1.
J Org Chem
; 74(10): 3962-5, 2009 May 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-19361186
RESUMEN
We report a new asymmetric synthetic method for (-)-swainsonine utilizing a chiral oxazoline precursor. The key features in this strategy are the diastereoselective oxazoline formation reaction catalyzed by palladium(0), diasteroselective dihydroxylation, and the stereocontrolled allylation reaction with TiCl(4).