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Clin Transl Oncol ; 17(12): 1036-42, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-26650487

RESUMEN

Cervical cancer (CC) is the second most common cancer worldwide, strongly linked to high-risk human papilloma virus infection. Although screening programs have led to a relevant reduction in the incidence and mortality due to CC in developed countries, it is still an important cause of mortality in undeveloped countries. Clinical stage is still the most relevant prognostic factor. In early stages, the primary treatment is surgery or radiotherapy, whereas concomitant chemo-radiotherapy is the conventional approach in locally advanced stages. In the setting of recurrent or metastatic CC, for the first time ever, the combination of chemotherapy plus bevacizumab prolongs the overall survival beyond 12 months. Therefore, this regimen is considered by most of the oncologist a new standard of care for metastatic/recurrent CC.


Asunto(s)
Guías de Práctica Clínica como Asunto/normas , Neoplasias del Cuello Uterino/diagnóstico , Neoplasias del Cuello Uterino/terapia , Ensayos Clínicos como Asunto , Terapia Combinada , Manejo de la Enfermedad , Detección Precoz del Cáncer , Femenino , Humanos , Oncología Médica , Estadificación de Neoplasias , Pronóstico , Sociedades Médicas
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