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Tetrahedron
; 62(16): 3815-3822, 2006 Apr 17.
Artículo
en Inglés
| MEDLINE
| ID: mdl-21394235
RESUMEN
Ynamides react with ketenes in [2+2] cycloadditions leading to a variety of substituted 3-aminocyclobut-2-en-1-ones. The ynamides employed in these reactions are readily available via the copper-promoted N-alkynylation of carbamates and sulfonamides with alkynyl bromides and iodides. The scope of the [2+2] cycloaddition with regard to both the ketene and ynamide component is described.