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1.
J Nutr ; 150(12): 3161-3170, 2020 12 10.
Article En | MEDLINE | ID: mdl-33300039

BACKGROUND: High nut consumption has been previously associated with decreased prevalence of metabolic syndrome (MetS) regardless of race and dietary patterns. OBJECTIVES: The aim of this study was to assess whether changes in nut consumption over a 1-y follow-up are associated with changes in features of MetS in a middle-aged and older Spanish population at high cardiovascular disease risk. METHODS: This prospective 1-y follow-up cohort study, conducted in the framework of the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial, included 5800 men and women (55-75 y old) with overweight/obesity [BMI (in kg/m2) ≥27 and <40] and MetS. Nut consumption (almonds, pistachios, walnuts, and other nuts) was assessed using data from a validated FFQ. The primary outcome was the change from baseline to 1 y in features of MetS [waist circumference (WC), glycemia, HDL cholesterol, triglyceride (TG), and systolic and diastolic blood pressure] and excess weight (body weight and BMI) according to tertiles of change in nut consumption. Secondary outcomes included changes in dietary and lifestyle characteristics. A generalized linear model was used to compare 1-y changes in features of MetS, weight, dietary intakes, and lifestyle characteristics across tertiles of change in nut consumption. RESULTS: As nut consumption increased, between each tertile there was a significant decrease in WC, TG, systolic blood pressure, weight, and BMI (P < 0.05), and a significant increase in HDL cholesterol (only in women, P = 0.044). The interaction effect between time and group was significant for total energy intake (P < 0.001), adherence to the Mediterranean diet (MedDiet) (P < 0.001), and nut consumption (P < 0.001). Across tertiles of increasing nut consumption there was a significant increase in extra virgin olive oil intake and adherence to the MedDiet; change in energy intake, on the other hand, was inversely related to consumption of nuts. CONCLUSIONS: Features of MetS and excess weight were inversely associated with nut consumption after a 1-y follow-up in the PREDIMED-Plus study cohort. This trial was registered at isrctn.com as ISRCTN89898870.


Diet , Metabolic Syndrome/diet therapy , Nuts , Overweight/diet therapy , Aged , Cohort Studies , Female , Follow-Up Studies , Humans , Male , Middle Aged , Risk Factors
2.
Nutrients ; 12(7)2020 Jul 16.
Article En | MEDLINE | ID: mdl-32708828

BACKGROUND: Body weight dissatisfaction is a hindrance to following a healthy lifestyle and it has been associated with weight concerns. OBJECTIVES: The aim of this study was to assess the association between the adherence to the Mediterranean lifestyle (diet and exercise) and the desired body weight loss in an adult Mediterranean population with overweight. METHODS: Cross-sectional analysis in 6355 participants (3268 men; 3087 women) with metabolic syndrome and BMI (Body mass index) between 27.0 and 40.0 kg/m2 (55-75 years old) from the PREDIMED-Plus trial. Desired weight loss was the percentage of weight that participants wished to lose. It was categorized into four cut-offs of this percentage (Q1: <10%, n = 1495; Q2: 10-15%, n = 1804; Q3: <15-20%, n = 1470; Q4: ≥20%, n = 1589). Diet was assessed using a validated food frequency questionnaire and a 17-item Mediterranean diet questionnaire. Physical activity was assessed by the validated Minnesota-REGICOR and the validated Spanish version of the Nurses' Health Study questionnaire. RESULTS: Participants reporting higher percentages of desired weight loss (Q3 and Q4) were younger, had higher real and perceived BMI and were more likely to have abdominal obesity. Desired weight loss correlated inversely to physical activity (Q1: 2106 MET min/week; Q4: 1585 MET min/week. p < 0.001) and adherence to Mediterranean diet (Q1: 8.7; Q4: 8.3. p < 0.001). CONCLUSIONS: In older Mediterranean individuals with weight excess, desired weight loss was inversely associated with Mediterranean lifestyle adherence. Deeply rooted aspects of the MedDiet remained similar across groups. Longitudinal research is advised to be able to establish causality.


Diet, Mediterranean , Feeding Behavior/physiology , Feeding Behavior/psychology , Healthy Lifestyle , Overweight/diet therapy , Overweight/psychology , Patient Compliance , Weight Reduction Programs/methods , Age Factors , Aged , Antineoplastic Combined Chemotherapy Protocols , Body Mass Index , Cisplatin , Doxorubicin , Exercise/physiology , Female , Humans , Ideal Body Weight , Ifosfamide , Male , Methotrexate , Middle Aged , Surveys and Questionnaires
3.
Nutrients ; 12(3)2020 Mar 04.
Article En | MEDLINE | ID: mdl-32143308

Dietary polyphenol intake is associated with improvement of metabolic disturbances. The aims of the present study are to describe dietary polyphenol intake in a population with metabolic syndrome (MetS) and to examine the association between polyphenol intake and the components of MetS. This cross-sectional analysis involved 6633 men and women included in the PREDIMED (PREvención con DIeta MEDiterranea-Plus) study. The polyphenol content of foods was estimated from the Phenol-Explorer 3.6 database. The mean of total polyphenol intake was 846 ± 318 mg/day. Except for stilbenes, women had higher polyphenol intake than men. Total polyphenol intake was higher in older participants (>70 years of age) compared to their younger counterparts. Participants with body mass index (BMI) >35 kg/m2 reported lower total polyphenol, flavonoid, and stilbene intake than those with lower BMI. Total polyphenol intake was not associated with a better profile concerning MetS components, except for high-density lipoprotein cholesterol (HDL-c), although stilbenes, lignans, and other polyphenols showed an inverse association with blood pressure, fasting plasma glucose, and triglycerides. A direct association with HDL-c was found for all subclasses except lignans and phenolic acids. To conclude, in participants with MetS, higher intake of several polyphenol subclasses was associated with a better profile of MetS components, especially HDL-c.


Biomarkers , Cholesterol, HDL/blood , Dietary Supplements , Metabolic Syndrome/epidemiology , Metabolic Syndrome/metabolism , Polyphenols/administration & dosage , Aged , Body Mass Index , Cross-Sectional Studies , Diet, Mediterranean , Female , Humans , Male , Metabolic Syndrome/blood , Middle Aged , Patient Outcome Assessment , Public Health Surveillance
4.
Obesity (Silver Spring) ; 28(3): 537-543, 2020 03.
Article En | MEDLINE | ID: mdl-32090511

OBJECTIVE: The hypertriglyceridemic waist (HTGW) phenotype is characterized by abdominal obesity and high levels of triglycerides. In a cross-sectional assessment of PREDIMED-Plus trial participants at baseline, HTGW phenotype prevalence was evaluated, associated risk factors were analyzed, and the lifestyle of individuals with metabolic syndrome and HTGW was examined. METHODS: A total of 6,874 individuals aged 55 to 75 with BMI ≥ 27 and < 40 kg/m2 were included and classified by presence (HTGW+ ) or absence (HTGW- ) of HTGW (waist circumference: men ≥ 102 cm, women ≥ 88 cm; fasting plasma triglycerides ≥ 150 mg/dL). Analytical parameters and lifestyle (energy intake and expenditure) were analyzed. RESULTS: A total of 38.2% of the sample met HTGW+ criteria. HTGW+ individuals tended to be younger, have a greater degree of obesity, be sedentary, and be tobacco users. They had higher peripheral glucose, total cholesterol, and low-density lipoprotein cholesterol levels; had lower high-density lipoprotein cholesterol levels; and had increased prevalence of type 2 diabetes mellitus. Mediterranean diet (MedDiet) adherence and physical activity were greater in HTGW- patients. Age, BMI, tobacco use, total energy expenditure, hypertension, type 2 diabetes mellitus, and MedDiet adherence were associated with HTGW+ . CONCLUSIONS: HTGW is a highly prevalent phenotype in this population associated with younger age, higher BMI, tobacco use, and decreased MedDiet adherence. HTGW- individuals were more physically active with greater total physical activity, and fewer had hypertension.


Hypertriglyceridemic Waist/epidemiology , Life Style , Obesity, Abdominal/complications , Triglycerides/blood , Waist Circumference/physiology , Aged , Cross-Sectional Studies , Female , Humans , Male , Middle Aged , Phenotype , Risk Factors
5.
Antioxidants (Basel) ; 8(11)2019 Nov 08.
Article En | MEDLINE | ID: mdl-31717390

Overweight and obesity are important risk factors for type 2 diabetes (T2D). Moving towards healthier diets, namely, diets rich in bioactive compounds, could decrease the odds of suffering T2D. However, those individuals with high body mass index (BMI) may have altered absorption or metabolism of some nutrients and dietary components, including polyphenols. Therefore, we aimed to assess whether high intakes of some classes of polyphenols are associated with T2D in a population with metabolic syndrome and how these associations depend on BMI and sex. This baseline cross-sectional analysis includes 6633 participants from the PREDIMED-Plus trial. Polyphenol intakes were calculated from food frequency questionnaires (FFQ). Cox regression models with constant time at risk and robust variance estimators were used to estimate the prevalence ratios (PRs) for polyphenol intake and T2D prevalence using the lowest quartile as the reference group. Analyses were stratified by sex and BMI groups (overweight and obese) to evaluate potential effect modification. Catechins, proanthocyanidins, hydroxybenzoic acids, and lignans were inversely associated with T2D. Hydroxycinnamic acids were directly related in men. These associations were different depending on sex and BMI, that is, women and overweight obtained stronger inverse associations.

6.
Nutr Metab Cardiovasc Dis ; 29(9): 887-905, 2019 09.
Article En | MEDLINE | ID: mdl-31377181

BACKGROUND AND AIMS: The metabolic syndrome (MetS) is a cluster of coexisting cardiovascular risk factors. The role of specific dietary fats was reemphasized by dietary recommendations. This systematic review aims to assess evidence for the effect of dietary fat intake on MetS occurrence and reversion in adults. METHODS AND RESULTS: The MEDLINE database was used to search the existing literature. We included observational studies that analyzed dietary fat intake in adults with MetS and clinical trials that compared the effects of different dietary fat diets on MetS and/or its components. Thirty articles were selected (14 observational and 16 clinical trials), and we included information of dietary fat and fatty acids as well as MetS, body mass index, cholesterol, hypertension, and diabetes in adults. SFA intake was found to be positively associated with MetS components. Most of the observational reviewed studies found beneficial associations between MUFA and PUFA (including n-3 and n-6 subtypes) intake and MetS components. Clinical trials also supported the benefits of MUFA- or PUFA-enriched diets (including low-fat diets) in reducing MetS. CONCLUSIONS: The effects of dietary SFAs on MetS will be influenced by other specific nutrients. Replacement of SFA by MUFA and PUFA has been associated with a decrease in MetS. Dietary recommendations should emphasize on different qualities of fat intake, not only to reduce total fat intake, to obtain health benefits in adults.


Dietary Fats/administration & dosage , Fatty Acids, Monounsaturated/administration & dosage , Fatty Acids, Omega-3/administration & dosage , Fatty Acids, Omega-6/administration & dosage , Metabolic Syndrome/prevention & control , Adolescent , Adult , Aged , Aged, 80 and over , Dietary Fats/adverse effects , Fatty Acids, Monounsaturated/adverse effects , Fatty Acids, Omega-3/adverse effects , Fatty Acids, Omega-6/adverse effects , Female , Humans , Male , Metabolic Syndrome/diagnosis , Metabolic Syndrome/epidemiology , Middle Aged , Nutritive Value , Prevalence , Protective Factors , Recommended Dietary Allowances , Risk Assessment , Risk Factors , Young Adult
7.
Nutrients ; 11(8)2019 Aug 14.
Article En | MEDLINE | ID: mdl-31416272

BACKGROUND: Metabolic Syndrome (MetS) is associated with higher rates of cardiovascular disease (CVD), type 2 diabetes mellitus, and cancer worldwide. OBJECTIVE: To assess fat intake in older adults with or without MetS. DESIGN: Cross-sectional nutritional survey in older adults living in the Balearic Islands (n = 477, 48% women, 55-80 years old) with no previous CVD. METHODS: Assessment of fat (total fat, MUFA, PUFA, SFA, TFA, linoleic acid, α-linolenic acid, marine and non-marine ω-3 FA, animal fat and vegetable fat, cholesterol) and macronutrient intake using a validated food frequency questionnaire, and its comparison with recommendations of the US Institute of Medicine (IOM) and the Spanish Society of Community Nutrition (SENC). RESULTS: Participants with MetS showed higher BMI, lower physical activity, higher total fat and MUFA intake, and lower intake of energy, carbohydrates, and fiber than participants without MetS. Men and women with MetS were below the Acceptable Macronutrient Distribution Range (AMDR) proposed by IOM for carbohydrates and above the AMDR for total fat and MUFAs, and women were below the AMDR proposed for α-linolenic acid (ALA) compared with participants without MetS. CONCLUSIONS: Subjects with MetS were less likely to meet IOM and SENC recommendations for fat and macronutrient intakes as compared to non-MetS subjects.


Dietary Fats/administration & dosage , Metabolic Syndrome/epidemiology , Age Factors , Aged , Aged, 80 and over , Cross-Sectional Studies , Diet Surveys , Diet, Healthy , Dietary Fats/adverse effects , Female , Humans , Male , Metabolic Syndrome/diagnosis , Metabolic Syndrome/prevention & control , Middle Aged , Nutritional Status , Nutritive Value , Protective Factors , Recommended Dietary Allowances , Risk Factors , Risk Reduction Behavior , Spain/epidemiology
8.
Nutrients ; 11(7)2019 06 29.
Article En | MEDLINE | ID: mdl-31261967

Background: The effect of dietary fat intake on the metabolic syndrome (MetS) and in turn on cardiovascular disease (CVD) remains unclear in individuals at high CVD risk. Objective: To assess the association between fat intake and MetS components in an adult Mediterranean population at high CVD risk. Design: Baseline assessment of nutritional adequacy in participants (n = 6560, men and women, 55-75 years old, with overweight/obesity and MetS) in the PREvención con DIeta MEDiterránea (PREDIMED)-Plus randomized trial. Methods: Assessment of fat intake (total fat, monounsatured fatty acids: MUFA, polyunsaturated fatty acids: PUFA, saturated fatty acids: SFA, trans-fatty acids: trans-FA, linoleic acid, α-linolenic acid, and ω-3 FA) using a validated food frequency questionnaire, and diet quality using 17-item Mediterranean dietary questionnaire and fat quality index (FQI). Results: Participants in the highest quintile of total dietary fat intake showed lower intake of energy, carbohydrates, protein and fiber, but higher intake of PUFA, MUFA, SFA, TFA, LA, ALA and ω-3 FA. Differences in MetS components were found according to fat intake. Odds (5th vs. 1st quintile): hyperglycemia: 1.3-1.6 times higher for total fat, MUFA, SFA and ω-3 FA intake; low high-density lipoprotein cholesterol (HDL-c): 1.2 higher for LA; hypertriglyceridemia: 0.7 lower for SFA and ω-3 FA intake. Conclusions: Dietary fats played different role on MetS components of high CVD risk patients. Dietary fat intake was associated with higher risk of hyperglycemia.


Cardiovascular Diseases/epidemiology , Dietary Fats/adverse effects , Dyslipidemias/epidemiology , Hyperglycemia/epidemiology , Metabolic Syndrome/epidemiology , Aged , Biomarkers/blood , Blood Glucose/analysis , Cardiovascular Diseases/diagnosis , Cardiovascular Diseases/prevention & control , Cross-Sectional Studies , Diet, Mediterranean , Dietary Fats/administration & dosage , Dyslipidemias/blood , Dyslipidemias/diagnosis , Dyslipidemias/diet therapy , Female , Humans , Hyperglycemia/blood , Hyperglycemia/diagnosis , Hyperglycemia/diet therapy , Lipids/blood , Male , Metabolic Syndrome/blood , Metabolic Syndrome/diagnosis , Metabolic Syndrome/diet therapy , Middle Aged , Risk Assessment , Risk Factors , Spain/epidemiology , Treatment Outcome
9.
Nutrients ; 11(4)2019 Mar 30.
Article En | MEDLINE | ID: mdl-30935087

BACKGROUND: Nut consumption has been associated with improved nutrient adequacy and diet quality in healthy adult populations but this association has never been explored in individuals at high cardiovascular risk. OBJECTIVE: to assess the associations between consumption of nuts and nutrient adequacy and diet quality in a Mediterranean population at high cardiovascular risk. DESIGN: baseline assessment of nutritional adequacy in participants (n = 6060, men and women, with ages 55⁻75 years old, with overweight/obesity and metabolic syndrome) in the PREDIMED-PLUS primary cardiovascular prevention randomized trial. METHODS: nut intake was assessed using a validated food frequency questionnaire. Participants who reported consuming zero quantity of nuts were classified as 'non-nut consumers'. 'Nut consumers' were participants who reported consuming any quantity of nuts. Nineteen micronutrients were examined (vitamins B1, B2, B3, B6, B12, A, C, D, E and folic acid; Ca, K, P, Mg, Fe, Se, Cr, Zn, and iodine). The proportion of micronutrient inadequacy was estimated using the estimated average requirements (EAR) or adequate intake (AI) cut-points. Diet quality was also assessed using a 17-item Mediterranean dietary questionnaire (Mediterranean diet score, MDS), a carbohydrate quality index (CQI) and a fat quality index (FQI). RESULTS: eighty-two percent of participants were nut consumers (median of nut consumption 12.6 g/day; interquartile range: 6.0⁻25.2). Nut consumers were less likely to be below the EAR for vitamins A, B1, B2, B6, C, D, E, folic acid, and Ca, Mg, Se and Zn than non-nut consumers. Nut consumers were also more likely to be above the AI for K and Cr than non-nut consumers. Nut consumers had lower prevalence of inadequate micronutrient intakes, but also higher CQI, higher FQI, and better scores of adherence to the Mediterranean diet (Mediterranean diet score, MDS). CONCLUSIONS: nut consumers had better nutrient adequacy, diet quality, and adherence to the MedDiet than those non-nut consumers.


Cardiovascular Diseases/prevention & control , Diet/adverse effects , Metabolic Syndrome/complications , Nuts , Obesity/complications , Aged , Cardiovascular Diseases/etiology , Diet/methods , Diet, Mediterranean , Energy Intake , Female , Humans , Male , Micronutrients/analysis , Middle Aged , Nutrition Surveys , Nutritional Status , Risk Factors
10.
PLoS One ; 13(10): e0206307, 2018.
Article En | MEDLINE | ID: mdl-30356331

Biomarkers have been postulated as essential variables to measure the effects of exercise on the human body. To investigate the relationship between physical fitness (PF) and blood biomarkers that are associated with disease risk in Spanish older adults, four hundred and twenty-nine adults (57% females) aged older than 55 years from a cross-sectional study were included. A battery of PF test was performed, and participants were divided into 3 groups: low, medium and high fitness. Blood samples were collected, and subjects were also grouped based on a particular biomarker being within its reference range. Furthermore, drug intake and dietary intake were considered for each participant. Higher concentrations out of the reference range were observed for vitamin 25(OH)D (67.9%) and total cholesterol (TC) (58.6%). Participants from the low PF group presented lower significant concentrations out of the reference range for vitamin B12 and triglycerides; however, participants in the low PF group showed higher significant concentrations out of the reference range for total homocysteine, creatinine, TC, HDL-cholesterol and LDL-cholesterol (LDL-c) than those in the high PF group (all p<0.05). Considering drugs related to blood lipid modifications, subjects who regularly consumed lipid reducers presented higher significant concentrations out of the reference range for TC and LDL-c than participants who did not take these drugs (p<0.01). Participants from the high PF group presented better blood marker profiles, namely, lower blood markers related to disease risk out of the reference range. These blood markers could be used as a routine method for considering PF groups in older adults.


Body Constitution , Physical Fitness/physiology , Aged , Aged, 80 and over , Biomarkers/blood , Body Mass Index , Cholesterol, HDL/blood , Cholesterol, LDL/blood , Cross-Sectional Studies , Exercise , Exercise Test , Female , Humans , Lipids/blood , Male , Middle Aged , Spain , Triglycerides/blood , Vitamin B 12/blood , Vitamin D/blood , Waist Circumference
11.
Nutr Hosp ; 35(3): 612-619, 2018 May 10.
Article En | MEDLINE | ID: mdl-29974770

BACKGROUND: fluid intake before, during and after exercise is the most important way to replace water lost during exercise and avoid dehydration. AIM: to assess fluid intake habits before, during and after exercise in amateur basketball players on both training and competition days. METHODS: one hundred and eighty-three amateur basketball players (87 women and 96 men, 19-29 years old) were interviewed. Data was obtained from a drinking habits questionnaire. RESULTS: overall, 20.8%, 5.5% and 2.7% of subjects did not drink before, during and after exercise on training days, respectively; 17.5% of subjects did not drink before exercise on competition days. Water was the preferred beverage before, during and after exercise on both training and competition days, with fruit juice being the second most consumed beverage before exercise. All subjects also drank fizzy drinks and other beverages during exercise on competition days. According to the recommendations, good hydration habits were found in 54.6%, 74.2% and 76.5% of subjects before, during and after training days, respectively. CONCLUSIONS: most amateur basketball players drink before, during and after exercise on both training and competition days, but not all of them complied with the hydration recommendations.


Basketball/physiology , Drinking , Adult , Athletes , Cross-Sectional Studies , Dehydration/prevention & control , Female , Habits , Humans , Male , Physical Education and Training , Surveys and Questionnaires , Young Adult
12.
Nutr. hosp ; 35(3): 612-619, mayo-jun. 2018. tab, graf
Article En | IBECS | ID: ibc-180118

Background: fluid intake before, during and after exercise is the most important way to replace water lost during exercise and avoid dehydration. Aim: to assess fluid intake habits before, during and after exercise in amateur basketball players on both training and competition days. Methods: one hundred and eighty-three amateur basketball players (87 women and 96 men, 19-29 years old) were interviewed. Data was obtained from a drinking habits questionnaire. Results: overall, 20.8%, 5.5% and 2.7% of subjects did not drink before, during and after exercise on training days, respectively; 17.5% of subjects did not drink before exercise on competition days. Water was the preferred beverage before, during and after exercise on both training and competition days, with fruit juice being the second most consumed beverage before exercise. All subjects also drank fizzy drinks and other beverages during exercise on competition days. According to the recommendations, good hydration habits were found in 54.6%, 74.2% and 76.5% of subjects before, during and after training days, respectively. Conclusions: most amateur basketball players drink before, during and after exercise on both training and competition days, but not all of them complied with the hydration recommendations


Introducción: la ingesta de líquidos antes, durante y tras el ejercicio es la forma más importante de recuperar el agua perdida durante el ejercicio y de evitar la deshidratación. Objetivo: analizar los hábitos de ingesta de líquidos, durante y tras el ejercicio en jugadores de baloncesto amateurs tanto durante el entrenamiento como durante la competición. Métodos: fueron entrevistados 183 jugadores de baloncesto amateurs (87 mujeres y 96 hombres, de 19-29 años de edad). Los datos se obtuvieron por aplicación de un cuestionario de hábitos de bebida. Resultados: globalmente, el 20,8%, 5,5% y 2,7% de los sujetos no bebieron antes, durante y tras el entrenamiento, respectivamente; el 17,5% de los sujetos no bebieron antes de la competición. El agua fue la bebida preferida antes, durante y tras el ejercicio, tanto durante el entrenamiento como durante la competición, en tanto que los zumos de frutas fueron la segunda bebida consumida antes del ejercicio. Todos los sujetos tomaron bebidas gaseosas y de otro tipo durante la competición. De acuerdo con las recomendaciones, se encontraron buenos hábitos de hidratación en el 54,6%, 74,2% y 76,5% de los sujetos antes, durante y tras el entrenamiento, respectivamente. Conclusiones: la mayoría de los jugadores de baloncesto amateurs beben antes, durante y tras el ejercicio, tanto durante el entrenamiento como durante la competición, pero no todos ellos cumplen con las recomendaciones de hidratación


Humans , Male , Female , Young Adult , Adult , Basketball/physiology , Drinking , Athletes , Cross-Sectional Studies , Dehydration/prevention & control , Habits , Physical Education and Training , Surveys and Questionnaires
13.
Nutrients ; 10(1)2018 Jan 10.
Article En | MEDLINE | ID: mdl-29320413

The aim was to assess inflammatory markers among adults and adolescents in relation to the adherence to the Mediterranean diet. A random sample (219 males and 379 females) of the Balearic Islands population (12-65 years) was anthropometrically measured and provided a blood sample to determine biomarkers of inflammation. Dietary habits were assessed and the adherence to the Mediterranean dietary pattern calculated. The prevalence of metabolic syndrome increased with age in both sexes. The adherence to the Mediterranean diet in adolescent males was 51.3% and 45.7% in adults, whereas in females 53.1% and 44.3%, respectively. In males, higher adherence to the Mediterranean diet was associated with higher levels of adiponectin and lower levels of leptin, tumor necrosis factor alpha (TNF-α), plasminogen activator inhibitor 1 (PAI-1) and high-sensitivity C-reactive protein (hs-CRP) in adults, but not in young subjects. In females, higher adherence was associated with lower levels of leptin in the young group, PAI-1 in adults and hs-CRP in both groups. With increasing age in both sexes, metabolic syndrome increases, but the adherence to the Mediterranean diet decreases. Low adherence to the Mediterranean dietary pattern (MDP) is directly associated with a worse profile of plasmatic inflammation markers.


Diet, Mediterranean , Feeding Behavior , Health Behavior , Inflammation Mediators/blood , Metabolic Syndrome/prevention & control , Adolescent , Adolescent Behavior , Adult , Age Factors , Aged , Biomarkers/blood , Child , Cross-Sectional Studies , Diet Surveys , Female , Health Knowledge, Attitudes, Practice , Humans , Male , Metabolic Syndrome/blood , Metabolic Syndrome/diagnosis , Metabolic Syndrome/epidemiology , Middle Aged , Prevalence , Protective Factors , Risk Factors , Sex Factors , Spain/epidemiology , Time Factors , Young Adult
14.
PLoS One ; 12(10): e0185318, 2017.
Article En | MEDLINE | ID: mdl-28985222

The aim was to assess the trace element contents in toenails of older adults and its association with regular physical activity. Cross-sectional multicentre study in Spain, collecting data from a random sample of 380 participants (54% female) aged 55-80 years (men) and 60-80 years (women) with no previously documented cardiovascular disease. Physical activity performed was measured using the Minnesota Leisure-time Physical Activity Questionnaire. The 25 most inactive and 25 most active individuals for each sex were selected for this study (final sample n = 100). Anthropometric measurements were performed and toenail samples collected for calcium (Ca), chromium (Cr), iron (Fe), cobalt (Co), nickel (Ni), zinc (Zn), selenium (Se) and mercury (Hg) analysis. Significant differences between sexes were reported in Ca concentrations, women having lower concentrations than men. No differences were reported in trace element contents between active and inactive men. Active women showed higher Ca, Cr, Fe, Co, and Zn and lower Hg contents than their inactive peers (all p<0.05). Inactive women showed lower Ca and Co levels (735.0 mg/kg and 4.5 µg/kg, respectively) than inactive men (1170.0 mg/kg and 7.9 µg/kg, respectively). Active women had lower Ca and higher levels of Cr (936.0 mg/kg and 1230.0 µg/kg, respectively) than active men (1070.0 mg/kg and 522.0 µg/kg, respectively). The present data added new information on the element contents in toenails of healthy Spanish older adults. The concentration of trace elements was similar in both sexes except for Ca which were lower in women. The trace element contents in women's toenails, but not in men, were markedly influenced by physical activity, with higher levels of Ca and Fe and lower Hg among active females.


Exercise/physiology , Nails/chemistry , Trace Elements/analysis , Aged , Aged, 80 and over , Calcium/analysis , Chromium/analysis , Cobalt/analysis , Cross-Sectional Studies , Female , Humans , Iron/analysis , Male , Mercury/analysis , Middle Aged , Nickel/analysis , Selenium/analysis , Sex Factors , Spain , Zinc/analysis
15.
Nutrients ; 9(7)2017 Jul 14.
Article En | MEDLINE | ID: mdl-28708083

The aim of this work was to assess ten-year trends (1999-2010) of adherence to the Mediterranean dietary pattern (MDP) among the Balearic Islands' adult population. Two independent cross-sectional dietary surveys (1999-2000, n = 1200 and 2009-2010 n = 1388, including participants aged 16-65 years) were carried out in the Balearic Islands, Spain. Dietary habits were assessed by means of two 24 h diet recalls and a validated semi-quantitative food-frequency questionnaire that covers 145 food items. Adherence to the MDP was defined according to a score constructed considering the consumption of nine MDP characteristic components: high monounsaturated fatty acids:saturated fatty acids (MUFA:SFA) ratio, moderate ethanol consumption, high legumes, cereals and roots, fruits, vegetables, and fish consumption, and low consumption of meat and milk. Socio-economic status, education level, lifestyle factors and health status were also assessed. Adherence to the MDP was 43.1% (SD 5.8) in 1999-2000 and 44.6% (SD 8.3) in 2009-2010. Higher age was directly associated with higher adherence to the MDP, and this association was stronger in males than in females. Young generations and smokers showed the lowest adherence to MDP, whereas people with higher educational and socio-economic level, and who were physically active showed the highest adherence. According to the place of birth, the increase in the percentage of the adherence to the MDP was observed to be smaller among the Balearic Island's natives than among people born abroad. In 2009-2010, individuals in the MDP's fourth quartile were more likely to be older (aged 46-65 years), and were less likely to have a low occupational level, to have a light physical activity level and to be smoker than in 1999-2000. The adherence to the MDP has been stabilized and slightly recovered among the Balearic Islands' adult population in the last decade.


Diet, Mediterranean/statistics & numerical data , Diet/trends , Patient Compliance/statistics & numerical data , Adult , Age Factors , Aged , Cross-Sectional Studies , Exercise , Female , Humans , Inflammation , Life Style , Male , Mental Recall , Middle Aged , Nutrition Surveys , Obesity/epidemiology , Oxidative Stress , Sex Factors , Smoking/epidemiology , Socioeconomic Factors , Spain/epidemiology , Surveys and Questionnaires
16.
Nutrients ; 9(7)2017 Jul 06.
Article En | MEDLINE | ID: mdl-28684703

Objectives: To assess prevailing food patterns, and its association with physical activity and fitness among Spanish older adults. Methods: Cross-sectional study in Spain, collecting data from a sample (n = 380; 54% female) aged 55-80 years (men) and 60-80 years (women) with no previously documented cardiovascular disease. Body weight, body fat and waist circumference were assessed. Physical activity performed was measured using the Minnesota Leisure-time Physical Activity Questionnaire (LTPA). Physical fitness was assessed using a validated physical fitness test battery. Food consumption was assessed by a validated semi-quantitative food-frequency questionnaire. Factor analysis identified two major dietary food patterns: "Western" (WDP) and "Mediterranean" (MDP) dietary patterns. Results: Participants in MDP's fourth quartile were classified in the second (men) and third (men and women) tertile of LTPA. After adjusting for age, body fat, waist-to-height ratio, and METs, in both sexes, a negative significant association was found between 30-s Chair stand and 6-min walking test, a positive significant association was found between 30-m Gait speed and 8-foot Time Up-and-Go (except in men) tests with WDP. The 30-m Gait speed test was negatively associated with MDP in men. Conclusions: MDP is associated with more time spent on LTPA, and this association was independent of body composition and a fast gait speed in men. WDP is associated with slower gait speed and lower body strength, agility and aerobic endurance. MDP has protective effect on healthy physical fitness, and WDP may be a contributor to frailty.


Diet, Mediterranean , Diet, Western , Exercise , Physical Fitness , Aged , Aged, 80 and over , Body Composition , Cross-Sectional Studies , Diet Records , Feeding Behavior , Female , Humans , Male , Middle Aged
17.
Nutr Hosp ; 33(Suppl 3): 309, 2016 Jul 13.
Article En | MEDLINE | ID: mdl-27491574

INTRODUCTION: Data on hydration status in older adults are scarce and there are very few studies focusing on the impact of physical activity (PA) on drinking behavior. OBJECTIVE: To assess the impact of physical activity and sedentarism on fluid intake in Spanish elderly. METHODS: 433 non-institutionalized Spanish older adults (58% females), aged 55-88 years, volunteered for the PHYSMED study. PA data were obtained by means of the Minnesota and EXERNET questionnaires. Population was divided into four groups: ILS (inactive and low sedentary), IHS (inactive and high sedentary), ALS (active and low sedentary) and AHS (active and high sedentary). Serum from fasting blood samples was analysed for osmolarity. RESULTS: The mean of total liquid intake was 1,751 ± 628 mL/d. Significant differences were observed for total liquid intake between ILS/ALS and IHS/ALS (p < 0.001). ALS subjects consumed a higher amount of beverages such as water, juice, milk, coffee, sport drink, beer, wine and distilled drinks than the other PA groups. There was a significant difference for water intake between PA groups (p < 0.01). Serum osmolarity values were within references ranges in all subjects, and there was a signifi cant difference between PA groups (p < 0.01). CONCLUSIONS: Spanish older adults meet the DACH recommendations set by the German, Austrian and Swiss nutrition societies' liquid intake recommendations in the mean independently of PA and sedentary level. All participants are within reference ranges of serum osmolarity. Subjects in the active and low sedentary group consumed higher amounts of water and other beverages than in the other PA groups.


Body Water/physiology , Drinking , Exercise/physiology , Sedentary Behavior , Aged , Aged, 80 and over , Cross-Sectional Studies , Drinking Behavior , Humans , Middle Aged , Nutrition Surveys , Spain , Surveys and Questionnaires
18.
Nutr. hosp ; 33(supl.3): 4-8, 2016. tab, graf
Article En | IBECS | ID: ibc-154655

Introduction: Data on hydration status in older adults are scarce and there are very few studies focusing on the impact of physical activity (PA) on drinking behavior. Objective: To assess the impact of physical activity and sedentarism on fluid intake in Spanish elderly. Methods: 433 non-institutionalized Spanish older adults (58% females), aged 55-88 years, volunteered for the PHYSMED study. PA data were obtained by means of the Minnesota and EXERNET questionnaires. Population was divided into four groups: ILS (inactive and low sedentary), IHS (inactive and high sedentary), ALS (active and low sedentary) and AHS (active and high sedentary). Serum from fasting blood samples was analysed for osmolarity. Results: The mean of total liquid intake was 1,751 ± 628 mL/d. Significant differences were observed for total liquid intake between ILS/ALS and IHS/ALS (p < 0.001). ALS subjects consumed a higher amount of beverages such as water, juice, milk, coffee, sport drink, beer, wine and distilled drinks than the other PA groups. There was a significant difference for water intake between PA groups (p < 0.01). Conclusions: Spanish older adults meet the DACH recommendations set by the German, Austrian and Swiss nutrition societies’ liquid intake recommendations in the mean independently of PA and sedentary level. All participants are within reference ranges of serum osmolarity. Subjects in the active and low sedentary group consumed higher amounts of water and other beverages than in the other PA groups (AU)


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Humans , Male , Female , Aged , Motor Activity/physiology , Drinking , Water-Electrolyte Balance/physiology , Dehydration/epidemiology , Health of Institutionalized Elderly , Sedentary Behavior
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