RESUMEN
Echocardiography commonly represents the diagnostic clue in neonatal heart failure (HF). Congenital heart diseases are the most frequent causes of HF in this age group. Arterio-venous malformations are the most common noncardiac causes of HF. Normal cardiac structural findings on echocardiography require further investigations in order to exclude other causes of HF. We present three male patients admitted in the interval 2003-2007 with neonatal HF, systolic murmur, cardiomegaly, normal cardiac structure on echocardiography and intracranial bruit. All three cases were diagnosed with vein of Galen aneurysmal malformation (VGAM) by head ultrasound. According to age and malformation type, different presentation patterns were noticed: early neonatal intractable HF mimicking aortic coarctation, postnatal HF stabilized by drug treatment, and chronic HF in a VGAM with tendency to spontaneous regression. Both head ultrasound and cranial auscultation are mandatory in newborns or infants with no cardiac primary cause of HF.
Asunto(s)
Insuficiencia Cardíaca/diagnóstico , Insuficiencia Cardíaca/etiología , Aneurisma Intracraneal/diagnóstico , Malformaciones de la Vena de Galeno/diagnóstico , Diagnóstico Diferencial , Ecocardiografía Doppler , Insuficiencia Cardíaca/diagnóstico por imagen , Humanos , Recién Nacido , Aneurisma Intracraneal/complicaciones , Aneurisma Intracraneal/diagnóstico por imagen , Masculino , Malformaciones de la Vena de Galeno/complicaciones , Malformaciones de la Vena de Galeno/diagnóstico por imagenAsunto(s)
Síndrome de Inmunodeficiencia Adquirida/fisiopatología , Neumonía por Pneumocystis/fisiopatología , Síndrome de Inmunodeficiencia Adquirida/diagnóstico , Humanos , Lactante , Recién Nacido , Enfermedades del Prematuro/diagnóstico , Enfermedades del Prematuro/fisiopatología , Neumonía por Pneumocystis/patología , Estudios Retrospectivos , Timo/patologíaAsunto(s)
Infecciones Bacterianas/tratamiento farmacológico , Enfermedad Aguda , Amoxicilina/administración & dosificación , Combinación Amoxicilina-Clavulanato de Potasio , Niño , Preescolar , Ácidos Clavulánicos/administración & dosificación , Evaluación de Medicamentos , Humanos , Lactante , Recién Nacido , Inyecciones IntravenosasRESUMEN
Nine cases of congenital hemihypertrophy of an entire half of the body ("true" hemihypertrophy) were investigated in relation to literature data. The left side was more often affected (7:2) and the abnormality was more frequent in females (5:4). Associated abnormalities were present in all cases: a single abnormality in 3 cases (mental retardation, iris heterochromia and, respectively, left foot gigantism) and 3 to 13 abnormalities in the other 6 cases. Prominent hemiface, asymmetric macroglossia on the affected side, unequally developed breasts, unilateral gigantism of the foot, iris heterochromia, duplication of the renal pelvis, were considered important signs which easily draw attention. Out of nine cases investigated, three presented associated tumors: two tumors, one cerebral (malignant ependymoma) and the other hepatic (cavernous hemangioma) in one case, hepatoblastoma in another case, and multiple skin angiomas in the affected side of the third one. The case presenting two tumors had also the greatest number (twelve) of associated abnormalities.
Asunto(s)
Anomalías Múltiples , Adolescente , Adulto , Neoplasias Encefálicas/complicaciones , Preescolar , Anomalías del Ojo , Cara/patología , Hemiatrofia Facial/complicaciones , Femenino , Humanos , Hipertrofia , Lactante , Iris , Neoplasias Hepáticas/complicaciones , Macroglosia/complicaciones , Masculino , Escoliosis/complicaciones , Neoplasias Cutáneas/complicacionesRESUMEN
184 cases of acute poststreptococcal glomerulonephritis were investigated and six of these were associated with a peculiar, uncommon pneumonia, and another one had a lethal course. The clinicoradiological and especially pathological data summarized in this study attempt to demonstrate the individuality of this type of pneumonia. Pneumonia associated with acute poststreptococcal glomerulonephritis is similar or identical to rheumatic pneumonia. In both entities, pneumonia and pulmonary edema may and do coexist, and the differentiation of pneumonia from congestive heart failure is difficult and often impossible without pathological evidence. The most attractive pathogenic interpretation is the hypothesis of an immune mechanism in the induction of pneumonia. Authors attributed the lung changes, consecutive to a vascular damage, to a hypersensitivity phenomenon, with accumulation of fibrinogen in alveoli where it is converted to fibrin. Then, the hyaline membrane lining the alveoli, an important feature of pneumonia associated with glomerulonephritis is built up. It is, however, plausible that the effect of the immune reaction is associated with those of hydrosaline retention, arterial hypertension and congestive heart failure. Analogous to rheumatic pneumonia, the "peculiar pneumonia" associated with acute poststreptococcal glomerulonephritis should be named nephritic pneumonia.