Asunto(s)
Papiledema/diagnóstico por imagen , Papiledema/etiología , Leucemia-Linfoma Linfoblástico de Células Precursoras/complicaciones , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico por imagen , Niño , Humanos , Masculino , Oftalmoscopía , Papiledema/patología , Leucemia-Linfoma Linfoblástico de Células Precursoras/patología , Índice de Severidad de la Enfermedad , Agudeza VisualAsunto(s)
Enfermedades de la Coroides/diagnóstico , Lupus Eritematoso Sistémico/diagnóstico , Enfermedades de la Retina/diagnóstico , Corticoesteroides/administración & dosificación , Adulto , Esquema de Medicación , Femenino , Angiografía con Fluoresceína , Humanos , Lupus Eritematoso Sistémico/tratamiento farmacológico , Enfermedades de la Retina/tratamiento farmacológico , Epitelio Pigmentado de la Retina/efectos de los fármacos , Epitelio Pigmentado de la Retina/patología , RetinoscopíaAsunto(s)
Cámara Anterior , Cobre , Lesiones de la Cornea/diagnóstico , Cuerpos Extraños en el Ojo/diagnóstico , Lesiones Oculares Penetrantes/diagnóstico , Adulto , Cámara Anterior/patología , Cámara Anterior/cirugía , Profilaxis Antibiótica , Lesiones de la Cornea/cirugía , Cuerpos Extraños en el Ojo/cirugía , Lesiones Oculares Penetrantes/cirugía , Humanos , Masculino , Paracentesis , Lámpara de HendiduraAsunto(s)
Amiloidosis Familiar/diagnóstico , Distrofias Hereditarias de la Córnea/diagnóstico , Anciano , Amiloidosis Familiar/genética , Amiloidosis Familiar/patología , Antígenos de Neoplasias/genética , Moléculas de Adhesión Celular/genética , Distrofias Hereditarias de la Córnea/genética , Distrofias Hereditarias de la Córnea/patología , Humanos , MasculinoRESUMEN
PURPOSE: To assess the prevalence, morphology and distribution of retinal hemorrhages in healthy newborns and their relationship to neonatal, maternal and obstetrical factors, and to determine their natural history. PATIENTS AND METHODS: The present study prospectively included 2,031 consecutive healthy newborns. Indirect ophthalmoscopy was performed within 24 hours after birth in all newborns. Infants with retinal hemorrhages were reexamined weekly until the hemorrhage resolved. Annual ophthalmologic follow-up was also scheduled in these children. Neonatal, maternal and obstetric parameters were analyzed in all newborns and compared between newborns with retinal hemorrhages and those without retinal hemorrhages. RESULTS: 31.8 % of newborns exhibited retinal hemorrhages. 72.6 % of hemorrhages were bilateral. They tended to be localized around the optic discs and in the posterior pole, but their distribution was variable. Retinal hemorrhages were of variable shapes. The prevalence of retinal hemorrhages was higher in newborns delivered with vacuum-assisted extraction (38 %, P<0.001), intermediate during normal vaginal delivery (32.6 %, P<0.001) and lower with cesarean section (20.8 %). Comparative analysis between elective cesarean section and emergency cesarean showed a higher incidence of retinal hemorrhages in the emergency cesarean group (P=0.006). On multivariate analysis, vacuum-assisted delivery was the only factor associated with a higher prevalence of retinal hemorrhages in newborns (P=0.045). Two thirds of hemorrhages had disappeared by one week after birth. Retinal hemorrhages had resolved in all newborns within four weeks. CONCLUSION: Birth-related retinal hemorrhages are common (1/3 of our newborns). Vacuum-assisted delivery is the main risk factor in this study. All hemorrhages resolved by one month of age. These findings may help in differential diagnosis with shaken baby syndrome.