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1.
Harefuah ; 161(4): 207-209, 2022 Apr.
Artículo en Hebreo | MEDLINE | ID: mdl-35466602

RESUMEN

INTRODUCTION: The little fire ant (LFA) is an invasive ant species, increasingly found in wide distribution in Israel. Although it's sting is painful and itchy, for the most part, no serious adverse effects have been reported so far. We describe the case of a young boy with recurrent, life threatening anaphylactic reactions after stings, all occurring during the summer months, in areas where LFA infestations have been identified. An ad hoc skin test, developed with the cooperation of the allergy and entomology team, identified an immediate IgE-mediated reaction to LFA whole body extract, present in our patients and absent in healthy controls. This report may be the first identifying the LFA as a potential cause of severe anaphylactic reactions, but unfortunately, given the wide spread of these pests, it may be that such unrecognized reactions have already been treated by medical teams and misclassified as idiopathic anaphylaxis.


Asunto(s)
Anafilaxia , Anafilaxia/diagnóstico , Anafilaxia/etiología , Humanos , Israel , Masculino , Pruebas Cutáneas/efectos adversos
2.
Isr Med Assoc J ; 24(1): 11-14, 2022 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-35077039

RESUMEN

BACKGROUND: Emergency surgical repair is the standard approach to the management of an incarcerated abdominal wall hernia (IAWH). In cases of very high-risk patients, manual closed reduction (MCR) of IAWH may prevent the need for emergency surgery. OBJECTIVES: To evaluate the safety, success rate, and complications of MCR in the management of IAWH conducted in an emergency department. METHODS: The data of all patients who underwent MCR between 2012 and 2018 were retrospectively collected. Patient demographics, presenting symptoms, clinical parameters, and management during the hospitalization were retrieved from the medical charts. RESULTS: Overall, 548 patients underwent MCR during the study period. The success rate was 25.4% (139 patients). One patient had a complication that required a laparotomy 2 days after his discharge. A recurrent incarceration occurred in 23%, 60% of them underwent successful repeated MCR and the others underwent emergency surgery. Six patients (1.4%) had a bowel perforation after a failed MCR. CONCLUSIONS: MCR can be performed safely in the emergency department and should be consider as an option to treat IAWH, especially in high operative risk patients.


Asunto(s)
Hernia Abdominal , Herniorrafia , Perforación Intestinal , Laparotomía , Complicaciones Posoperatorias , Servicios Médicos de Urgencia/métodos , Servicio de Urgencia en Hospital/estadística & datos numéricos , Femenino , Hernia Abdominal/complicaciones , Hernia Abdominal/diagnóstico , Hernia Abdominal/epidemiología , Hernia Abdominal/cirugía , Herniorrafia/efectos adversos , Herniorrafia/métodos , Herniorrafia/estadística & datos numéricos , Humanos , Perforación Intestinal/diagnóstico , Perforación Intestinal/etiología , Perforación Intestinal/cirugía , Israel/epidemiología , Laparotomía/efectos adversos , Laparotomía/métodos , Masculino , Persona de Mediana Edad , Evaluación de Procesos y Resultados en Atención de Salud , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/cirugía , Reoperación/métodos , Reoperación/estadística & datos numéricos , Estudios Retrospectivos , Ajuste de Riesgo/métodos , Factores de Riesgo
4.
Isr Med Assoc J ; 23(10): 639-645, 2021 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-34672446

RESUMEN

BACKGROUND: Extra peritoneal packing (EPP) is a quick and highly effective method to control pelvic hemorrhage. OBJECTIVES: To determine whether EPP can be as safely and efficiently performed in the emergency department (ED) as in the operating room (OR). METHODS: Retrospective study of 29 patients who underwent EPP in the ED or OR in two trauma centers in Israel 2008-2018. RESULTS: Our study included 29 patients, 13 in the ED-EPP group and 16 in the OR-EPP group. The mean injury severity score (ISS) was 34.9 ± 11.8. Following EPP, hemodynamic stability was successfully achieved in 25 of 29 patients (86.2%). A raise in the mean arterial pressure (MAP) with a median of 25 mmHg (mean 30.0 ± 27.5, P < 0.001) was documented. All patients who did not achieve hemodynamic stability after EPP had multiple sources of bleeding or fatal head injury and eventually succumbed. Patients who underwent EPP in the ED showed higher change in MAP (P = 0.0458). The overall mortality rate was 27.5% (8/29) with no difference between the OR and ED-EPP. No differences were found between ED and OR-EPP in the amount of transfused blood products, surgical site infections, and length of stay in the hospital. However, patients who underwent ED-EPP were more prone to develop deep vein thrombosis (DVT): 50% (5/10) vs. 9% (1/11) in ED and OR-EPP groups respectively (P = 0.038). CONCLUSIONS: EPP is equally effective when performed in the ED or OR with similar surgical site infection rates but higher incidence of DVT.


Asunto(s)
Exsanguinación , Fracturas Óseas , Hemostasis Quirúrgica , Pelvis , Complicaciones Posoperatorias , Infección de la Herida Quirúrgica , Trombosis de la Vena , Determinación de la Presión Sanguínea/métodos , Servicio de Urgencia en Hospital/estadística & datos numéricos , Exsanguinación/diagnóstico , Exsanguinación/etiología , Exsanguinación/mortalidad , Exsanguinación/cirugía , Femenino , Fracturas Óseas/complicaciones , Fracturas Óseas/diagnóstico , Fracturas Óseas/cirugía , Hemostasis Quirúrgica/efectos adversos , Hemostasis Quirúrgica/instrumentación , Hemostasis Quirúrgica/métodos , Humanos , Puntaje de Gravedad del Traumatismo , Israel/epidemiología , Masculino , Persona de Mediana Edad , Evaluación de Procesos y Resultados en Atención de Salud , Pelvis/diagnóstico por imagen , Pelvis/lesiones , Complicaciones Posoperatorias/diagnóstico , Complicaciones Posoperatorias/epidemiología , Estudios Retrospectivos , Infección de la Herida Quirúrgica/diagnóstico , Infección de la Herida Quirúrgica/etiología , Centros Traumatológicos/estadística & datos numéricos , Trombosis de la Vena/diagnóstico , Trombosis de la Vena/etiología
5.
Isr Med Assoc J ; 23(2): 82-86, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33595211

RESUMEN

BACKGROUND: The novel coronavirus disease (COVID-19) pandemic changed medical environments worldwide. OBJECTIVES: To evaluate the impact of the COVID-19 pandemic on trauma-related visits to the emergency department (ED). METHODS: A single tertiary center retrospective study was conducted that compared ED attendance of patients with injury-related morbidity between March 2020 (COVID-19 outbreak) and pre-COVID-19 periods: February 2020 and the same 2 months in 2018 and 2019. RESULTS: Overall, 6513 patients were included in the study. During the COVID-19 outbreak, the daily number of patients visiting the ED for acute trauma declined by 40% compared to the average in previous months (P < 0.01). A strong negative correlation was found between the number of trauma-related ED visits and the log number of confirmed cases of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in Israel (Pearson's r = -0.63, P < 0.01). In the COVID-19 period there was a significant change in the proportion of elderly patients (7% increase, P = 0.002), admissions ratio (12% increase, P < 0.001), and patients brought by emergency medical services (10% increase, P < 0.001). The number of motor vehicle accident related injury declined by 45% (P < 0.01). CONCLUSIONS: A significant reduction in the number of trauma patients presenting to the ED occurred during the COVID-19 pandemic, yet trauma-related admissions were on the rise.


Asunto(s)
COVID-19/epidemiología , Servicio de Urgencia en Hospital/estadística & datos numéricos , Hospitalización/estadística & datos numéricos , Heridas y Lesiones/epidemiología , Accidentes de Tránsito/estadística & datos numéricos , Adolescente , Adulto , Distribución por Edad , Anciano , Estudios Transversales , Servicios Médicos de Urgencia/estadística & datos numéricos , Femenino , Humanos , Israel/epidemiología , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Centros de Atención Terciaria , Heridas y Lesiones/terapia , Adulto Joven
6.
Isr Med Assoc J ; 11(22): 673-679, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-33249785

RESUMEN

BACKGROUND: As part of the effort to control the coronavirus disease-19 (COVID-19) outbreak, strict emergency measures, including prolonged national curfews, have been imposed. Even in countries where healthcare systems still functioned, patients avoided visiting emergency departments (EDs) because of fears of exposure to COVID-19. OBJECTIVES: To describe the effects of the COVID-19 outbreak on admissions of surgical patients from the ED and characteristics of urgent operations performed. METHODS: A prospective registry study comparing all patients admitted for acute surgical and trauma care between 15 March and 14 April 2020 (COVID-19) with patients admitted in the parallel time a year previously (control) was conducted. RESULTS: The combined cohort included 606 patients. There were 25% fewer admissions during the COVID-19 period (P < 0.0001). The COVID-19 cohort had a longer time interval from onset of symptoms (P < 0.001) and presented in a worse clinical condition as expressed by accelerated heart rate (P = 0.023), leukocyte count disturbances (P = 0.005), higher creatinine, and CRP levels (P < 0.001) compared with the control cohort. More COVID-19 patients required urgent surgery (P = 0.03) and length of ED stay was longer (P = 0.003). CONCLUSIONS: During the COVID-19 epidemic, fewer patients presented to the ED requiring acute surgical care. Those who did, often did so in a delayed fashion and in worse clinical condition. More patients required urgent surgical interventions compared to the control period. Governments and healthcare systems should emphasize to the public not to delay seeking medical attention, even in times of crises.


Asunto(s)
Enfermedad Aguda , COVID-19 , Servicio de Urgencia en Hospital , Tratamiento de Urgencia , Control de Infecciones , Procedimientos Quirúrgicos Operativos , Heridas y Lesiones/cirugía , Enfermedad Aguda/epidemiología , Enfermedad Aguda/terapia , COVID-19/epidemiología , COVID-19/prevención & control , Servicio de Urgencia en Hospital/organización & administración , Servicio de Urgencia en Hospital/tendencias , Tratamiento de Urgencia/métodos , Tratamiento de Urgencia/estadística & datos numéricos , Femenino , Humanos , Control de Infecciones/métodos , Control de Infecciones/organización & administración , Israel/epidemiología , Masculino , Persona de Mediana Edad , Innovación Organizacional , Sistema de Registros/estadística & datos numéricos , SARS-CoV-2 , Índice de Severidad de la Enfermedad , Procedimientos Quirúrgicos Operativos/métodos , Procedimientos Quirúrgicos Operativos/estadística & datos numéricos , Tiempo de Tratamiento/tendencias , Heridas y Lesiones/epidemiología
7.
J Laparoendosc Adv Surg Tech A ; 30(9): 1001-1007, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32589496

RESUMEN

Introduction: Emergency departments (EDs) during the novel coronavirus disease 2019 (COVID-19) pandemic are perceived as possible sources of infection. The effects of COVID-19 on patients presenting to the hospital with surgical complaints remain uncertain. Methods: A single tertiary center retrospective study analysis compared the ED attendance rate and severity of patients with surgical complaints between March 2020 (COVID-19 outbreak) and pre-COVID-19 periods: February 2020 and the same 2 months in 2019 and 2018. Results: Overall, 6,017 patients were included. The mean daily ED visits of patients with nontrauma surgical complaints in the COVID-19 outbreak period declined by 27%-32% (P value <.01) compared with pre-COVID-19 periods. The log number of confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cases in Israel in March 2020 was negatively correlated with the number of ED visits (Pearson's r = -0.59, P < .01). The proportion of patients requiring hospitalization increased by up to 8% during the outbreak period (P < .01), and there was a higher proportion of tachycardic patients (20% versus 15.5%, P = .01). The percentage of visits to the ED by men declined by 5% (P < .01). The ED diagnosis distribution significantly changed during COVID-19 (P = .013), with an 84% decrease in the number of patients hospitalized for diverticular disease (P < .05). Conclusion: During the COVID-19 outbreak, the overall number of patients presenting at the ED with surgical complaints decreased significantly, and there was a higher admissions ratio. The extent to which the pandemic affects hospital ED attendance can help health care professionals prepare for future such events. ClinicalTrials.gov ID: NCT04338672.


Asunto(s)
Infecciones por Coronavirus/epidemiología , Servicio de Urgencia en Hospital/estadística & datos numéricos , Neumonía Viral/epidemiología , Servicio de Cirugía en Hospital/estadística & datos numéricos , Centros de Atención Terciaria/estadística & datos numéricos , Adolescente , Adulto , Anciano , Betacoronavirus , COVID-19 , Femenino , Personal de Salud , Hospitalización , Humanos , Enfermedades Intestinales/epidemiología , Israel/epidemiología , Masculino , Persona de Mediana Edad , Pandemias , Estudios Retrospectivos , SARS-CoV-2 , Factores Sexuales , Taquicardia/epidemiología , Adulto Joven
9.
Rom J Anaesth Intensive Care ; 27(2): 1-5, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-34056126

RESUMEN

BACKGROUND: Septic events complicated by hemodynamic instability can lead to decreased organ perfusion, multiple organ failure, and even death. Acute renal failure is a common complication of sepsis, affecting up to 50-70 % of cases, and it is routinely diagnosed by close monitoring of urine output. We postulated that analysis of the minute-to-minute changes in the urine flow rate (UFR) and also of the changes in its minute-to-minute variability might lead to earlier diagnosis of renal failure. We accordingly analyzed the clinical significance of these two parameters in a group of critically ill patients suffering from new septic events. METHODS: The study was retrospective and observational. Demographic and clinical data were extracted from the hospital records of 50 critically ill patients who were admitted to a general intensive care unit (ICU) and developed a new septic event characterized by fever with leukocytosis or leukopenia. On admission to the ICU, a Foley catheter was inserted into the urinary bladder of each patient. The catheter was then connected to an electronic urinometer - a collecting and measurement system that employs an optical drop detector to measure urine flow. Urine flow rate variability (UFRV) was defined as the change in UFR from minute to minute. RESULTS: Both the minute-to-minute UFR and the minute-to-minute UFRV decreased significantly immediately after each new septic episode, and they remained low until fluid resuscitation was begun (p < 0.001 for both parameters). Statistical analysis by the Pearson method demonstrated a strong direct correlation between the decrease in UFR and the decrease in the systemic mean arterial pressure (MAP) (R = 0.03, p = 0.003) and between the decrease in UFRV and the decrease in the MAP (R = 0.03, p = 0.004). Additionally, both the UFR and the UFRV demonstrated good responses to fluid administration prior to improvement in the MAP. CONCLUSION: We consider that minute-to-minute changes in UFR and UFRV could potentially serve as early and sensitive signals of clinical deterioration during new septic events in critically ill patients. We also suggest that these parameters might be able to identify the optimal endpoint for the administration of fluid resuscitative measures in such patients.

10.
Eur J Trauma Emerg Surg ; 46(5): 1175-1181, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-30758536

RESUMEN

PURPOSE: Dynamic changes in urine output and neurological status are the recognized clinical signs of hemodynamically significant hemorrhage. In the present study, we analyzed the dynamic minute-to-minute changes in the UFR and also the changes in its minute-to-minute variability in a group of critically ill multiple trauma patients whose blood pressures were normal on admission to the ICU but who subsequently developed hypotension within the first few hours of their ICU admission. PATIENTS AND METHODS: The study was retrospective and observational. Demographic and clinical data were extracted from the computerized register information systems initially; the clinical and laboratory data of 100 critically ill patients with multiple trauma who were admitted to the ICU during the study period were analyzed. Of this group, ten patients were eventually included in the study on the basis of the inclusion criteria. RESULTS: The minute-to-minute urine flow rate (UFR) and urine flow rate variability (UFRV) both decreased significantly during the periods of hypotension (p values 0.001 and 0.006, respectively). Notably, the decrease in UFRV preceded by at least 30 min a corresponding decline in the systolic and mean arterial blood pressures, which manifested as a flattening of UFRV amplitude which was observed prior to the occurrence of the lowest recorded systolic and mean arterial blood pressures. Statistical analysis by the Pearson method demonstrated a strong direct correlation between the decrease in UFRV and the decrease in the MAP (R = 0.9, p = 0.001), and SBP (R = 0.86, p = 0.001) and the decreasing urine output per hour (R = 0.88, p < 0.001). CONCLUSION: We found that changes in UFRV correlate strongly with systolic and mean arterial blood pressures. We feel that this parameter could potentially serve as an early signal of hemodynamic deterioration due to occult bleeding in critically ill trauma patients, and might also be able to identify the optimal end-point of hemodynamic resuscitative measures in these patients.


Asunto(s)
Enfermedad Crítica , Hipotensión/orina , Traumatismo Múltiple/orina , Micción , APACHE , Adulto , Femenino , Humanos , Puntaje de Gravedad del Traumatismo , Israel , Masculino , Estudios Retrospectivos , Signos Vitales
11.
Traffic Inj Prev ; 20(5): 540-543, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31157559

RESUMEN

Objective: The objective of this study was to conduct a comprehensive analysis of demographics, injury characteristics and hospital resource utilization of significant pediatric electric bicycle (e-bike) injuries leading to hospitalization following an emergency department visit in comparison to pediatric injuries caused by other traffic related mechanisms. Methods: A retrospective review of all pediatric traffic injury hospitalizations following an emergency department visit to a level I trauma center between October 2014 and September 2016 was conducted. Data regarding age, sex, number of computed tomography (CT) scans obtained, number of major procedures, length of hospital stay (LOS), Injury Severity Score (ISS), and number of injuries per patient were collected and compared between e-bike injuries and other traffic injuries. Results: Three hundred thirty-seven admissions were analyzed: 46 (14%) were due to e-bike injuries (29% of patients >12 years). Age, proportion of brain injuries, and use of CT were significantly increased compared to mechanical bicycle injuries (13.1 ± 3.4 vs. 10.6 ± 3.6, 13% vs. 3%, 1 [0-3] vs. 1 [0-1], P < .01, P = .03, P = .05). Age, LOS, and use of CT were significantly increased compared to injuries caused to automobile passengers (13.1 ± 3.4 vs. 7.4 ± 5.3, 1 [1-3] vs. 1 [1-2], 1 [0-3] vs. 0 [0-1], P < .01, P = .03, P = .01), as well as ISS and number of injuries per patient (P = .04, P < .01). Injuries caused by e-bikes were similar to injuries caused to pedestrians, except for age (13.1 ± 3.4 vs. 8.5 ± 3.7, P < .01). Multivariable analysis revealed a significant association between mechanism of injury and ISS, with increased ISS among e-bike injuries compared to mecahnical bike injuries (OR 2.56, CI 1.1-5.88, P = 0.03) and automobile injuries (OR 4.16, CI 1.49-12.5, (P < .01). Conclusion: E-bikes are a significant cause of severe injury in children compared to most other traffic injuries, particularly in older children.


Asunto(s)
Accidentes de Tránsito/estadística & datos numéricos , Ciclismo/lesiones , Heridas y Lesiones/epidemiología , Adolescente , Ciclismo/estadística & datos numéricos , Niño , Electricidad , Humanos , Estudios Retrospectivos
12.
Harefuah ; 158(4): 253-257, 2019 Apr.
Artículo en Hebreo | MEDLINE | ID: mdl-31032559

RESUMEN

INTRODUCTION: The therapeutic approach to diverticular disease has changed significantly in recent decades. From a disease treated almost exclusively by surgery, diverticulitis is nowadays treated operatively in specific indications, shifting the majority of patients towards an outpatient based treatment. Significant changes occurred not only in uncomplicated diverticular disease but also in complicated cases, treated in the past with emergency surgery. These changes have been studied relentlessly around the world, and despite the fact that the vast majority of patients presenting with acute diverticular disease are not treated with surgery, it is still considered a surgical condition. In this review article, we set out to examine whether there is still justification to consider acute diverticulitis as a surgical disease and in addition, to examine whether the changes in treatment seen around the world are compatible with the current treatment strategies implemented in Israel.


Asunto(s)
Enfermedades Diverticulares , Diverticulitis , Enfermedad Aguda , Enfermedades Diverticulares/cirugía , Diverticulitis/cirugía , Humanos , Israel
13.
J Trauma Acute Care Surg ; 86(1): 108-115, 2019 01.
Artículo en Inglés | MEDLINE | ID: mdl-30358770

RESUMEN

BACKGROUND: Hemorrhage is the most common preventable cause of death in both civilian and military trauma. There is no consensus regarding the appropriate fluid resuscitation protocol. Plasma, as a resuscitative fluid, has substantial benefits as a volume expander, owing to its relatively high oncotic pressure and its positive effect on trauma-induced coagulopathy by replenishing the lost coagulation factors, rather than diluting the casualty's remaining factors. The Israel Defense Force Medical Corps decided to use freeze-dried plasma (FDP) as the fluid of choice for casualties in hemorrhagic shock in the prehospital setting. The aim of our study is to compare the differences of coagulation, perfusion measurements, resource utilization, and outcome between casualties receiving FDP to casualties who did not receive FDP in the prehospital setting. METHODS: This is a retrospective matched cohort study based on two groups of casualties (those treated with FDP vs. those without FDP treatment). The control group was compiled in three steps of precision for age, sex, mechanism of injury and maximum level of severity for each nine injured body regions. Data were collected from the IDF Trauma Registry and The National Israel Trauma Registry. RESULTS: The study group comprised 48 casualties receiving FDP and 48 controls with no differences in demographic, evacuation time, and injury characteristics. The FDP group demonstrated a lower level of hemoglobin (12.7 gr/dzl) (odds ratio [OR], 3.11; 95% confidence interval [CI], 1.10-8.80), lower level of international normalized ratio (1.1) (OR, 3.09; 95% CI, 1.04-9.14), and lower level of platelets (230 × 109/L) (OR, 3.06; 95% CI, 1.16-8.06). No other differences were found between the two groups. CONCLUSION: The use of FDP in the prehospital setting has logistic benefits and a positive effect on coagulation profile, with no other significant effects. Future studies need to be performed on larger groups to verify trends or nullify our hypotheses. LEVEL OF EVIDENCE: Therapeutic, level IV.


Asunto(s)
Liofilización/métodos , Hemorragia/terapia , Choque Hemorrágico/terapia , Heridas y Lesiones/complicaciones , Adolescente , Adulto , Coagulación Sanguínea/fisiología , Trastornos de la Coagulación Sanguínea/fisiopatología , Trastornos de la Coagulación Sanguínea/terapia , Estudios de Casos y Controles , Causas de Muerte , Servicios Médicos de Urgencia/métodos , Femenino , Fluidoterapia/métodos , Hemorragia/prevención & control , Humanos , Puntaje de Gravedad del Traumatismo , Israel/epidemiología , Masculino , Personal Militar , Plasma , Sistema de Registros , Resucitación/métodos , Resucitación/tendencias , Estudios Retrospectivos , Heridas y Lesiones/epidemiología , Heridas y Lesiones/mortalidad , Adulto Joven
15.
World J Emerg Surg ; 12: 41, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28828035

RESUMEN

BACKGROUND: The urine output is an important clinical parameter of renal function and blood volume status, especially in critically ill multiple trauma patients. In the present study, the minute-to-minute urine flow rate and its variability were analyzed in hypotensive multiple trauma patients during the first 6 h of their ICU (intensive care unit) stay. These parameters have not been previously reported. METHODS: The study was retrospective and observational. Demographic and clinical data were extracted from the computerized Register Information Systems. A total of 59 patients were included in the study. The patients were divided into two study groups. Group 1 consisted of 29 multiple trauma patients whose systolic blood pressure was greater than 90 mmHg on admission to the ICU and who were consequently deemed to be hemodynamically compromised. Group 2 consisted of 30 patients whose systolic blood pressure was less than 90 mmHg on admission to the ICU and who were therefore regarded as hemodynamically uncompromised. RESULTS: The urine output and urine flow rate variability during the first 6 h of the patients' ICU stay was significantly lower in group 2 than in group 1 (p < 0.001 and 0.006 respectively). Statistical analysis by the Pearson method demonstrated a strong direct correlation between decreased urine flow rate variability and decreased urine output per hour (R = 0.17; P = 0.009), decreased mean arterial blood pressure (R = 0.24; p = 0.001), and increased heart rate (R = 0.205; p = 0.001). CONCLUSION: These findings suggest that minute-to-minute urine flow rate variability is a reliable incipient marker of hypovolemia and that it should therefore take its place among the parameters used to monitor the hemodynamic status of critically ill multiple trauma patients.


Asunto(s)
Flujómetros , Hipovolemia/diagnóstico , Monitoreo Fisiológico/normas , Traumatismo Múltiple/terapia , Orina/fisiología , APACHE , Adulto , Gasto Cardíaco/fisiología , Femenino , Hemodinámica/fisiología , Humanos , Hipovolemia/fisiopatología , Puntaje de Gravedad del Traumatismo , Masculino , Persona de Mediana Edad , Monitoreo Fisiológico/métodos , Traumatismo Múltiple/clasificación , Traumatismo Múltiple/diagnóstico , Estudios Retrospectivos , Centros Traumatológicos/organización & administración , Centros Traumatológicos/estadística & datos numéricos
16.
JAMA Surg ; 151(10): 954-958, 2016 10 01.
Artículo en Inglés | MEDLINE | ID: mdl-27409973

RESUMEN

Importance: Head injury following explosions is common. Rapid identification of patients with severe traumatic brain injury (TBI) in need of neurosurgical intervention is complicated in a situation where multiple casualties are admitted following an explosion. Objective: To evaluate whether Glasgow Coma Scale (GCS) score or the Simplified Motor Score at presentation would identify patients with severe TBI in need of neurosurgical intervention. Design, Setting, and Participants: Analysis of clinical data recorded in the Israel National Trauma Registry of 1081 patients treated following terrorist bombings in the civilian setting between 1998 and 2005. Primary analysis of the data was conducted in 2009, and analysis was completed in 2015. Main Outcomes and Measures: Proportion of patients with TBI in need of neurosurgical intervention per GCS score or Simplified Motor Score. Results: Of 1081 patients (median age, 29 years [range, 0-90 years]; 38.9% women), 198 (18.3%) were diagnosed as having TBI (48 mild and 150 severe). Severe TBI was diagnosed in 48 of 877 patients (5%) with a GCS score of 15 and in 99 of 171 patients (58%) with GCS scores of 3 to 14 (P < .001). In 65 patients with abnormal GCS (38%), no head injury was recorded. Nine of 877 patients (1%) with a GCS score of 15 were in need of a neurosurgical operation, and fewer than 51 of the 171 patients (30%) with GCS scores of 3 to 14 had a neurosurgical operation (P < .001). No difference was found between the proportion of patients in need of neurosurgery with GCS scores of 3 to 8 and those with GCS scores of 9 to 14 (30% vs 27%; P = .83). When the Simplified Motor Score and GCS were compared with respect to their ability to identify patients in need of neurosurgical interventions, no difference was found between the 2 scores. Conclusions and Relevance: Following an explosion in the civilian setting, 65 patients (38%) with GCS scores of 3 to 14 did not experience severe TBI. The proportion of patients with severe TBI and severe TBI in need of a neurosurgical intervention were similar in patients presenting with GCS scores of 3 to 8 and GCS scores of 9 to 14. In this study, GCS and Simplified Motor Score did not help identify patients with severe TBI in need of a neurosurgical intervention.


Asunto(s)
Traumatismos por Explosión/diagnóstico , Traumatismos por Explosión/cirugía , Lesiones Traumáticas del Encéfalo/diagnóstico , Lesiones Traumáticas del Encéfalo/cirugía , Craneotomía/estadística & datos numéricos , Escala de Coma de Glasgow , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Explosiones , Femenino , Humanos , Lactante , Recién Nacido , Presión Intracraneal , Israel , Masculino , Persona de Mediana Edad , Monitoreo Fisiológico/estadística & datos numéricos , Evaluación de Necesidades , Terrorismo , Adulto Joven
17.
J Trauma Acute Care Surg ; 80(6): 985-8, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-26998779

RESUMEN

BACKGROUND: Semirigid cervical collars (SRCCs) are routinely applied to victims of explosions as part of the prehospital trauma protocols. Previous studies have shown that the use of SRCC in penetrating injuries is not justified because of the scarcity of unstable cervical spine injuries and the risk of obscuring other neck injuries. Explosion can inflict injuries by fragments penetration, blast injury, blunt force, and burns. The purpose of the study was to determine the occurrence of cervical spine instability without irreversible neurologic deficit and other potentially life-threatening nonskeletal neck injuries among victims of explosions. The potential benefits and risks of SRCC application in explosion-related injuries were evaluated. METHODS: This is a retrospective cohort study of all explosion civilian victims admitted to Israeli hospitals during the years 1998 to 2010. Data collection was based on the Israeli national trauma registry and the hospital records and included demographic, clinical, and radiologic details of all patients with documented cervical spine injuries. RESULTS: The cohort included 2,267 patients. All of them were secondary to terrorist attacks. SRCC was applied to all the patients at the scene. Nineteen patients (0.83%) had cervical spine fractures. Nine patients (0.088%) had unstable cervical spine injury. All but one had irreversible neurologic deficit on admission. A total of 151 patients (6.6%) had potentially life-threatening penetrating nonskeletal neck injuries. CONCLUSION: Unstable cervical spine injuries secondary to explosion are extremely rare. The majority of unstable cervical spine fractures were secondary to penetrating injuries, with irreversible neurologic deficits on admission. The application of SRCC did not seem to be of any benefit in these patients and might pose a risk of obscuring other neck injuries. We recommend that SRCC will not be used in the prehospital management of victims of explosions. LEVEL OF EVIDENCE: Prognostic/epidemiologic study, level III.


Asunto(s)
Traumatismos por Explosión/terapia , Tirantes , Explosiones , Inmovilización/instrumentación , Traumatismos del Cuello/terapia , Traumatismos Vertebrales/terapia , Heridas Penetrantes/terapia , Adolescente , Adulto , Traumatismos por Explosión/fisiopatología , Preescolar , Femenino , Humanos , Israel , Masculino , Persona de Mediana Edad , Traumatismos del Cuello/fisiopatología , Estudios Retrospectivos , Traumatismos Vertebrales/fisiopatología , Terrorismo , Heridas Penetrantes/fisiopatología
18.
Brain Inj ; 30(1): 83-9, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-26734841

RESUMEN

AIM: To assess the incidence and injury characteristics of hospitalized trauma patients diagnosed with TBI. METHODS: A retrospective study of all injured hospitalized patients recorded in the National Trauma Registry at 19 trauma centres in Israel between 2002-2011. Incidence and injury characteristics were examined among children, adults and seniors. RESULTS: The annual incidence rate of hospitalized TBI for the Israeli population in 2011 was 31.8/100,000. Age-specific incidence was highest among seniors with a dramatic decrease in TBI-related mortality rate among them. Adults, in comparison to children and seniors, had higher rates of severe TBI, severe and critical injuries, more admission to the intensive care unit, underwent surgery, were hospitalization for more than 2 weeks and were discharged to rehabilitation. After adjusting for age, gender, ethnicity, mechanism of injury and injury severity score, TBI-related in-hospital mortality was higher among seniors and adults compared to children. CONCLUSION: Seniors are at high risk for TBI-related in-hospital mortality, although adults had more severe and critical injuries and utilized more hospital resources. However, seniors showed the most significant reduction in mortality rate during the study period. Appropriate intervention programmes should be designed and implemented, targeted to reduce TBI among high risk groups.


Asunto(s)
Lesiones Traumáticas del Encéfalo/epidemiología , Accidentes de Tránsito/estadística & datos numéricos , Adolescente , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Lesiones Traumáticas del Encéfalo/prevención & control , Niño , Preescolar , Femenino , Mortalidad Hospitalaria , Humanos , Incidencia , Israel/epidemiología , Masculino , Persona de Mediana Edad , Estudios Retrospectivos
19.
Thromb Res ; 137: 26-29, 2016 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-26653366

RESUMEN

BACKGROUND: Cerebral sinus vein thrombosis (CSVT) is a rare disease with significant neurological sequelae and high mortality rate. Incidence of CSVT diagnosis in the western world has increased despite the reduced occurrence of infections. AIM: To identify risk factors that may explain the predisposition to site specific thrombosis. METHODS: Ninety consecutive patients diagnosed with acute CSVT in tertiary hospital. As a control group we used the data extracted from the National Trauma Registry and Healthcare Services. RESULTS: Trauma history up to one month prior to diagnosis of CVST was found in 13 (14%) patients. Six patients had skull fractures, the others had blunt trauma. The overall SMR was 941 (p<0.0001); the separate results for men and women were 1206 and 543, respectively. Infections confined to the head and neck in 7% of the cases and brain tumor were observed in 8%. At the time of CVST, 23 of 50 (46%) women had a hormonal risk factor. The SMR for OC use was 1.63 (p=0.0298). Prothrombotic polymorphisms were detected in 16 of 63 (25.4%) patients who were tested for factor V Leiden and prothrombin G20210A mutation (OR=3.47, p=0.002) in comparison to 49% in DVT patients (OR=9.95, p<0.0001). CONCLUSIONS: Assessment for CVST in patients with recent trauma and headache even after intact head CT is required. The other risk factors, such as hormone related and prothrombotic polymorphisms, were not specific just for CVST and the latter play a lesser role in CVST than in DVT.


Asunto(s)
Traumatismos Craneocerebrales/epidemiología , Traumatismos Craneocerebrales/genética , Traumatismos del Cuello/epidemiología , Traumatismos del Cuello/genética , Trombosis de los Senos Intracraneales/epidemiología , Trombosis de los Senos Intracraneales/genética , Adulto , Distribución por Edad , Factores de Coagulación Sanguínea/genética , Causalidad , Comorbilidad , Femenino , Predisposición Genética a la Enfermedad/epidemiología , Predisposición Genética a la Enfermedad/genética , Humanos , Incidencia , Israel/epidemiología , Masculino , Persona de Mediana Edad , Factores de Riesgo , Distribución por Sexo
20.
Mil Med ; 180(12): 1211-3, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-26633663

RESUMEN

Tension pneumothorax is one of the leading causes of preventable death in trauma patients. Needle thoracotomy (NT) is the currently accepted first-line intervention but has not been well validated. In this review, we have critically discussed the evidence for NT procedure, re-examined the recommendations by the Advanced Trauma Life Support organization and investigated the safest and most effective way of NT. The current evidence to support the use of NT is limited. However, when used, it should be applied in the 2nd intercostal space at midclavicular line using a catheter length of at least 4.5 cm. Alternative measures should be studied for better prehospital management of tension pneumothorax.


Asunto(s)
Pulmón/fisiopatología , Neumotórax/cirugía , Toracotomía , Humanos , Lesión Pulmonar/complicaciones , Agujas , Neumotórax/etiología , Neumotórax/terapia , Guías de Práctica Clínica como Asunto , Toracostomía , Toracotomía/métodos , Heridas y Lesiones
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