[The content of Clara's cells protein in highly premature newborns with respiration disorders].

The study was carried out to analyze the content of Clara's cells protein in highly premature newborns with respiration disorders in neonatal period. The sample of 106 premature newborns of gestational age 26-32 weeks and body mass at birth 660-1500 g was examined. The concentration of Clara's cells protein in bronchoalveolar liquid and blood serum was higher in patients with inborn pneumonia as compared with children with respiratory distress syndrome. The low content Clara's cells protein in highly premature newborns with pneumonia was related with subsequent development of bronchopulmonary dysplasia.

[Urine cholinesterase activity in full-term neonatal infants with ischemic nephropathy].

To determine urine cholinesterase activity in full-term neonatal infants with varying ischemic nephropathy in an intensive care unit, the investigators studied this enzyme on days 1 and 5-7 of life, by using a kinetic photometric test optimized according to the Deutsche Gesellschaft fur Klinische Chemie (German Society for Clinical Chemistry) recommendations. In the early neonatal period, the newborns with grade III ischemic nephropathy were found to have a high urine cholinesterase activity. The determination of urine cholinesterase activity just on the first day of life may be used for the early diagnosis of grade III ischemic nephropathy in the newborns until the clinical manifestations of this pathology develop.

[Induced sperm plasma chemiluminescence as a new method for detection of antispermal antibodies].

Sperm plasma was studied by induced chemiluminescence in males with reproductive dysfunction (infertility, miscarriage) in married couples and in the presence of antispermal antibodies (ASAB) detected by latex agglutination. In ASAB-positive patients, the light sum was found to be increased and equal to 14.23 imp/sec or more. The chemiluminescence technique may be recommended as a method for detecting ASAB with an accuracy of 90.4%, with 94.1% specificity, and 88.6% sensitivity.

[Determination of medium-weight molecules in the plasma and urine of neonatal infants with ischemic nephropathy].

To ascertain the level of medium-weight molecules in the plasma and urine in critically ill neonatal infants with varying ischemic nephropathy, the authors determined the content of medium-weight molecules by N. I. Gabrielyan's procedure modified by M. Ya. Malakhova. Within the first 24 hours of life, the newborn infants with ischemic nephropathy had high plasma levels of medium-weight proteins. The high plasma levels of medium-weight molecules were attended by their urinary elimination in first- and second-grade ischemic nephropathy and these were not compensated for by their elimination in third-grade nephropathy, which was linked to decreased renal excretory function. The determination of medium-weight molecules in the plasma and urine permits identification of acute renal failure in the newborn.

[Some biochemical parameters in the placenta in discoordinated and powerless labors].

A number of biochemical parameters (total nitrites and nitrates (NO(x)), cyclic guanosine monophosphate (cGMP), nitrotyrosine, medium-weight molecules (MCM) in the placenta were determined in women with gestosis during discoordinated and powerless labor. Thirty placentas (10 placentas from parturients after discoordinated labor, 10 from those after powerless labor, 10 placentas as a control group) were examined. Changes in the parameters under study were found to result in the development of nitroxide and oxidant stresses and endotoxicosis. The biochemical parameters should be considered as placental criteria for the differential diagnosis of labor anomalies in gestosis, such as powerless and discoordinated labors.

[The levels of nitrites and medium molecular-weight molecules in the blood of neonatal infants with posthypoxic cardiopathy].

A hundred and four neonatal infants underwent clinical and functional studies in early neonatality. The levels of nitrites and medium molecular-weight molecules were determined in cardiologically healthy neonatal infants and children with posthypoxic cardiopathy. The magnitude of increases in biochemical parameters was found to be associated with clinical type of cardiopathy: their level significantly elevates in transient myocardial ischemia, their values achieve the maximum level in neonatal pulmonary hypertension and in the presence of functioning fetal communications.

[Complex clinical and laboratory characterization of hemostatic disorders in premature neonates with respiratory distress syndrome].

The pattern of time courses of changes in the basic parameters of homeostasis has been studied in premature neonates with respiratory disorders of varying severity in early neonatality. It is shown that in premature neonates with respiratory distress syndrome, all links of the hemostatic system occur and the activity of the major pool of anticoagulants (antithrombin III and protein C) decreases. The most informative indices are proposed for monitoring hemostatic parameters as determination of basic tests, the levels of protein C, D-dimer, and SFMC.

[Magnesium and calcium ion levels in peritoneal fluid of healthy fertile women]. / Kontsentratsiia ionov magniia i kal'tsiia v peritoneal'noi zhidkosti u zdorovykh fertil'nykh zhenshchin.

The purpose of this study was to establish normal values of Ca2+ and Mg2+ ions in the peritoneal fluid (PF) of fertile women. PF was aspirated during laparoscopy in 19 women subjected for surgical sterilization for social reasons. The concentrations of Ca2+ and Mg2+ in PF were normal. In fertile women the peritoneal concentrations of these ions do not depend on serum concentrations. Normal range of Ca2+ concentration in PF is 0.9-1.28 mmol/liter, that of Mg2+ 0.4-0.57 mmol/liter. In genital diseases the concentrations of Mg2+ are changed in 78.8% cases and those of Ca2+ in 45.8% cases.

[Aerosol pollution of sealed manned quarters]. / Aérozol'nye zagriaznenie obitaemykh germetichnykh pomeshchenii.

The paper discusses the man's contribution to the formation of aerosol particles in manned enclosures. The data obtained in prolonged simulation studies suggest that man is the major source of aerosol contamination. The aerosol concentration and disperse composition are found to depend on the free volume per man. The paper presents for the first time the data on the rate of dust formation in manned enclosures.