Localized genitourinary tract Aspergillus infection in an immunocompetent patient: Bladder and epidydimal aspergillosis.

Invasive bladder Aspergillosis has only been reported in six publications so far. A 74-year-old male, presented to the emergency department with fever, abdominal pain, and right testicular enlargement. Abdominal computed tomography concluded a bladder tumor and testicular ultrasound reported right epididymitis. Cystoscopy showed a bladder fungal mass, which was extracted with cystotomy. Pathological findings reported Aspergillus species. The patient was successfully treated with 4-week oral Isovuconazole. The first bladder Aspergillosis was published in 1978. The most recent case was published in 2020. Aspergillosis infection is extremely rare disease, treatment with Isavuconazole is efficient.

[Bronchogenic cysts. Importance of infection in adults. Study of 12 cases]. / Quistes broncogénicos. Importancia de la infección en adultos. Estudio de 12 casos.

BACKGROUND: Bronchogenic cyst is a rare congenital malformation and commonly located in the mediastinum and lung parenchyma. OBJECTIVE: To determine the clinical characteristics of the patients with diagnosis of bronchogenic cysts, their location and the infectious bacteria when the cysts are infected. The cases were collected from 1 January 2005 to 1 January 2013, in a third level hospital. MATERIAL AND METHODS: The cases with bronchogenic cysts resected by thoracotomy were confirmed by histological study. Age, sex, admission diagnosis, location, size, imagenologic studies, and bacteriological cultures were evaluated. RESULTS: Of the 12 cases with diagnosis of bronchogenic cysts surgically resected by thoracotomy, six were male and six female, with 50% located in lung parenchyma and 50% in mediastinum, one of the latter was para-oesophageal. Bacteriological study of the cystic content demonstrated bacterial infection in seven (58%) cases. CONCLUSIONS: Bronchogenic cysts are rare congenital benign lesions. They must be resected because their content might be infected. The histopathology study is necessary to confirm the diagnosis, together with bacteriological examination. Thoracotomy is a safe procedure to resect bronchogenic cysts.

[Solitary fibrous tumor. Clinic and pathological study of 16 cases].

BACKGROUND: Solitary fibrous tumor (SFT) is a localized fibrous mesothelioma and was originally described as a benign pleural lesion. It is a mesenchymatous lesion that has been found in different structures and tissues of the human organism. It originates from a stromal fibroblastic cell positive to CD4. We undertook this study to determine the clinical and histopathological characteristics of SFT found from January 1, 2002--January 31, 2010 in a concentrated third-level general hospital in Mexico City. METHODS: We present 16 resected cases of different localizations: three pleural, three mediastinal, three lung, two oral cavity, one nasopharyngeal, one in the lateral aspect of the neck, one kidney, one paratesticular and another in the crural region. All were studied with hematoxylin and immunoperoxidase. RESULTS: There was similar affection in both genders. Mean age was 51 years (range: 43-81 years). Two pleural cases presented recurrence and one had hypoglycemia but none demonstrated metastases. No deaths were registered during a mean follow-up of 18 months. Histological pattern corresponded to a fusocellular growth that coincided with hemangiopericytoid zones in five cases and sarcomatoid in four. These cases were considered as mixed. All were positive to vimentin. CONCLUSIONS: Definitive diagnosis must be made by immunoperoxidase. Immediate treatment is surgical resection; relapses.

Melanoma osteogénico (melanoma con metaplasia osteocartilaginosa). Presentación de un caso y revisión de la literatura / Osteogenic melanoma (melanoma with osteocartilaginous metaplasia). Presentation of a case and literature review

El melanoma maligno es un tumor que presenta numerosos patrones histológicos que pueden semejar carcinoma o diferentes tipos de sarcoma de alto o bajo grado de malignidad. Una de estas variantes corresponde al melanoma osteogénico, donde se encuentra metaplasia osteocartilaginosa. Se han descrito con diferenciación fibroblástica (melanoma desmoplásico), con diferenciación a células de Schwann (melanoma neurotrópico) y éstos a su vez con diferenciación lipoblástica, rabdomioblástica, con células ganglionares, y con estructuras seudomeissnerianas, así como con degeneración mixoide y de células redondas. En la literatura médica, hasta la fecha han sido informados 17 casos de melanomas osteogénicos, 14 en la piel y tres en mucosas.

Paragangliomas: estudio clinicopatológico de 25 casos / Paragangliomas: clinico-pathological study of 25 cases

Se notifica una serie de 25 paragangliomas extraadrenales, de los cuales 20 se originaron en el cuerpo carotídeo y los otros cinco en el ganglio nodoso del vago, glomus carotídeo, glomus timpánico y nasofaríngeo; 22 casos correspondieron a mujeres; la edad promedio fue de 52 años. Los casos fueron de la variedad esporádica sin antecedentes familiares. Todos los pacientes fueron operados; cuatro se complicaron con sangrado masivo, uno con choque hipovolémico. Otro desarrolló infarto cerebral por ligadura de la carótida primitiva. Dos pacientes tuvieron complicaciones por lesiones de pares craneales. Hubo una recurrencia ocho años después de la cirugía. Ningún caso desarrolló metástasis