1.
Clin Exp Allergy
; 54(1): 64-66, 2024 01.
Article
En
| MEDLINE
| ID: mdl-37940623
2.
J Pharmacol Sci
; 147(2): 208-210, 2021 Oct.
Article
En
| MEDLINE
| ID: mdl-34384569
Urinary tetranor-PGDM is a useful diagnostic biomarker for food allergy which often affects infants. We attempted to extract and measure urinary tetranor-PGDM absorbed in polymer of diapers. We applied CaCl2 to the collected polymer, determined the adequate time length of shaking the polymer to release urine, and measured tetranor-PGDM in the extracted urine. This procedure provided high linearity and recovery rate in tetranor-PGDM measurement. We also found that urinary tetranor-PGDM was stable for 24 h at 4°C in diapers. This method can be useful to monitor the food allergic condition of non-toilet trained children.
Diapers, Infant , Food Hypersensitivity/diagnosis , Liquid-Liquid Extraction/methods , Prostaglandin D2/analogs & derivatives , Biomarkers/urine , Calcium Chloride , Child, Preschool , Humans , Infant , Polymers , Prostaglandin D2/isolation & purification , Prostaglandin D2/urine , Temperature , Time Factors