RESUMEN
Allergic reactions occurring after tattooing, especially after the use of red tattoo ink ingredients are relatively rare. We report a painful skin reaction occurring 6 months after the tattoing of the right lower extremity in a 30-year-old female patient. Pathohistological and immunchemical results confirmed a pseudolymphoma. Only the tangential excision of the affected areas led to a sufficient healing process. Split thickness skin grafts were used for defect coverage. 2 years later, the patient was still pain free and the wounds had healed completely without any irritation.
Asunto(s)
Colorantes/efectos adversos , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/inmunología , Reacción a Cuerpo Extraño/diagnóstico , Reacción a Cuerpo Extraño/inmunología , Seudolinfoma/diagnóstico , Seudolinfoma/inmunología , Tatuaje/efectos adversos , Adulto , Dermatitis Alérgica por Contacto/patología , Femenino , Reacción a Cuerpo Extraño/patología , Humanos , Pierna , Seudolinfoma/patología , Piel/efectos de los fármacos , Piel/patologíaRESUMEN
Regions of the promoter and exons 5-8 of the tumour suppressor gene p53 were analysed in 25 cases of sporadic bovine leucosis. The study included 17 cases of juvenile leucosis, five cases of adult leucosis and three cases of skin leucosis. Exon 2 of tumour suppressor gene p16 was also investigated in the same samples. No sequence variations were present in the analysed areas of the genes. In p53, this fact represents a clear difference in comparison with enzootic bovine leucosis. In p16, no comparative data are available.
Asunto(s)
Leucosis Bovina Enzoótica/genética , Genes p16/genética , Genes p53/genética , Secuencia de Aminoácidos , Animales , Secuencia de Bases , Bovinos , Infecciones por Deltaretrovirus/genética , Infecciones por Deltaretrovirus/veterinaria , Exones/genética , Datos de Secuencia Molecular , Mutación , Regiones Promotoras Genéticas/genéticaRESUMEN
Spontaneous splenic rupture is a rare cause of non-traumatic haemorrhage and is of infectious origin in most instances. We present a patient under treatment for abdominal manifestations of metastatic malignant melanoma who developed signs of haemorrhagic shock and where, upon emergency laparotomy, metastases were found to have caused rupture of the spleen. The patient recovered after splenectomy and was continued on systemic chemoimmunotherapy. One year after the incident he died of cerebral metastases.