Hypercoagulable disorders can compromise success of free flap reconstruction. Factor V Leiden is one such disorder for which only one previously reported case of successful free tissue transfer in the head and neck has been described. We report a 70-year-old woman with factor V Leiden treated for stage IVA squamous cell carcinoma of the mandible with a composite resection and reconstruction with an osteocutaneous scapular free tissue transfer. The free tissue transfer occurred without complications, in the setting of intraoperative heparin, postoperative aspirin, and enoxaparin. The free tissue transfer continues to be viable at her most recent follow-up appointment. The hypercoagulable patient represents a diverse presentation of increased coagulation risk in the perioperative period. Considering a patient's history and understanding available treatment adjuncts can factor heavily in a patient with factor V Leiden successfully undergoing free tissue transfer for head and neck defects.
Factor V , Postoperative Complications , Aged , Factor V/genetics , Female , Humans , Neck , Postoperative Complications/etiology , Retrospective Studies
Bone Density Conservation Agents/adverse effects , Diphosphonates/adverse effects , Mandibular Diseases/chemically induced , Osteonecrosis/chemically induced , Plastic Surgery Procedures/methods , Bone Plates , Bone Transplantation/methods , Breast Neoplasms/drug therapy , Carcinoma/drug therapy , Female , Follow-Up Studies , Humans , Imidazoles/adverse effects , Mandibular Diseases/surgery , Middle Aged , Osteonecrosis/surgery , Pamidronate , Surgical Flaps , Zoledronic Acid
Myositis Ossificans/pathology , Pterygoid Muscles/pathology , Adult , Female , Humans , Myositis Ossificans/complications , Myositis Ossificans/diagnostic imaging , Myositis Ossificans/surgery , Occlusal Splints , Pterygoid Muscles/diagnostic imaging , Pterygoid Muscles/surgery , Range of Motion, Articular , Recurrence , Tomography, X-Ray Computed , Trismus/etiology
