[Effects of allopurinol on uric acid metabolism and lipid peroxidation in ischemic heart disease patients with stable angina]. / Vliianie allopurinola na obmen mochevoi kisloty i perekisnoe okislenie lipidov u bol'nykh ishemicheskoi bolezn'iu serdtsa so stabil'noi stenokardiei.

The study was undertaken to examine 20 healthy individuals and 60 IHD patients with stable angina of various functional classes. All the examinees were males. By the random sampling method, all the patients were divided into 2 groups: (1) 30 were on erinit and (2) 30 on erinit and allopurinol in conventional therapeutical doses. The level of uric acid in the serum and daily urine, lipid peroxidation, the antioxidative system and central hemodynamics were examined in all the examinees. The examination was performed on admission and every 10-14 days of their hospital stay. A combined therapy with erinit and allopurinol led to a significant decrease in serum and daily urinary levels of uric acid and lipid peroxidation antioxidative system and an improvement of central hemodynamics. It is concluded that it is useful to include allopurinol into the combined therapy for IHD patients with stable angina.

[Various clinical and instrumental parallels in the condition of the lungs and heart in patients with rheumatoid arthritis]. / Nekotorye kliniko-instrumental'nye paralleli sostoianiia legkikh i serdtsa u bol'nykh revmatoidnym artritom.

Comparative clinical and instrumental examination of 33 patients with seronegative and 67 patients with seropositive rheumatoid arthritis (RA) has revealed that patients with seropositive RA often manifest the functional and roentgenomorphological signs of lung damage. Pulmonary lesions related pathogenetically to RA were encountered equally often in patients of both groups, whereas those caused by concomitant chronic nonspecific pulmonary diseases were more characteristic of patients with seropositive RA apparently because of a more powerful suppression of immunity. In addition, in spite of the fact that the latter patients did not make any complaints on the part of the heart, they did manifest abnormalities of the phase structure of the cardiac cycle and central hemodynamics.