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1.
Eur Ann Allergy Clin Immunol ; 51(6): 265-273, 2019 11.
Artículo en Inglés | MEDLINE | ID: mdl-31287261

RESUMEN

Summary: This study was aimed to reveal the prevalence of dog allergy and other common allergy and allergic symptoms in police dog trainers. Fifty-six police dog trainers and 150 workers as control group were included in this study. Medical records of dog trainers including respiratory, skin, eye symptoms and physical examinations and skin prick test results are compared with the medical records of control group. Positive SPT to dog was present in 21.4% of dog trainers, whereas the frequency of sensitization to dog in the control group was 1.3% (p minor 0.001). Dog allergy development risk is found 20 times greater in dog trainers than control group. In multiple logistic regression analysis, it was found that atopy was associated with dog allergy likelihood. Sensitization to dog allergens is an important occupational problem for dog trainers.


Asunto(s)
Pelaje de Animal/inmunología , Perros , Hipersensibilidad Inmediata/epidemiología , Enfermedades Profesionales/epidemiología , Adulto , Animales , Femenino , Humanos , Masculino , Enfermedades Profesionales/inmunología , Policia/estadística & datos numéricos , Pruebas Cutáneas/métodos
2.
J Laryngol Otol ; 133(6): 466-476, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-31099325

RESUMEN

OBJECTIVE: To investigate whether oxytocin can prevent ototoxicity related to acoustic trauma. METHODS: Twenty-eight rats were divided into four groups: noise (group 1), control (group 2), noise plus oxytocin (group 3), and oxytocin (group 4). Intratympanic oxytocin was administered on days 1, 2, 4, 6, 8 and 10 in groups 3 and 4. Groups 1 and 3 were exposed to acoustic trauma. Distortion product otoacoustic emission and auditory brainstem response testing were performed in all groups. RESULTS: In group 1, auditory brainstem response thresholds increased significantly after acoustic trauma. In group 3, auditory brainstem response thresholds increased significantly on day 1 after acoustic trauma, but there were no significant differences between thresholds at baseline and on the 7th and 21st days. In group 1, significant differences were observed between distortion product otoacoustic emission signal-to-noise ratios measured before and on days 1, 7 and 21 after acoustic trauma. In group 3, no significant differences were observed between the distortion product otoacoustic emission signal-to-noise ratios measured before and on days 7 and 21 after acoustic trauma. CONCLUSION: Oxytocin had a therapeutic effect on rats exposed to acoustic trauma in this experiment.


Asunto(s)
Pérdida Auditiva Provocada por Ruido/tratamiento farmacológico , Pérdida Auditiva Provocada por Ruido/patología , Oxitocina/farmacología , Membrana Timpánica/efectos de los fármacos , Animales , Biopsia con Aguja , Modelos Animales de Enfermedad , Potenciales Evocados Auditivos del Tronco Encefálico/efectos de los fármacos , Pérdida Auditiva Provocada por Ruido/diagnóstico , Inmunohistoquímica , Inyecciones Intralesiones , Masculino , Emisiones Otoacústicas Espontáneas/efectos de los fármacos , Distribución Aleatoria , Ratas , Ratas Sprague-Dawley , Valores de Referencia , Relación Señal-Ruido , Estadísticas no Paramétricas , Resultado del Tratamiento
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