RESUMEN
PURPOSE: Breast cancer patients are more likely to gain than lose weight during chemotherapy. Weight gain due to chemotherapy in breast cancer patients increases the likelihood of complications and the risk of recurrence. The study aimed to investigate changes in weight, body composition, and physical activity in breast cancer patients receiving adjuvant chemotherapy. METHOD: This was a prospective longitudinal study. The participants of this study were 37 patients who underwent adjuvant chemotherapy between August 2016 and March 2017â¯at a University hospital, Seoul, South Korea. We measured weight and body composition using a bioelectrical impedance method, and physical activity through a questionnaire, three times during the study period. The collected data were analyzed using descriptive statistics and repeated measures analysis. RESULTS: There were no changes in weight, body mass index (BMI), body composition, and physical activity during adjuvant chemotherapy. There were no statistically significant differences in weight and BMI according to clinical characteristics. However, there were significant differences in total body water, muscle mass, and body fat percentage according to menopause status. The changes in physical activity showed no differences according to clinical characteristics. CONCLUSIONS: There was no significant change in weight, body composition, and physical activity during adjuvant chemotherapy in participants with breast cancer. However, total body water, muscle mass, and body fat percentage differed according to menopause status, and body fat percentage appeared to increase rapidly in premenopausal participants following adjuvant chemotherapy. We should pay close attention to the weight of premenopausal women receiving adjuvant chemotherapy.