Erythroderma is a dermatological emergency presenting with generalized erythema and scaling involving <90% of the body surface.1 There are various causes of erythroderma, such as psoriasis, atopic dermatitis, phytophotodermatitis, pityriasis rubra pilaris, pemphigus foliaceus, cutaneous T-cell lymphoma, and drug eruptions.2 However, erythroderma induced by dermatophytosis is encountered rarely. We, here, describe a case of erythroderma developed secondary to extensive dermatophytosis.
Dermatitis, Exfoliative , Humans , Dermatitis, Exfoliative/etiology , Dermatitis, Exfoliative/diagnosis , Dermatitis, Exfoliative/drug therapy , Male , Tinea/diagnosis , Tinea/drug therapy , Antifungal Agents/therapeutic use , Middle Aged
Curcumin is a widely researched natural product and is known to possess anti-carcinogenic properties. Chronic lymphocytic leukemia is a type of leukemia that principally affects patients with age higher than 60 years. Since the toxicity of conventional drugs exceeds the benefits of treating this leukemia type, patients are treated only in the advanced symptomatic stages. The current article reviews curcumin, its general actions and targets in cancer, and specifically that of it in chronic lymphocytic leukemia.
Snake venoms are folk medicines used since ages. The components of snake venoms have high specific affinity and actions on cells and cell components. Also snake venoms are largely cytotoxic to tumor cells than normal cells. In addition to these, they have several therapeutic actions that make them an attractive option in the management of cancer. The advent of modern technologies has greatly helped in extracting and identifying new components of therapeutic interests in short time. The article highlights the importance of snake venoms in the management of cancer, so as to motivate curious researchers to devote their skills in this fascinating area. This in turn may bring hope, smile and relief to several cancer patients in future.
CONTEXT: There is paucity of data regarding the role of submental intubation (SI) in the airway management of patients with craniomaxillofacial trauma from India. AIMS: To study the characteristics of patients presenting with craniomaxillofacial injuries requiring submental intubation, the duration of SI procedure and complications of this technique. SETTINGS AND DESIGN: Tertiary level, teaching institute, retrospective, observational study. MATERIALS AND METHODS: Forty patients requiring submental intubation between June, 2007 and December, 2009. The primary outcome measure was the time required for submental intubation defined as starting from the completion of the orotracheal intubation to the fixation of the submental tube. The secondary outcome measures included characteristics of patients with craniomaxillofacial injuries, intraoperative and postoperative complications of the SI technique. STATISTICAL ANALYSIS USED: Data are presented as mean± standard deviation and frequency and percentages, where relevant. RESULTS: Most of the patients were young (average age = 35.15 ± 12.02 years), males (75%) and sustained craniomaxillofacial injuries due to road traffic accidents (85%). The 40 patients included in this audit had 56 injuries recorded at the time of admission including, orthopedic injuries in 65% and head injuries in 55% of patients. The mean time required for completion of SI was 8.90 min. The complications observed included, intraoperative tube migration, development of extra oral fistula, and sialocele, in one patient each. CONCLUSIONS: Submental intubation is a simple, safe, quick, and relatively harmless alternative to tracheostomy for securing the airway in selected patients with craniofacial trauma. Familiarity with the submental intubation technique will help the anesthesiologist to avoid tracheostomy in selected patients with craniofacial trauma who do not require long-term mechanical ventilation.
