1.
Bioorg Med Chem Lett
; 15(11): 2829-33, 2005 Jun 02.
Artículo
en Inglés
| MEDLINE
| ID: mdl-15911263
RESUMEN
The structure-based design, chemical synthesis, and biological evaluation of novel MTAP substrates are described. These compounds incorporate various C5'-moieties and are shown to have different k(cat)/K(m) values compared with the natural MTAP substrate (MTA).