Asunto(s)
Anisakis , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Profesional/diagnóstico , Dermatosis de la Mano/diagnóstico , Adulto , Animales , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Diagnóstico Diferencial , Dermatosis Facial/inducido químicamente , Dermatosis Facial/diagnóstico , Peces/parasitología , Dermatosis del Pie/inducido químicamente , Dermatosis del Pie/diagnóstico , Dermatosis de la Mano/inducido químicamente , Humanos , Larva , Masculino , Goma/efectos adversos , Pruebas CutáneasAsunto(s)
Amoxicilina/efectos adversos , Dermatitis Profesional/diagnóstico , Dermatosis Facial/diagnóstico , Penicilinas/efectos adversos , Urticaria/diagnóstico , Adulto , Dermatitis Profesional/etiología , Diagnóstico Diferencial , Dermatosis Facial/etiología , Humanos , Masculino , Enfermería , Pruebas Cutáneas , Urticaria/etiologíaRESUMEN
Patients allergic to fish usually present with skin reactions after handling raw fish. Less frequently, these reactions are seen without symptoms after oral intake, often in chefs and food handlers. We have attempted to explain the skin selectivity of such reactions in a 36-year-old woman with contact urticaria after handling raw fish. We obtained aqueous extracts of raw and cooked fish (sole and hake) for in vivo (prick test) and in vitro (SDS-PAGE, IgE Immunoblot) tests. Prick-by-prick test, 20-min closed patch test, rub test with fresh and cooked fish (sole, hake and cod) and specific IgE (CAP-system) to sole, cod and hake were performed. The strength of positive reaction to raw fish was greater than to cooked fish on both prick and prick-by-prick testing. Rub tests showed positive responses only to raw fish. Specific IgEs to sole (45 KU/l), hake (66.9 KU/l) and cod (18.7 KU/l) were obtained. IgE immunoblot recognized 3 antigens of 25, 48, 56 kDa in raw sole and 1 of 42 kDa in raw hake extracts. No IgE binding was observed with the cooked extracts or control sera. Our findings strongly suggest a Type-I hypersensitivity to fish. Immunoblot analyses demonstrated a loss of specific IgE binding to cooked extracts. We have reported a case of contact urticaria caused by heat-sensitive raw-fish allergens in a patient who probably became sensitized via the cutaneous route.
Asunto(s)
Alérgenos/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Peces , Urticaria/etiología , Adulto , Animales , Femenino , Calor , Humanos , Pruebas CutáneasAsunto(s)
Alérgenos/efectos adversos , Proteínas Contráctiles , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Profesional/diagnóstico , Frutas/efectos adversos , Dermatosis de la Mano/diagnóstico , Proteínas de Microfilamentos/efectos adversos , Adolescente , Reacciones Cruzadas , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Diagnóstico Diferencial , Manipulación de Alimentos , Dermatosis de la Mano/etiología , Humanos , Masculino , Profilinas , Pruebas CutáneasAsunto(s)
Cosméticos/efectos adversos , Dermatitis Alérgica por Contacto/epidemiología , Nitrilos/efectos adversos , Conservadores Farmacéuticos/efectos adversos , Adolescente , Adulto , Anciano , Dermatitis Alérgica por Contacto/etiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas del Parche , España/epidemiologíaRESUMEN
Cyanoacrylates are widely used in adhesive techniques. Cyanoacrylate adhesives differ physically for the different needs of application, and chemically in function of the size of ester molecules. A 40-year-old man employed at the National Mint and Stamp factory presented with hyperkeratotic lesions on the fingers of the right hand. His job consisted of fixing microchips to plastic phone cards with Loctite Series 414. Patch testing confirmed sensitivity to cyanoacrylates. After the diagnosis of allergic contact dermatitis was established, the patient, to be cured of the dermatitis, changed his workplace 2 months later.
Asunto(s)
Adhesivos/efectos adversos , Cianoacrilatos/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Dermatosis de la Mano/inducido químicamente , Adulto , Humanos , Queratosis/inducido químicamente , Masculino , Metacrilatos/efectos adversos , Pruebas del Parche , Ácidos Polimetacrílicos/efectos adversosRESUMEN
An unusual cutaneous eruption of the feet and lower limbs induced by ultraviolet radiation in a 30-year-old caucasian man is presented. Previous reports in the literature and the present case indicate that sunlight and UV radiation may provoke fixed eruptions themselves without drug exposure.
Asunto(s)
Exantema/etiología , Exantema/patología , Rayos Ultravioleta/efectos adversos , Adulto , Dermatitis Fototóxica/diagnóstico , Dermatitis Fototóxica/etiología , Dermatitis Fototóxica/patología , Diagnóstico Diferencial , Exantema/diagnóstico , Dermatosis del Pie/etiología , Dermatosis del Pie/fisiopatología , Humanos , Dermatosis de la Pierna/etiología , Dermatosis de la Pierna/fisiopatología , MasculinoRESUMEN
We report the patch test results of 449 construction workers who came as patients to the Occupational Dermatology Service of the Instituto Nacional de Medicina y Seguridad del Trabajo in Madrid between 1989 and 1993. 90.8% of them were patch tested, because they had cutaneous lesions or a clinical history suggestive of occupational dermatitis. 65.5% (268) of those patch tested showed one or more reactions connected with their work. Chromate at 42.1% was the main allergen, followed by cobalt, 20.5%, nickel, 10%, and epoxy resin, 7.5%. 25.9% (106) of patients showed sensitization to rubber components, the majority at 23.7% to thiuram mix, with TETD being the main allergen.
Asunto(s)
Cromatos/efectos adversos , Cobalto/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Níquel/efectos adversos , Exposición Profesional/efectos adversos , Goma/efectos adversos , Adolescente , Adulto , Anciano , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Profesional/diagnóstico , Humanos , Masculino , Persona de Mediana Edad , Pruebas del Parche , Estudios Retrospectivos , EspañaAsunto(s)
Contaminantes Ocupacionales del Aire/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Eccema/inducido químicamente , Famotidina/efectos adversos , Adulto , Industria Farmacéutica , Famotidina/síntesis química , Femenino , Humanos , Masculino , Persona de Mediana EdadRESUMEN
The use of new products in building and public works is increasing, among them being special floor coverings containing epoxy resins and derivatives. These are used principally in heavily frequented areas, such as shopping precincts, hospitals, civic centres, etc., due to their high resistance to wear and tear, environmental factors, etc. In the last 2 years, we have studied 15 cases of men sensitized to epoxy resin, or derivatives, who worked with special floorings. Speed of sensitization, severity of lesions, and localization to the hands, face and legs were characteristic.
Asunto(s)
Materiales de Construcción/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Resinas Epoxi/efectos adversos , Pisos y Cubiertas de Piso , Adulto , Humanos , Masculino , Persona de Mediana EdadAsunto(s)
Contaminantes Ocupacionales del Aire/efectos adversos , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/etiología , Numismática , Filatelia , Adulto , Compuestos de Bencidrilo , Resinas Epoxi/efectos adversos , Femenino , Humanos , Masculino , Pintura/efectos adversos , Impresión , EspañaRESUMEN
BACKGROUND: Rubber additives, mainly vulcanizers and antioxidants, are increasingly a cause of contact dermatitis. OBJECTIVE: The aim of the present study was to determine the frequency of type IV allergy to rubber additives. METHODS: Seven thousand patients seen during a 10-year period were evaluated. Of them, 4680 were patch tested with the standard series recommended by the Spanish Group for Research of Contact Dermatitis (GEIDC) and a series of individual rubber additives. RESULTS: A total of 686 patients (14.7% of those patch tested) had one or more positive reactions to rubber additives. Of these, 582 (84.8%) were men and 104 (15.2%) were women. The incidence of rubber sensitization was especially high among construction workers (47.0%). CONCLUSION: Rubber additives are a common cause of occupational contact dermatitis, particularly in construction workers. We postulate that rubber gloves and boots (utilized to avoid contact with sensitizing substances) themselves may be a common cause of contact dermatitis. The high incidence of allergy to some rubber additives, such as thiurams and carbas, indicates that their replacement by other less sensitizing vulcanizers is advisable.