RESUMEN
Commentary on: Kaundal R, Bhatia P, Jain A, et al. Randomized controlled trial of twice-daily versus alternate-day oral iron therapy in the treatment of iron-deficiency anemia. Ann Hematol. 2020;99:57-63. Series Editor: Dr Teck Khong, DTB Associate Editor, Clinical Pharmacology, St George's, University of London, UK.
Asunto(s)
Anemia Ferropénica , Hierro , Humanos , Hierro/uso terapéutico , Anemia Ferropénica/tratamiento farmacológico , Administración OralRESUMEN
Commentary on: Heerspink HJL, Stefánsson BV, Correa-Rotter R, et al Dapagliflozin in patients with chronic kidney disease. N Engl J Med 2020;383:1436-46. Series Editor: Dr Teck Khong, DTB Associate Editor, Clinical Pharmacology, St George's, University of London, UK.
Asunto(s)
Compuestos de Bencidrilo , Insuficiencia Renal Crónica , Humanos , Compuestos de Bencidrilo/uso terapéutico , Glucósidos/uso terapéutico , Insuficiencia Renal Crónica/tratamiento farmacológicoRESUMEN
Commentary on: Mackenzie IS, Rogers A, Poulter NR, et al Cardiovascular outcomes in adults with hypertension with evening vs morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial. Lancet 2022;400:1417-25.
Asunto(s)
Antihipertensivos , Hipertensión , Adulto , Humanos , Presión Sanguínea , Estudios de Tiempo y Movimiento , Estudios Prospectivos , Esquema de Medicación , Hipertensión/tratamiento farmacológico , Ensayos Clínicos Controlados Aleatorios como AsuntoRESUMEN
Commentary on: Anker SD, Butler J, Filippatos G, et al Empagliflozin in heart failure with a preserved ejection fraction. New England Journal of Medicine, 2021; 385:1451-61.
Asunto(s)
Insuficiencia Cardíaca , Humanos , Insuficiencia Cardíaca/tratamiento farmacológico , Volumen Sistólico , Compuestos de Bencidrilo/uso terapéutico , Glucósidos/uso terapéuticoRESUMEN
Commentary on: Sheppard JP, Burt J, Lown M, et al Effect of antihypertensive medication reduction vs usual care on short-term blood pressure control in patients with hypertension aged 80 years and older: The OPTIMISE randomized clinical trial. JAMA 2020;323:2039-51.Series co-ordinator: Dr Teck Khong, DTB Associate Editor, Clinical Pharmacology, St George's, University of London, UK.
Asunto(s)
Antihipertensivos , Deprescripciones , Hipertensión , Anciano de 80 o más Años , Antihipertensivos/uso terapéutico , Presión Sanguínea , Humanos , Hipertensión/tratamiento farmacológico , Ensayos Clínicos Controlados Aleatorios como AsuntoRESUMEN
Commentary on: Chow CK, Atkins ER, Hillis GS, et al Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial. Lancet 2021;398:1043-52. Series co-ordinator: Dr Teck Khong, DTB Associate Editor Clinical Pharmacology, St George's, University of London, UK.
Asunto(s)
Antihipertensivos , Hipertensión , Antihipertensivos/administración & dosificación , Ensayos Clínicos Fase III como Asunto , Quimioterapia Combinada , Humanos , Hipertensión/tratamiento farmacológico , Irbesartán/administración & dosificación , Ensayos Clínicos Controlados Aleatorios como AsuntoRESUMEN
Commentary on: Maron DJ, Hochman JS, Reynolds HR, et al Initial Invasive or Conservative Strategy for Stable Coronary Disease. N Engl J Med 2020;382:1395-1407.Series co-ordinator: Dr Teck Khong, DTB Associate Editor Clinical Pharmacology, St George's, University of London, UK.
Asunto(s)
Enfermedad de la Arteria Coronaria , Isquemia Miocárdica , Intervención Coronaria Percutánea , Humanos , Isquemia Miocárdica/terapiaRESUMEN
Commentary on: McMurray JJV, Solomon SD, Inzucchi SE, et al Dapagliflozin in patients with heart failure and reduced ejection fraction. N Engl J Med 2019;381:1995-2008. Commentary by: Dr Joshua Au Yeunga, Clinical Pharmacology, St Thomas' Hospital, London, UK and Dr Teck Khong, Clinical Pharmacology, St George's, University of London, UK. Series Editor: Dr Teck Khong, DTB Associate Editor, Clinical Pharmacology, St George's, University of London, UK.
Asunto(s)
Compuestos de Bencidrilo/uso terapéutico , Glucósidos/uso terapéutico , Insuficiencia Cardíaca/tratamiento farmacológico , Insuficiencia Cardíaca/epidemiología , Hospitalización/estadística & datos numéricos , Anciano , Diabetes Mellitus/epidemiología , Femenino , Insuficiencia Cardíaca/mortalidad , Humanos , Enfermedades Renales/epidemiología , Masculino , Persona de Mediana Edad , Inhibidores del Cotransportador de Sodio-Glucosa 2RESUMEN
Commentary on: Mehta SR, Wood DA, Storey RF, et al Complete Revascularization with Multivessel PCI for Myocardial Infarction. N Engl J Med 2019; 381:1411-21. Commentary by: Dr Emma Magavern and Dr Teck Khong Clinical Pharmacology, St George's, University of London, UK. Series Editor: Dr Teck Khong, DTB Associate Editor Clinical Pharmacology, St George's, University of London, UK.
Asunto(s)
Intervención Coronaria Percutánea , Infarto del Miocardio con Elevación del ST , HumanosRESUMEN
Commentary on: Wiviott SD, Raz I, Bonaca MP, et al Dapagliflozin and cardiovascular outcomes in type 2 diabetes. N Engl J Med 2019;380:347-57. Commentary by: Dr Emma Magavern and Dr Teck Khong Clinical Pharmacology, St George's, University of London, UK Series Editor: Dr Teck Khong, DTB Associate Editor Clinical Pharmacology, St George's, University of London, UK.
Asunto(s)
Enfermedades Cardiovasculares , Diabetes Mellitus Tipo 2 , Compuestos de Bencidrilo , Glucósidos , HumanosRESUMEN
Commentary by: Dr James Kimpton and Dr Teck Khong Clinical Pharmacology, St George's, University of London, UKSeries Editor: Dr Teck Khong, DTB Associate Editor Clinical Pharmacology, St George's, University of London, UKCommentary on: Kraus WE, Bhapkar M, Huffman KM, et al 2 years of calorie restriction and cardiometabolic (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial. Lancet Diabetes Endocrinol 2019; 7: 673-83.
Asunto(s)
Restricción Calórica , Factores de Riesgo Cardiometabólico , Humanos , Calidad de VidaRESUMEN
Commentary on: Zeng C, Dubreuil M, LaRochelle MR, et al Association of tramadol with all-cause mortality among patients with osteoarthritis. JAMA 2019;321:969-82 Commentary by: Dr Catrin Page and Dr Teck Khong Clinical Pharmacology, St George's, University of London, UK Series Editor: Dr Teck Khong, DTB Associate Editor Clinical Pharmacology, St George's, University of London, London, UK.
Asunto(s)
Osteoartritis , Tramadol , Humanos , LondresRESUMEN
Commentary on: Narayan SW, Pearson SA, Litchfield M, et al Anticholinergic medicines use among older adults before and after initiating dementia medicines. BJCP 2019;85:1957-1963.Commentary by: Dr Christopher JD Threapleton and Dr Teck Khong, Clinical Pharmacology, St George's, University of London, UKSeries Editor: Dr Teck Khong, DTB Associate Editor, Clinical Pharmacology, St George's, University of London, London, UK.
Asunto(s)
Antagonistas Colinérgicos , Demencia , Anciano , HumanosRESUMEN
DTB commentaries provide an overview of, and commentary on, a clinical trial, systematic review or observational study.