[Importance of dietary sodium in the hypercalciuria syndrome and nephrolithiasis]. / Wplyw podazy sodu w diecie na wydalanie wapnia w kamicy nerkowej z idiopatyczna hiperkalciuria.

The studies involved 20 children with idiopathic hypercalciuria (IH). An influence of urinary sodium excretion, and reflection of its intake, on urinary calcium excretion has been assessed. Children who were normocalciuric had significancy lower values of urine sodium excretion when compared with those with persisting hypercalciuria. The main factor responsible for hypercalciuria in children seemed to be urine sodium excretion. As urine sodium excretion reflects its intake, reduction dietary salt, rather than calcium intake, may be useful in the management of children with hypercalciuria and nephrolithiasis.

[Evaluation of treatment and preventive care for recurrent urolithiasis in children]. / Ocena skutecznosci leczenia i profilaktyki kamicy nawrotowej ukladu moczowego u dzieci.

Among 425 children with urolithiasis treated in the Paediatric Clinical Department of the National Research Institute of Mother and Child in Warsaw between 1976-1997, 50 of them i.e. 11.7% (26 boys and 24 girls) had recurrent urolithiasis. Patients' age was from 10 months to 16 years and 5 months. The number of recurrences of uroliothiasis before treatment in the Institute was from 1 to 8. Most of the children had numerous surgical operations, some of them excreted stones spontaneously. The etiology was determined in all cases. A metabolic cause of urolithiasis was found in 34 cases, i.e. 68% of the analysed group. They were as follows: idiopathic hypercalcuria--24 cases, uric acid urolithiasis--5 cases, cystynuria--4 cases, and incomplete distal renal tubular acidosis--1 case. Other reasons for urolithiasis were: infection--7 cases, idiopathic urolithiasis--8 cases, ren spongiosum--1 case. Prevention of recurrences depending on the etiology was successful. In 45 cases no recurrences were found. Recurrent urolithiasis was observed in 4 cases of cystynuria and in one case of incomplete tubular acidosis. The observation period was from 3-19 years.

[Etiologic factors for purulent meningitis in children. Twenty years of personal observations]. / Czynniki etiologiczne ropnego zapalenia opon mózgowo-rdzeniowych u dzieci. Dwadziescia lat obserwacji wlasnych.

Etiological agents in purulent meningitis cases hospitalized during two 9 years periods: 1977-1985 and 1988-1996 were compared. While the percentage of cases caused by Neisseria meningitidis was similar in the two analyzed periods (55.7% i 66.5%, respectively), the percentage of cases caused by Streptococcus pneumoniae decreased from 33.5% to 8.4% and the percentages of cases caused by Haemophilus influenzae type b increased from 0.6% to 14.2%. The analysis of the sensitivity of isolated strains of H. influenzae type b shows the occurrence of strains resistant to ampicillin and chloramphenicol.

[Clinical evaluation of Uro-Vaxom in treatment of recurrent urinary tract infections in girls]. / Kliniczna ocena preparatu Uro-Vaxom w leczeniu nawracajacych zakazen ukladu moczowego u dziewczynek.

Uro-Vaxom was used in the treatment of recurrent urinary tract infections in 28 girls. Most of them (27/28) tolerated the drug very well, no side effects were observed. We stopped administration of the Uro-Vaxom in one girl during the first month of treatment because of vomiting. Uro-Vaxom efficiency was, therefore, evaluated in 27 girls. Uro-Vaxom was found to be a valuable drug, supplementing antibiotic therapy in recurrent urinary tract infections caused by E. coli.

[The concentration of uric acid in twenty-four hour urine collections of health children in various age groups]. / Stezenie kwasu moczowego w zbiórkach dobowych moczu u dzieci zdrowych, w róznych grupach wieku.

The concentration of uric acid in a 24-hour urine of 94 healthy children was determined. The concentrations of uric acid and numbers of children of various groups of age are presented in table I and II.

[Diurnal urinary excretion of oxalic acid in healthy children of different age groups]. / Dobowe wydalanie kwasu szczawiowego w moczu u zdrowych dzieci w róznych grupach wieku.

The oxalic acid concentration in 24 hour urine of 94 healthy children, aged 1 to 18 years, were determined. The colorimetric method of Slodgkinson and Williams in modification of Rozentall was used to determine the oxalic acid concentration. Obtained results were analysed in following age groups: 1-3 years, 3-6 years, 9-14 years and 14-18 years. Table I shows the results of determinations of oxalic acid concentration in 24 hour urine and numbers of children in age groups.

[Urinary tract infections and urolithiasis]. / Zakazenie dróg moczowych a kamica ukladu moczowego.

100 cases of urolithiasis in children treated in Pediatric Clinic of National Research Institute of Mother and Child in the period of 1976-1979 were analized . In 93 children the cause of urolithiasis was established. The most of them (31%) are cases of infection induced urinary stones. Among other reasons of urolithiasis the most common are: metabolic reasons in 26%, probably metabolic reasons in 13%, idiopathic oxalic lithiasis in 17% and others in 6%. At the moment of urolithiasis diagnosis in 94 children bacteriological investigations were done. In 54 cases, i.e. 57,4% infections of the urinary tract were found. 57,8% of boys and 62,2% of girls had urinary tract infections. The most frequent bacteria was urease producting Proteus sp. During 3 years of observation urinary tract infections in 67 children were found. Among bacteria causing the reinfections the most frequent were: Pseudomonas aeruginosa (25,4%), Klebsiella sp. (22,4%), Proteus sp. (19,9%) and E. coli (15%). In 9 cases the bacteriological analysis of removed stones were done. In 2 cases bacteria causing the infection were isolated from the stones, since they were not present in urine any more.

[Urinary calculi in children]. / Kamica ukladu moczowego u dzieci.

Urolithiasis in children is a very important problem from the theoretical as well as from practical point of view. Better knowledge of its metabolic basis may allow to move the central treatment from surgical to prophylactic methods. The study presents modern view points on mechanisms for concrements sedimentation and actual data on metabolic disturbances in calcium, oxalates, purines, xanthines and cystine and their relations to urolithiasis and urinary tract infection.

[Metabolic etiology of urinary calculi in children]. / Przyczyny metaboliczne kamicy ukladu moczowego u dzieci.

The analysed material includes 100 children with urolithiasis treated in the Pediatric Clinic of the National Research Institute of Mother and Child in Warsaw between 1976 and 1978. Patients' age was from 3 months to 18 years. The analysed group included 51 boys and 49 girls. Urinary tract infection was found in 54 cases, i.e. 57,4% of the analysed material. The most common bacterial strains were those producing urease. They were detected in 48 children i.e. 88,9% of cases with urinary tract infection. Mostly these were bacteria of Proteus group--sporadically Pseudomonas aeruginosa and Staphylococcus albus. In the analysed patients urinary tract obstruction was observed in 36 children, i.e. 36% of cases. In 77% of the analysed material, localization of concrements was in upper urinary tract in 19% in the ureters and in 4% in the lover urinary tract. While in adult patients the most common compound of urinary stones was calcium oxalate, in children the most common stone compounds were phosphates (found in 38 cases i.e. 58,4% of the analysed material). The second frequent compound was oxalate found in 20 cases (30,7%). Less frequent compounds were uric acid and cystine. Performed study allowed to establish the cause of urolithiasis in 93 out of 100 examined children. Metabolic reasons of urolithiasis were found in 26 cases, i.e. 26% of the analysed material. They were as follows: idiopathic hypercalciuria--12 cases, uric acid urolithiasis--8 cases, primary hyperoxaluria--3 cases, cystinuria--2 cases, and incomplete acidosis of distal renal tubuli--1 case. Urolithiasis of probably metabolic origin was detected in 13 children (13%). Other reasons of urolithiasis in children were: infection (31%), idiopathic urolithiasis (17%) and others (6%). In 7 cases the reason of urolithiasis was not established.