[Significance of the determination of gonadotropic pituitary hormones in different types of autonomic vascular dystonia]. / Znachenie issledovaniia gonadotropnykh gormonov gipofiza i éstradiola pri razlichnykh tipakh vegetososudistoi distonii.

Measurements were made of the content of gonadotropic pituitary hormones (prolactin/PRL), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and estradiol in 151 children aged 11 to 15 years. Of these, there were 58 healthy children (24 boys and 34 girls), 51 children (25 boys and 26 girls) with vegetovascular dystonia (VVD) of the vagotonic type and 42 children (22 boys and 20 girls) with VVD of the sympathotonic type. It has been established that in VVD children, alterations in the hypothalamus-pituitary-gonadal system agreed with the general biological reactions of the body, while deviations in the LH and FSH levels as well as in estradiol got stabilized by 13 to 15 years. A positive correlation has been revealed between the high blood PRL level and the high tone of the sympathetic nervous system. In view of this fact the blood PRL content can serve an early diagnostic test for recognizing hypersympathicotonia in VVD children.

[Phleboscintigraphy in the diagnosis of diseases of leg veins]. / Flebostsintigrafiia v diagnostike zabolevanii ven nizhnikh konechnostei.

The authors worked out the methods of staged radionuclide phleboscintigraphy and defined its clinical importance for examination of patients with chronic venous insufficiency of the lower limbs using a gamma-chamber without an image synchronized with a moving table. Altogether 26 patients with various forms of lower limb venous insufficiency were examined. A normal phleboscintigram and radionuclide semiotics of the main lesions of the lower limb veins were described. The method of staged radionuclide phleboscintigraphy permits one to obtain a good image of the iliofemoral venous segment and vena cava inferior in minimum radiation exposure and traumatism.

[Complex evaluation of pancreatic function in insulin-dependent diabetes mellitus]. / Kompleksnaia otsenka funktsii podzheludochnoi zhelezy pri insulinozavisimom sakharnom diabete.

The time course of the concentration of immunoreactive insulin (IRI) and C-peptide in the plasma and erythrocytes and the blood sugar level in GTT per os were investigated. Altogether 73 healthy persons and 52 patients with a severe form of insulin-dependent diabetes mellitus were examined. To define the time course of changes in the concentration of the above values a rate gradient determined as a difference of changed concentration rate for the 1st and 2nd hour after load for each examined person, was proposed. The most significant differences in the healthy persons and patients were noted in the plasma IRI basal level and blood sugar basal levels. The rate gradient defined most completely the time course of carbohydrate metabolism. The gradients C-peptide had maximum difference in healthy persons and patients. The hormone and blood sugar levels characterized the condition of the examined persons, and rate gradients were indicative of the state of the blood sugar regulation system.