Visual Acuity , Humans , Female , Male , Cornea/abnormalities , Cornea/pathology , Cornea/diagnostic imaging , Corneal Wavefront Aberration/physiopathology , Corneal Wavefront Aberration/diagnosis , Infant , Glaucoma/congenital , Glaucoma/physiopathology , Glaucoma/diagnosis , Intraocular Pressure/physiology , Hydrophthalmos/diagnosis , Hydrophthalmos/physiopathology , Hydrophthalmos/surgery , Child, Preschool
OBJECTIVE: To compare corneal densitometry and topography variables in patients with primary congenital glaucoma (PCG) and healthy subjects. MATERIAL AND METHODS: Cross sectional study, consecutive recruitment with gender- and age-matched control group. Forty eyes of 40 patients in each group were studied with Pentacam corneal topography. The variables compared between the two groups were: intraocular pressure (IOP), visual acuity (VA) and Pentacam (Oculus, Wetzlar, Germany) corneal topography measurements: mean and maximum keratometry (Km, Kmax), cylinder (Cyl), anterior elevation apex (AEA), central anterior elevation (CAE), maximum anterior elevation (MAE), posterior elevation apex (PEA), central posterior elevation (CPE), maximum posterior elevation (MPE), pachymetry and anterior, mid-stromal and posterior corneal densitometry in the 0-2mm, 2-6mm, 6-10mm zones. RESULTS: Significant differences between patients and healthy controls were detected in the topographic variables MAE (P=0.002) and MPE (P<0.001), and in all the densitometry variables (anterior, mid-stromal, posterior for the 0-2mm, 2-6mm and 6-10mm zones) (P<0.001 each). In the PCG group, negative correlation was observed between VA and total densitometry (r=-0.49; P=0.004). CONCLUSION: Patients with PCG and healthy subjects display differences in corneal densitometry and topographic measurements. PCG patients show greater corneal density with an inverse relationship between visual acuity and higher elevation (anterior and posterior values).
Cornea/diagnostic imaging , Glaucoma/congenital , Glaucoma/diagnosis , Adolescent , Adult , Case-Control Studies , Child , Child, Preschool , Cornea/pathology , Corneal Topography , Cross-Sectional Studies , Densitometry , Female , Glaucoma/pathology , Humans , Infant , Infant, Newborn , Male , Organ Size , Prognosis , Young Adult
INTRODUCCIÓN: El término 'poppers' se refiere a productos a base de nitritos de alquilo utilizados con fines recreativos. CASO CLÍNICO: Varón de 40 años de edad, consumidor habitual de 'popper' que refiere visión borrosa en ambos ojos y fotofobia. La agudeza visual fue 0,63/1 en ambos ojos. Se apreció una lesión macular amarillenta de aspecto viteliforme bilateral en la funduscopia y una interrupción de la línea IS/OS en la tomografía de coherencia óptica. DISCUSIÓN: Este es el primer caso de 'maculopatía por poppers' registrada en España. Los hallazgos y síntomas clínicos son similares a los casos anteriores reportados
INTRODUCTION: The term 'poppers' refers to products made of volatile alkyl nitrites used for recreational practices. Clinical case: 40 year old man reported blurred vision in both eyes and photophobia, and admitted regular use of 'poppers'. Best corrected visual acuity was 0.63/1 in both eyes. Bilateral yellowish vitelliform macular lesions were present in both eyes in the funduscopy, as well as a disruption of the IS/OS line in the optical coherence tomography. DISCUSSION: This is the first case of 'poppers maculopathy' registered in Spain. Clinical findings and symptoms are similar to previous reported cases
Humans , Male , Adult , Retinal Diseases/chemically induced , Alkylmercury Compounds/adverse effects , Vision Disorders/etiology , Risk Factors , Illicit Drugs/adverse effects , Substance-Related Disorders/complications
INTRODUCTION: The term «poppers¼ refers to products made of volatile alkyl nitrites used for recreational practices. CLINICAL CASE: 40 year old man reported blurred vision in both eyes and photophobia, and admitted regular use of «poppers¼. Best corrected visual acuity was 0.63/1 in both eyes. Bilateral yellowish vitelliform macular lesions were present in both eyes in the funduscopy, as well as a disruption of the IS/OS line in the optical coherence tomography. DISCUSSION: This is the first case of «poppers maculopathy¼ registered in Spain. Clinical findings and symptoms are similar to previous reported cases.
Illicit Drugs/adverse effects , Macular Degeneration/chemically induced , Nitrites/adverse effects , Photophobia/chemically induced , Adult , HIV Infections/complications , Humans , Infant , Macular Degeneration/diagnostic imaging , Male , Ophthalmoscopy , Spain , Substance-Related Disorders/complications , Tomography, Optical Coherence
Hypertension, Pulmonary/complications , Pseudotumor Cerebri/complications , Causality , Cerebrospinal Fluid Pressure/physiology , Digoxin/therapeutic use , Diuretics/therapeutic use , Emergencies , Female , Humans , Hypertension, Pulmonary/drug therapy , Hypertension, Pulmonary/physiopathology , Middle Aged , Papilledema/etiology , Pseudotumor Cerebri/etiology , Pseudotumor Cerebri/physiopathology , Vision Disorders/etiology
