Sialoadenitis aguda por administración de contraste yodado / Acute sialadenitis by iodine contrast medium administration

La sialoadenitis aguda es una reacción adversa muypoco frecuente a la administración de contraste yodado,que causa una inflamación autolimitada de las glándulassalivales. Su patogenia no está bien establecida, aunque la insuficiencia renal puede ser un factor de riesgo.El diagnóstico es inicialmente clínico, y debe realizarsediagnóstico diferencial con angioedema, infecciones y litiasis. Ningún tratamiento o profilaxis ha demostrado beneficio hasta el momento. Aunque tiene buen pronóstico,en algunos casos se han descrito complicaciones.Presentamos el caso de un varón de 68 años que presentó inflamación de las glándulas salivales submandibulares tras la realización de una tomografía computariza-da abdominal con administración de contraste yodado.Dado el uso creciente de contrastes yodados en pruebasde imagen y técnicas intervencionistas, es importante conocer posibles reacciones adversas como esta entidad.(AU)

Acute iodide sialadenitis is a rare adverse reactionto iodinated contrast that causes self-limited salivarygland swelling. Its pathogenesis is still unclear, althoughkidney failure may be a risk factor. The diagnosis isinitially clinical but angioedema, infections and lithiasis should be included in the differential diagnosis. Notreatment or prophylaxis was proven to be beneficial.Although its prognosis is benign, associated complications have been reported.We report a case of 68-year-old man with swelling ofthe submandibular salivary glands after the administration of iodine-based contrast media during an abdomi-nal computed tomography examination. Because of thewidespread use of iodinated contrast enhanced imaging and interventional techniques, clinicians should beaware of this issue.(AU)

[Acute sialadenitis by iodine contrast medium administration].

Acute iodide sialadenitis is a rare adverse reaction to iodinated contrast that causes self-limited salivary gland swell-ing. Its pathogenesis is still unclear, although kidney failure may be a risk factor. The diagnosis is initially clinical but angioedema, infections and lithiasis should be included in the differential diagnosis. No treatment or prophylaxis was proven to be beneficial. Although its prognosis is benign, associated complications have been reported. We report a case of 68-year-old man with swelling of the submandibular salivary glands after the administration of iodine-based contrast media during an abdominal computed tomography examination. Because of the widespread use of iodinated contrast enhanced imaging and interventional techniques, clinicians should be aware of this issue.

Linfoma de Burkitt abdominal en un adolescente / Abdominal burkitt lymphoma in an adolescent

Se describe el caso clínico de un adolescente con un linfoma de Burkitt que debutó con dolor abdominal agudo. El tumor aumentó de tamaño rápidamente, se localizó mediante tomografía computarizada y se confirmó mediante estudio de la médula ósea. Se aplicaron dos protocolos quimioterápicos distintos, debido a la mala evolución, pero sin resultado satisfactorio. Se hacen unas consideraciones sobre el diagnóstico diferencial, especialmente con otros tumores primarios infantiles y procesos no neoplásicos

We report the case of a male adolescent affected by Burkitt Lymphoma which presented as acute abdominal pain and rapid growth mass. It was characterized by computed tomography and diagnose was confirmed by bone marrow study. Two different chemotherapic regimens were used because of unfavourable evolution, but they were not successful. We consider some other causes of abdominal bulky in childhood, especially primary tumours and non tumoural diseases

[Chimerism: origin and medical implications]. / Quimerismo: origen e implicaciones médicas.

The organism whose cells come from different individuals is called chimera. It is frequently observed in nature: pregnancy, organ transplantation or transfusion are considered chimeric cell sources. It has been involved in autoimmune diseases development such as scleroderma, because of similarities between it and graft versus host disease, long term persistence of fetal cells in women and the finding of greater number of chimeric cells in affected women than healthy ones. It is not strictly a disease but might be considered helpful in non-invasive prenatal diagnosis and damaged organs regeneration.

Quimerismo: origen e implicaciones médicas / Chimerism: origin and medical implications

Se denomina «quimera» al organismo formado por células procedentes de distintos individuos. Se trata de un fenómeno frecuente en la naturaleza que puede aparecer tras la gestación, un trasplante de órganos o una transfusión. Se ha relacionado con el desarrollo de enfermedades autoinmunes (EAI), concretamente la esclerodermia. La hipótesis que relaciona el quimerismo con las EAI surge de distintas observaciones, como la similitud de la esclerodermia con la enfermedad injerto contra huésped, la persistencia de células quiméricas en el tiempo y el hallazgo de mayor número de células quiméricas en mujeres afectas que en sanas. Este fenómeno no se asocia necesariamente a enfermedad, y podría ser de utilidad en diagnóstico prenatal e incluso estar implicado en la regeneración de órganos dañados

The organism whose cells come from different individuals is called chimera. It is frequently observed in nature: pregnancy, organ transplantation or transfusion are considered chimeric cell sources. It has been involved in autoimmune diseases development such as scleroderma, because of similarities between it and graft versus host disease, long term persistence of fetal cells in women and the finding of greater number of chimeric cells in affected women than healthy ones. It is not strictly a disease but might be considered helpful in non-invasive prenatal diagnosis and damaged organs regeneration

[Abdominal Burkitt lymphoma in an adolescent]. / Linfoma de Burkitt abdominal en un adolescente.

We report the case of a male adolescent affected by Burkitt Lymphoma which presented as acute abdominal pain and rapid growth mass. It was characterized by computed tomography and diagnose was confirmed by bone marrow study. Two different chemotherapic regimens were used because of unfavourable evolution, but they were not successful. We consider some other causes of abdominal bulky in childhood, especially primary tumours and non tumoural diseases.