RESUMEN
The effects of surgical procedures on intestinal motility are still under debate. In order to quantify the effects of duodenotomy on duodenal motility, the present study used the electric impedance technique (IMP). Ten pigs (32-40 kg) were instrumented under general anaesthesia with a central venous catheter (CVC) and a percutaneous enterogastrostomy (PEG). Duodenal phases I-III and the duration of the migrating motor complex (MMC) were measured by an IMP catheter, which was introduced non-invasively into the proximal duodenum via the PEG by endoscopy, or through surgical placement in an invasive manner via duodenotomy. There were no significant differences in the length of interdigestive phases I-III between the groups. In tendency, pigs after laparotomy and duodenotomy demonstrated slightly prolonged median duration of phase I (P = 0.1) and phase III (P = 0.7), while phase II (P = 0.1) and the MMC cycle length (P = 0.6) seemed to be shortened as compared to pigs of the PEG group. In conclusion, simple laparotomy with duodenotomy did not affect the proximal duodenal motility activity measured by the impedance technique.
Asunto(s)
Duodeno/fisiología , Duodeno/cirugía , Motilidad Gastrointestinal/fisiología , Porcinos/fisiología , Porcinos/cirugía , Animales , Duodenoscopía/veterinaria , Impedancia Eléctrica , Gastroscopía/veterinaria , Ileus/etiología , Ileus/veterinaria , Masculino , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/veterinaria , Enfermedades de los Porcinos/etiologíaRESUMEN
To investigate the effects of propofol and fentanyl on the postprandial duodenal motility the intraluminal impedance technique was used. Six pigs were instrumented with a central venous catheter, a percutaneous enterogastrostomy (PEG), and an impedance catheter, which was introduced via the PEG into the duodenum through endoscopy. Over the following 3 d, duodenal motility was measured for 8-hour periods. Measurements were taken on each subject under 3 different sets of conditions: in the conscious unrestrained pig, during propofol sedation, and during sedation with propofol-fentanyl. Both, after morning feeding and during gastric nutrition via the PEG, duodenal feeding patterns and duodenal phase II of the migrating motor cycle were shortened during propofol and propofol-fentanyl sedation. In contrast, the duration of phase I was prolonged by propofol and propofol-fentanyl. In conclusion, either propofol or propofolfentanyl sedation shortens duodenal feeding patterns, as well as phase II of the migrating motor cycle.