[Hypoxemia 4 month after right-sided pneumonectomy]. / Hypoxämie 4 Monate nach rechtsseitiger Pneumektomie.

A 64-year-old male reported worsening dyspnea four months after right-sided pneumonectomy, due to lung cancer. Platypneu-or-thodeoxie syndrome was suspected due to a decrease in oxygen-saturation while the patient was in upright position. The shift of the right hemidiaphragm and liver caused compression of the right atrium and a shunt over a persistent foramen ovale. The right-to-left shunt was proven during right heart catheter. Interventional closure of the shunt resulted in immediate improvement of arterial oxygenation and a decrease in dyspnea.

[Regular tachycardia with broad QRS complex: differential diagnosis on 12-lead ECG]. / Regelmässige Tachykardien mit breitem Kammerkomplex: Differenzialdiagnose mittels 12-Kanal-EKG.

Differential diagnosis of regular tachycardia with broad QRS complex can be challenging in daily practice. There are four different arrhythmias that have to be taken into account when being confronted with a broad QRS complex tachycardia: (1) ventricular tachycardia (VT); (2) supraventricular tachycardia (SVT) with bundle branch block (BBB); (3) SVT with AV conduction over an accessory AV pathway; (4) paced ventricular rhythm. Due to potentially fatal consequences, the correct diagnosis is important in view of both the acute treatment and the long-term therapy. Since SVT with accessory conduction is rare and a paced ventricular rhythm can be identified easily by stimulation artifacts, in most cases, a VT has to be differentiated from an SVT with BBB. Several ECG criteria can be helpful: (1) QRS complex duration > 140 ms in right BBB tachycardia or > 160 ms in left BBB tachycardia; (2) ventricular fusion beats; (3)"Northwest" QRS axis; (4) ventriculoatrial dissociation; (5) absence of an RS complex or RS interval > 100 ms in leads V(1)-V(6); (6) a positive or negative concordant R wave progression pattern in leads V(1)-V(6); (7) absence of an initial R wave or an S wave in lead V(1) in right BBB tachycardia; (8) absence of an R wave or an R/S ratio < 1 in lead V(6) in right BBB tachycardia; (9) absence or delay of the initial negative forces in lead V(1) in left BBB pattern (R wave duration > 30 ms in V(1); interval between onset of R wave and Nadir of S wave > 60 ms in V(1)); (10) presence of Q wave. Any of these variables favor VT. However, none of the criteria has both a sufficient sensitivity and specificity when utilized on its own. Therefore, various diagnostic algorithms have been proposed using a number of the above criteria consecutively. By doing so, the specificity and sensitivity of correctly identifying a VT or an SVT with BBB can be raised to > 95%.