Clinical curative effect of fuzi-cake-separated moxibustion for preventing dysuria after operation for lower limb fracture.

OBJECTIVE: To assess the clinical curative effect of fuzi-cake-separated moxibustion at Zhongji (CV 3) and Guanyuan (CV 4) for preventing dysuria after internal fixation of lower limb fractures. METHODS: Sixty patients conforming to the inclusion standards were randomly divided into a treatment group (n = 30) and a control group (n = 30). Fuzi-cake-separated moxibustion was performed at Guanyuan (CV 4) and Zhongji (CV 3), 20 min at a time, twice a day, for 3 days before operation in the treatment group. No fuzi-cake-separated moxibustion was performed in the control group. After treatment, the score for symptoms of first urination, urinary time, urinary volume, 24 h remaining urinary volume, incidence of uroschesis, and rate of controlling dysuria were compared to evaluate the curative effect of preventing post-operative dysuria. RESULTS: The score for symptoms of first urination, 24 h remaining urinary volume (maximum 120 mL vs 250 ml, and less than 10 ml in 24 cases vs 15 cases), and the rate of controlling dysuria (83.34% vs 30%) were significantly better (P < 0.05, P < 0.05, and P < 0.001, respectively) in the treatment compared with the control group. There was no statistical difference (P > 0.05) between the two groups in first post-operative urinary time, urinary volume, or incidence of 24 h uroschesis. CONCLUSION: Fuzi-cake-separated moxibustion at Zhongji (CV 3) and Guanyuan (CV 4) can better prevent post-operative dysuria, effectively promote the functional restoration of the urinary bladder, and control the incidence of post-operative dysuria.

Assessment of intrarenal oxygenation in renal donor with blood oxygenation level-dependent magnetic resonance imaging.

OBJECTIVE: To examine change of the apparent relaxation rate R2* values in living kidney donors after uninephrectomy using blood oxygenation level-dependent magnetic resonance imaging. METHODS: Between July 2011 and January 2012, 45 kidney donors were enrolled into this study. Blood oxygenation level-dependent magnetic resonance imaging scanning was performed before surgery, 3 and 7 days postoperatively. Participants were followed up for 1 year. RESULTS: The R2* values in medulla (mR2*) were significantly greater than that of cortex (cR2*), both in resected kidney and remaining one. cR2* values of the remaining kidney was 17.52 ± 1.36 s(-1) and then decrease significantly by 8.97% to 15.95 ± 1.14 s(-1) at 3 days (P <.001) and by 7.82% to 16.15 ± of 1.05 s(-1) at 7 days. No significant modification occurred in mR2* after surgery. Multivariate regression analysis showed that the decrease in cR2* values of the remaining kidney was positively associated with sex (r = 0.418), body surface area (r = 0.307), and preoperative cR2* values (r = 0.659). Comparing with glomerular filtration rate at 7 days, a further increment in the glomerular filtration rate was noted at 1 year in patients with cR2* values decrease of ≥ 10% at 1 week (62.63 ± 11.69 vs 56.97 ± 7.51 mL/min/1.73 m(2), P = .02) but not in the other patients (66.43 ± 10.89 vs 62.78 ± 13.74, P = .064). CONCLUSION: Kidney donation will induce early, profound oxygenation modification within the renal cortex of the remaining kidney. Donors with cR2* value decrease of ≥ 10% at 1 week have a more favorable renal function compensation at 1 year.

The pre-transplant anemic condition is independent of long-term outcome in living-related kidney transplantation.

The relationship between pre-transplant Hemoglobin (Hb) concentration and long-term outcome of living-related kidney transplantation is far from well addressed. A retrospective cohort study was conducted by reviewing the medical profile of the patients who received living-related kidney transplantations at our center from January 2006 to January 2013. Patients were divided into two groups: high Hb group (≥10 g/dL) and low Hb group (<10 g/dL). Cox regression model was utilized to analyze the effect of pre-transplant hemoglobin concentration on the patient and graft survival. About 422 patients were of Hb level <10 g/dL (78.30 ± 14.18 g/dL), 280 were >10 g/dL (116.2 ± 14.43 g/dL) (p < 0.001). In a follow-up of 35.34 ± 18.12 months, we did not find any difference in serum creatinine between the two groups. Low Hb concentration is not associated with increased risk of developing DGF (HR = 1.186, 95% CI: 0.53-2.654), acute rejection (HR = 1.338, 95% CI: 0.919-1.947), overall infection (HR = 1.263, 95% CI: 0.847-1.885) nor perioperational infection (HR = 1.019, 95% CI: 0.513-2.026). Though we detected a trend that low Hb level group were of higher incidence of patient death and graft failure, the two groups did not differ significantly (2.38% vs. 0.71%, p = 0.096; and 4.04% vs. 2.14%, p = 0.165, respectively). Cox regression model revealed that pre-transplant Hb level <10 g/dL was independent of increased overall mortality (HR = 3.379; 95% CI: 0.706-17.172) and increased death censored allograft failure risk (HR = 1.556; 95% CI: 0.595-4.069). Pre-transplant Hb concentration <10 g/dL is independent of poor long-term outcome of living-related kidney transplantation.

Change in renal parenchymal volume in living kidney transplant donors.

PURPOSE: Uninephrectomy would induce compensatory hypertrophy in the remaining kidney. We investigated the relationship between changes in renal parenchymal volume (RPV) and renal function after nephrectomy in living kidney donors. METHODS: From July 2011 and January 2012, 45 kidney donors were enrolled in this study. Magnetic resonance scanning was performed before surgery, 3 and 7 days postoperatively, and RPV was calculated through disc summarize methods. Participants were followed up for 1 year. RESULTS: The RPV of the remaining kidney was 118.06 ± 23.51 cm(3) and then increased by 21.23 % to 143.13 ± 25.52 cm(3) at 3 days and by 24.17 % to 146.60 ± 25.86 cm(3) at 7 days. Multivariate regression analysis showed that preoperative RPV is positively related to its initial function (p = 0.037); the RPV at 7 days is directly related to its initial, preoperative size (p < 0.001). With respect to change in postoperative RPV, there is bigger gain in size in smaller kidneys (p = 0.005). The kidneys that has ≥20 % increase RPV after 7 days are more likely to show further increase in GFR at 1 year (p = 0.024). CONCLUSIONS: Uninephrectomy induced immediately increment in RPV of the remaining kidney. Donors with RPV increase of ≥20 % at 1 week have a more favourable renal function adaptation at 1 year.

[Observation on curative effect of thermal acupuncture needle muscular stimulation therapy for knee osteoarthritis patients].

OBJECTIVE: To observe the therapeutic effect of thermal acupuncture needle muscular stimulation for treatment of knee osteoarthritis patients. METHODS: A total of 120 outpatients with knee osteoarthritis were randomly and equally divided into control and treatment groups. Patients of the treatment group were treated by inserting the acupuncture needles into the attached sites of the quadriceps femoris, musculus vastus medialis, vastus lateralis, etc. around the knee joint. The needles were manipulated repeately till "Deqi", followed by attaching a piece of ignited moxa-roll (about 2 cm length) to the needle handle. The treatment was conducted once a week, 4 weeks altogether. Patients of the control group were treated by oral administration of Celebrex (a specific inhibitor of COX-2, 200 mg/time, once daily, 4 weeks together). The therapeutic effect was evaluated by using visual analogue scale (VAS), Lequesne Index (Chinese Version) of osteoarthritis after 4 weeks' treatment and 3 months after the treatment. RESULTS: After 4 weeks' treatment and 3 months after the treatment, the effective rates were 78.3% (47/60) and 81.7% (49/60) in the control group, and 96.6% (58/60) and 96.6% (58/60) in the treatment group, respectively, being significantly higher in the treatment group (P<0.05). Both VAS scores and Lequesne Indexes in the treatment group, and VAS scores in the control group were decreased significantly after 4 weeks' treatment and 3 months' follow-up (P<0.05). The effects of the treatment group were considerably superior to those of the control group (P<0.05). CONCLUSION: Thermal needle muscular stimulation therapy is effective for relieving knee osteoarthritis patients' symptoms of pain, knee-joint stiffness, swelling, walking capability, etc.