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1.
J Am Med Inform Assoc ; 31(7): 1540-1550, 2024 Jun 20.
Artículo en Inglés | MEDLINE | ID: mdl-38804963

RESUMEN

OBJECTIVE: Predicting mortality after acute myocardial infarction (AMI) is crucial for timely prescription and treatment of AMI patients, but there are no appropriate AI systems for clinicians. Our primary goal is to develop a reliable and interpretable AI system and provide some valuable insights regarding short, and long-term mortality. MATERIALS AND METHODS: We propose the RIAS framework, an end-to-end framework that is designed with reliability and interpretability at its core and automatically optimizes the given model. Using RIAS, clinicians get accurate and reliable predictions which can be used as likelihood, with global and local explanations, and "what if" scenarios to achieve desired outcomes as well. RESULTS: We apply RIAS to AMI prognosis prediction data which comes from the Korean Acute Myocardial Infarction Registry. We compared FT-Transformer with XGBoost and MLP and found that FT-Transformer has superiority in sensitivity and comparable performance in AUROC and F1 score to XGBoost. Furthermore, RIAS reveals the significance of statin-based medications, beta-blockers, and age on mortality regardless of time period. Lastly, we showcase reliable and interpretable results of RIAS with local explanations and counterfactual examples for several realistic scenarios. DISCUSSION: RIAS addresses the "black-box" issue in AI by providing both global and local explanations based on SHAP values and reliable predictions, interpretable as actual likelihoods. The system's "what if" counterfactual explanations enable clinicians to simulate patient-specific scenarios under various conditions, enhancing its practical utility. CONCLUSION: The proposed framework provides reliable and interpretable predictions along with counterfactual examples.


Asunto(s)
Inteligencia Artificial , Infarto del Miocardio , Humanos , Infarto del Miocardio/mortalidad , Infarto del Miocardio/diagnóstico , Pronóstico , Masculino , Sistema de Registros , Femenino , República de Corea , Reproducibilidad de los Resultados , Anciano , Persona de Mediana Edad
2.
PLoS One ; 17(3): e0264032, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35294957

RESUMEN

People have their favorite type of sport, but such preferences tend to be shared for nearly a lifetime. How this preference persists remains inconclusive; hence, this study attempts to determine why people have different viewpoints on sports. It is reasonable to infer that these differences arise from differences in culture, occupation, and race. Therefore, we collected the following data and conducted research in Korea, the United States, and Japan, countries with various differences. The types of sports that people play were collected through surveys and comparisons among sports networks. Namely, "Sport Classification," "The K-12 Physical Education System (textbooks)," "Survey (actual physical activity)," "Simple Notification Service (SNS) Activity" have been examined to deduce the reason why any particular sport is played. Firstly, Korea, the United States, and Japan conduct different physical education courses. Hence, the results affect people's preferences. Secondly, what people post on SNS and their actual physical activities are different. Thirdly, the degree of connection between sports-type varied as well. Lastly, sports that serve the purpose of being regarded as hubs among sports-type were common in Korea, the United States, and Japan.


Asunto(s)
Educación y Entrenamiento Físico , Deportes , Curriculum , Ejercicio Físico , Humanos , Encuestas y Cuestionarios , Estados Unidos
3.
ACS Appl Mater Interfaces ; 10(4): 3810-3821, 2018 Jan 31.
Artículo en Inglés | MEDLINE | ID: mdl-29322769

RESUMEN

p-Type SnO thin films were deposited on a Si substrate by a cosputtering process using ceramic SnO and metal Sn targets at room temperature without adding oxygen. By varying the dc sputtering power applied to the Sn target while maintaining a constant radio frequency power to the SnO target, the Sn/O ratio varied from 56:44 to 74:26 at the as-deposited state. After thermal annealing at 180 °C for 25 min under air atmosphere using a microwave annealing system, the films were crystallized into tetragonal SnO when the Sn/O ratio increased from 44:56 to 57:43. Notably, the metallic Sn remained when the Sn/O ratio was higher than 55:45 at an annealed state. When the ratio was lower than 55:45 at the annealed state, the incorporated Sn fully oxidized to SnO, making the films useful p-type semiconductors, whereas the films became metallic conductors at higher Sn/O ratios. At the Sn/O ratio of 55:45 at the annealed state, the film showed the highest Hall mobility of 8.8 cm2 V-1 s-1 and a hole concentration of 5.4 × 1018 cm-3. Interestingly, the electrical conduction behavior showed trap-mediated hopping when the Sn metal was cosputtered, whereas the single SnO film showed regular band conduction behavior. The residual stress effect could interpret such property variation originated from the sputtering power and postoxidation-induced volumetric effects. This report makes a critical contribution to the in-depth understanding of the composition-structure-property relationship of this technically important thin film material.

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