Abscess/etiology , Catheterization, Peripheral/adverse effects , Fat Necrosis/diagnosis , Panniculitis/diagnosis , Subcutaneous Fat/pathology , Biopsy , Diagnosis, Differential , Fat Necrosis/etiology , Fat Necrosis/pathology , Female , Humans , Infant, Newborn , Infant, Newborn, Diseases , Panniculitis/etiology , Panniculitis/pathology , Skin/pathology
Acne Vulgaris/drug therapy , Acne Vulgaris/economics , Cost Savings/economics , Cost of Illness , Financing, Personal/economics , Isotretinoin/therapeutic use , Patient Acceptance of Health Care , Remote Consultation/economics , Risk Management/economics , Absenteeism , Adolescent , Adult , Female , Follow-Up Studies , Humans , Insurance Coverage/economics , Male , Middle Aged , Office Visits/economics , Patient Satisfaction , Pennsylvania , Surveys and Questionnaires , Young Adult
Phytophotodermatitis is a phototoxic cutaneous eruption due to skin exposure to furocourmarins combined with ultraviolet light. Bizzare linear patterns, ranging from erythema to bullae with residual hyperpigmentaion, is the clinical clue to this diagnosis. Avoidance of furocoumarins in direct sunlight can prevent recurrences.
Citrus/adverse effects , Dermatitis, Phototoxic/diagnosis , Dermatitis, Phototoxic/etiology , Furocoumarins/adverse effects , Sunlight/adverse effects , Adolescent , Female , Humans
We investigated the incidence of phototoxic skin reactions in pediatric BMT recipients treated with voriconazole. Nine out of 40 patients (22.5%), all Caucasian, developed skin lesions in sun-exposed distributions. Dermatologic findings included sunburn-like erythema, pseudo-porphyria, linear papulovesicular lesions, severe erosive cheilitis, dermatoheliosis and lentigines. Patients were treated with sun avoidance, high-potency sunscreens, and topical steroids with significant improvement in all cases. Prolonged voriconazole use requires close monitoring for chronic skin toxicities. Long-term risks including the risk of skin cancer need to be investigated.
Antifungal Agents/adverse effects , Bone Marrow Transplantation , Photosensitivity Disorders/chemically induced , Pyrimidines/adverse effects , Sunlight/adverse effects , Triazoles/adverse effects , Allografts , Antifungal Agents/administration & dosage , Child , Female , Humans , Male , Photosensitivity Disorders/pathology , Photosensitivity Disorders/prevention & control , Pyrimidines/administration & dosage , Retrospective Studies , Skin Neoplasms/prevention & control , Sunscreening Agents/administration & dosage , Triazoles/administration & dosage , Voriconazole
We present the case of a 20-month-old boy with congenital neutropenia for which he was being treated with granulocyte colony-stimulating factor (G-CSF) who developed bullous Sweet's syndrome. Because of the challenging and extensive differential diagnosis of an acute bullous eruption in an immunocompromised child, we highlight the importance of a prompt and precise diagnosis before initiation of any systemic therapy in children with Sweet's syndrome.
Blister/chemically induced , Granulocyte Colony-Stimulating Factor/adverse effects , Neutropenia/congenital , Sweet Syndrome/chemically induced , Biopsy , Blister/drug therapy , Glucocorticoids/therapeutic use , Humans , Infant , Male , Neutropenia/drug therapy , Sweet Syndrome/drug therapy
Cytomegalovirus (CMV) can rarely present with skin findings. Cutaneous CMV is most often found in patients who are immunocompromised because of acquired immunodeficiency syndrome, lymphoma, or other conditions. We present a rare case of an immunocompetent 7-week-old girl with a perianal ulcer attributed to CMV.
Antiviral Agents/therapeutic use , Cytomegalovirus Infections/diagnosis , Cytomegalovirus Infections/drug therapy , Ganciclovir/analogs & derivatives , Skin Ulcer/virology , Biopsy , Buttocks , Diagnosis, Differential , Female , Ganciclovir/therapeutic use , Humans , Infant , Nepal , Valganciclovir
Fever/drug therapy , Lymphadenitis/drug therapy , Pharyngitis/drug therapy , Stomatitis, Aphthous/drug therapy , Adrenal Cortex Hormones/therapeutic use , Anti-Infective Agents/therapeutic use , Child , Dapsone/therapeutic use , Female , Fever/complications , Humans , Lymphadenitis/complications , Pharyngitis/complications , Stomatitis, Aphthous/complications
Invasive fungal infections in children have increased in recent years, coinciding with greater survival of preterm neonates and children with immunodeficiencies, more intense chemotherapy regimens, and greater use of stem cell and solid organ transplantation. We describe a case of an immunosuppressed neonate who developed cutaneous Exserohilum rostratum infection.
Ascomycota/immunology , Dermatomycoses/immunology , Facial Dermatoses/immunology , Immunocompromised Host , Lymphohistiocytosis, Hemophagocytic/immunology , Opportunistic Infections/immunology , Ascomycota/isolation & purification , Dermatomycoses/microbiology , Facial Dermatoses/complications , Humans , Infant, Newborn , Lymphohistiocytosis, Hemophagocytic/complications , Male , Opportunistic Infections/microbiology
