Effect of magnetic resonance imaging in liver metastases.

This letter to the editor is a commentary on a study titled "Liver metastases: The role of magnetic resonance imaging." Exploring a noninvasive imaging evaluation system for the biological behavior of hepatocellular carcinoma (HCC) is the key to achieving precise diagnosis and treatment and improving prognosis. This review summarizes the role of magnetic resonance imaging in the detection and evaluation of liver metastases, describes its main imaging features, and focuses on the added value of the latest imaging tools (such as T1 weighted in phase imaging, T1 weighted out of phase imaging; diffusion-weighted imaging, T2 weighted imaging). In this study, I investigated the necessity and benefits of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid for HCC diagnostic testing and prognostic evaluation.

A simple and green method for direct determination of hydrogen peroxide and hypochlorite in household disinfectants based on personal glucose meter.

A convenient and green method was developed using a personal glucose meter (PGM) for direct determination of hydrogen peroxide and hypochlorite in household disinfectants based on the acetylthiocholine iodide (ATCI)-mediated reaction. In this method, acetylcholinesterase catalyzes the hydrolysis of ATCI to generate thiocholine iodide, which can trigger the reduction of K3[Fe(CN)6] to K4[Fe(CN)6] and generate a PGM detectable signal. When the hydrogen peroxide or hypochlorite is pre-incubated with the ATCI, the yield of thiocholine will be decreased because the iodine molecules can initiate the oxidation of thiocholine to disulphides, leading to a lower PGM readout. Thus, the hydrogen peroxide or hypochlorite can be directly quantified by PGM as simple as detecting glucose in blood. After being systematically investigated, the optimum conditions of the PGM method are as follows: 5.0 min of enzymatic reaction time, 6.0 mM final concentration of ATCI solution, and 10.0 min of reaction time between ATCI/H2O2 and thiocholine. Moreover, the recoveries of hydrogen peroxide in real sample spiked with three different concentrations (final concentrations of 5.0, 10.0, and 20.0 mM) are in the range of 96.3-108.4%. The recoveries of hypochlorite in real sample spiked with three different concentrations (final concentrations of 1.0, 5.0, and 10.0 mM) are in the range of 99.4-117.0%. These results indicate that the developed method can be employed for the detection of hydrogen peroxide and hypochlorite in household disinfectants.