

Using histological, morphometric and biochemical methods, the comparative analysis of the effect of carbon-mineral enterosorbent SUMS-1 and of new generation aluminium oxide-based enterosorbent SIAL on the course of pathologic process--experimentally induced mechanical jaundice--was performed. The possibility of their use for the correction of morpho-functional disturbances of liver tissues is demonstrated. The conduction of clinical trials for the clinical application of these substances is recommended.

[Structural changes in the liver of dogs under physical training at high altitude]. / Strukturnye izmeneniia v pecheni u sobak pri fizicheskikh trenirovkakh v usloviiakh vysokogor'ia.

Physical training in mountains leads to significant structural disorders in dog liver. In early stages (up to 15 days of staying in mountains) dystrophic processes prevail in trained animals liver, while in later ones (on day 30), repair processes take over, although destruction traits are still retained.

[Blood vessels and tissue structures of the pituitary in the presence of ischemia]. / Krovenosnye sosudy i tkanevye struktury gipofiza pri ego ishemii.

Modelling of the brain ischemic hypoxia, the hypophysis including, by ligation of the left internal carotid artery in dogs results in weight enlargement of the hypophysis, marked edema of the parenchyma, discomplexity of the cellular elements of the anterior pituitary lobe with morphological signs of hypofunctional condition of the increting cells in the organ studied. Ischemic hypoxia produces lumen augmentation of blood vessels in some areas of the anterior pituitary lobe with resulting increased circulatory capacity in the anterior pituitary lobe. Comparing with the data available in the literature, we conclude that blood circulation manifests a nonspecific reaction to different hypoxic models, while cellular reaction is more specific.