[Retrospective clinical epidemiology research on a sample of 277 patients with viral hepatitis A, 20-70 aged, from the Suceava County, between 2001-2008]. / Cercetari clinico-epidemiologice, retroprospective, pe un lot de 277 bolnavi cu hepatita virala A, in vârsta de 20-70 ani, din judetul Suceava, in perioada 2001-2008.

UNLABELLED: Authors present some results of clinical epidemiological research carried out on a sample of 277 patients with viral hepatitis A (VHA), hospitalized in Suceava County, during 8 years. MATERIAL AND METHOD: An annual evolution of VHA incidence correlated with the epidemiological territorial situation was highlighted. RESULTS: Incidence of VHA in 20-40 age group represented 70.8%, and 33.5% in 20-25 age group. Diagnosis index was unfavourable with influence for interval of hospitalization over 21 days in 9.7% of cases. The VHA characteristic medium clinical form was kept in 80.1% of total patients. ASAT and ALAT levels were correlated with the clinical forms, age structure and early diagnosis difficulties.

[Retroprospective clinical epidemiological research on two samples of patients suffering from viral hepatitis A, assisted in specified services of Suceava and Botosani counties, between 1996 and 2007]. / Cercetari clinico-epidemiologice retroprospective, pe doua loturi de bolnavi cu hepatita virala A, asistati in serviciile de profil, din judetele Suceava si Botosani, in perioada 1996-2007.

UNLABELLED: Nowadays, researchers from various fields of study and geographical regions continue to pay attention to viral hepatitis A. Due to a resistant virus, with predominant enteral transmission, with endemic epidemic manifestations and a remarkable clinical polymorphism, affecting children especially, hepatitis A does not chronicize, but, in adults, it is responsible for forms with prolonged evolution and severe, sometimes. MATERIAL AND METHODS: Results of clinical epidemiological and laboratory studies carried on a sample of 10321 patients suffering from hepatitis A, from two lots: 5530, Suceava; 4791, Botosani; 5400, males; 4921 females; age from < 1 to = 55. RESULTS: In Suceava County, the hepatitis A incidence had epidemic values in 1996 (229%000) and 1997 (224%000). The most affected age groups, with hospitalized clinical forms, were 5-14 (42.3%) and 15-24 (24.9%). In Botosani County, epidemic peaks registered in 1999 (213%000), and inter-epidemic in the other years. The most affected age group was of 5-14, with 48.9% from all the admitted cases, but 52% from all cases belonged to age groups over 25.

[Assessments of retro-prospective epidemiologic research results regarding morbidity with viral hepatitis A in North-Eastern Moldavia, Romania, between 1970-2006]. / Evaluari asupra rezultatelor obtinute in cercetarile epidemiologice retroprospective privind morbiditatea prin hepatita virala A intr-o arie geografica din nord-estul Moldovei, România, in perioada 1970-2006.

UNLABELLED: Viral hepatitis A (VHA) maintains the first place among hepatitis with various etiologies, by high levels of morbidity, affecting mainly children and teenagers age groups and, sometimes, with major risks in adults and when over- and co-infected with other hepatitis viruses. It also is involved in travellers' and nosocomial diseases. MATERIAL AND METHOD: The assessment of VHA morbidity data highlighted that VHA registered yearly values between 106.8 and 307.1% hundred thousand inhabitants, both at the national and Suceava County levels, during the period 1970-1995. RESULTS: An important decline (24.8-47.8% hundred thousand) was registered, between 1996 and 2006. In the Suceava County, after the epidemic peaks from '80-'90 decade, with morbidity of 379.1% hundred thousand in 1989 and 331.8% hundred thousand in 1990, inter-epidemic and epidemic periods with reduced amplitude were registered. In 2006, morbidity reached a low value of 15.0% hundred thousand. CONCLUSION: Our study of "comparative epidemiology", on reported cases and those confirmed by hospitalisation, in the Suceava County, highlighted that the later proportion was under 50%, with an increase during 2005 (> 90%). A significant decrease in multi-annual trend of VHA morbidity registered for reported cases but not for those hospitalised.