[Antibodies to E. coli and circulating immune complexes in the bile and blood serum of patients with suppurative cholangitis]. / Antitela k E. coli i tsirkuliruiushchie immunnye kompleksy v zhelche i syvorotke krovi bol'nykh gnoinym kholangitom.

It has been found out for the first time that in 55% of cases presenting with purulent cholangitis, there are antibodies to a clinical strain of E. coli in the bile taken intraoperatively from major bile duct whereas museum specimens of E. coli strain are free from the above antibodies. Immune complexes were identified in the bile of all examined patients (0.316 +/- 0.085 arbitrary units). In the blood serum of patients with purulent cholangitis, antibodies to the clinical strain E. coli are not detectable, while there are great counts of circulating immune complexes (0.928 +/- 0.242 arbitrary units). Based on the findings obtained a conclusion was reached about relative independence of local immunity of the biliary tract.

[Relation of atherogenesis and T-immunodeficiency]. / Vzaimosvia'z aterogeneza i T-immunodefitsita.

Experiments on rabbits have shown that state of T-immunodeficiency induced by persisting virus infection promotes atherogenesis. Correction of age immunodeficiency by transplantation of the autologous bone marrow taken in young age considerably retards the atherosclerosis development. Inhibition of atherogenesis is also achieved by introduction (to animals) of natural thymic vilosene preparation which compensates a decrease in the functional activity of the thymus gland occurring under conditions of experimental hyperlipidemia.

[Thymus participation in realizing the immunomodulating action of hydrocortisone]. / Uchastie vilochkovoi zhelezy v realizatsii immunomoduliruiushchego deistviia gidrokortizona.

It has been shown in experiments on CBA mice that in certain conditions injection of hydrocortisone (10 mg/kg) results in suppression of the delayed type hypersensitivity reaction and prolongation of the skin allograft survival. Preliminary thymectomy abolishes the immunomodulating effect of the drug, being, in the authors' opinion, the evidence for thymus involvement in mediation of the immuno-suppressive effect of hydrocortisone.