RESUMEN
Recovery of mental health in people with schizophrenia spectrum disorders is essential, thus it is very important to be assessed. One instrument that measures mental health recovery is the Recovery Assessment Scale - Domains and Stages (RAS-DS), developed within the Australian cultural context to facilitate mental health recovery. An instrument based on conceptions of mental health recovery in Indonesia is still needed. This qualitative study aimed to characterise how persons with schizophrenia spectrum disorders in Indonesia define mental health recovery, to develop the Skala Pemulihan Pasien Skizofrenia (SPPS)/Indonesian Recovery Scale for Patient with Schizophrenia (I-RSPS), and to determine the content validity of the I-RSPS. Qualitative data were collected through focus group discussions (n = 11); data were analysed using conventional content analysis and thematic analysis. An inductive approach was used to develop the I-RSPS items. Content validity was evaluated using an item-level content validity index (I-CVI) and a scale-level content validity index (S-CVI). Validity evaluation trials were conducted with ten participants. Perceptions of mental health recovery in people with schizophrenia spectrum disorders in Indonesia were investigated along social, existential, clinical, functional, and physical dimensions. Some perceptions of family, religion, and spirituality are unique to the Indonesian socio-cultural context, as are some stigmas I-RSPS consists of 40 items with good content validity, with an average I-CVI of 0.99 and an average S-CVI of 0.93, and it was rated as easy to use, with 5.4 min (range: 3-10 min) being the average duration required to complete the scale.
RESUMEN
Introduction: This study aims to identify the psychosocial determinants and examine the mediation mechanisms of the compliance with COVID-19 health protocols among people undergoing isolation in health facilities that specifically treat COVID-19 cases in Jakarta, Indonesia. Methods: This is a cross-sectional study which used socio-cognitive approach, known as the Health Action Process Approach (HAPA), to understand the complexity of issues related to compliance with health protocols. A total of 1,584 subjects participated in this study, including 865 men and 719 women over the age of 18 years old during the data collection period (October 19-26, 2020). The data were collected using questionnaire that was developed by a team of experts from the Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo General Hospital, and survivors. The data that has been collected were then analyzed using Structural Equation Modeling, a multivariate data analysis technique. Results: The final research model in this study fulfills the criteria for a good model fit. This study found that individuals who have strong self-efficacy regarding their ability to implement behaviors and overcome obstacles will have stronger intent to comply in the future. The study also found that stronger intent will lead to stronger planning, and planning was found mediating intention and compliance with health protocols. Conclusion: This research model is comprehensive and useful in understanding compliance with health protocols among people undergoing isolation in health facilities for COVID-19 (Wisma Atlet and RSCM Kiara Ultimate). Having intent (related to the risk perception, outcome expectancies, and self-efficacy) and having a plan can positively influence the behavior of people undergoing isolation, resulting in better compliance to health protocols. The understanding gained from this study can be used to improve strategies related to compliance with health protocols against COVID-19 in the communities.
RESUMEN
PIP5K2A variants have been shown to be associated with schizophrenia in Caucasian populations. This study tested 12 PIP5K2A SNPs for association with schizophrenia in a sample of 152 sib-pair families of Indonesian descent. All SNPs had previously been tested for association with schizophrenia in a German family sample by Schwab et al. [2006; Mol Psychiatry] and seven SNPs were nominally associated with schizophrenia in this previous study. The purpose of the study was to examine whether previously implicated PIP5K2A variants influence susceptibility to schizophrenia in populations of non-European descent. No single markers showed nominal association with schizophrenia in this Indonesian family sample, however multi-marker haplotypes including a previously associated exonic SNP marker revealed nominally significant association (P = 0.03). Power to detect association was greater than 80% for all previously implicated variants except for rs11013052, where power was greatly reduced due to the low minor allele frequency of this marker in the Indonesian sample. An explorative study combining the results of this study with those of our previous study indicated that rs11013052 was significantly associated with schizophrenia in the combined sample (P = 0.002). The results of this study suggest that any contribution of previously implicated DNA variants within the PIP5K2A gene to schizophrenia susceptibility in the Indonesian population is only minor.
