1.
Org Lett
; 25(1): 31-36, 2023 01 13.
Artículo
en Inglés
| MEDLINE
| ID: mdl-36562600
RESUMEN
The diverse structures and profound biological activities of lignan natural products have enticed significant effort in the exploration of new methodologies for their total synthesis. We have prepared γ-butyrolactone oximes from readily available δ-nitro alcohols via Boc2O mediated cyclization. The mild conditions are compatible with a wide range of functional groups, and this methodology has been applied to the total synthesis of five lignan natural products.