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2.
Bull Cancer ; 110(6): 616-622, 2023 Jun.
Artículo en Francés | MEDLINE | ID: mdl-37055308

RESUMEN

INTRODUCTION: Due to longer life expectancy, an increasing number of older people are at risk of developing cancer. Surgical resection of a non-metastatic and resectable digestive tumor remains the main therapeutic weapon. The objective of our study is to assess the possibility of curative oncological surgery in patients over 80years of age, to study its impact in terms of morbidity and mortality, and to look for risk factors for the occurrence of complications. PATIENTS AND METHODS: The study-included patients aged 80 and over operated on for digestive cancer in a curative situation. This was a multicenter prospective cohort study. A total of 230 patients were included in the study. In addition to demographic and medical data, the patients all benefited from an onco-geriatric assessment with the performance of various tests: WHO score, G8 score, IADL score, ADL score, mobility score, nutritional assessment, clock, thymic evaluation (Mini-GDS). Data collection of geriatric scores was repeated 3months postoperatively. RESULTS: Of a total of 230 patients, 51% were male and 49% female. The average age was 84.7years. Tumor localization was mainly colorectal (65.81%). Age had no influence on the mortality rate, with a mean age with no significant difference in the event of an unfavorable outcome or not (84.6 vs. 85years). The results at the different scores were then analyzed in search of a significant difference between preoperative and at 3months. The only significant difference found was in the number of patients with a WHO status of 0 (P=0.021). CONCLUSION: Our study shows that curative oncological surgery is possible in elderly patients without any adverse effect on their quality of life and level of postoperative autonomy. The multidisciplinary geriatric approach to the patient must make it possible to distinguish the patients who will benefit from a curative treatment and those in whom the benefit-risk balance is unfavorable.


Asunto(s)
Neoplasias del Sistema Digestivo , Calidad de Vida , Anciano , Humanos , Masculino , Femenino , Anciano de 80 o más Años , Estudios Prospectivos , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/epidemiología , Medición de Riesgo , Evaluación Geriátrica/métodos
3.
ANZ J Surg ; 93(5): 1355-1356, 2023 05.
Artículo en Inglés | MEDLINE | ID: mdl-36629384

RESUMEN

Transthoracic subtotal esophagectomy with two-field lymph node (mediastinal and abdominal) and monobloc posterior mediastinectomy is called Ivor Lewis esophagectomy. This intervention requires an abdominal and thoracic time that is carried out here entirely by robotic way. It is performed a reconstruction by gastroplasty with a manual esophago-gastric anastomosis also by robotic way.


Asunto(s)
Neoplasias Esofágicas , Procedimientos Quirúrgicos Robotizados , Robótica , Humanos , Esofagectomía , Neoplasias Esofágicas/cirugía , Neoplasias Esofágicas/patología , Ganglios Linfáticos/patología , Anastomosis Quirúrgica , Estudios Retrospectivos
4.
Radiology ; 305(1): 28-29, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-35699575

RESUMEN

Online supplemental material is available for this article.


Asunto(s)
Desplazamiento del Disco Intervertebral , Humanos , Vértebras Lumbares
6.
Clin Res Hepatol Gastroenterol ; 46(3): 101857, 2022 03.
Artículo en Inglés | MEDLINE | ID: mdl-34963649

RESUMEN

INTRODUCTION: Digestive cancer is of concern because of its frequency and severity with an increasing older median age of onset. The purpose of this study was to describe in a well-defined population presenting with non-metastatic digestive cancer the frequency of surgical resection and outcomes according to age. PATIENTS AND METHODS: We analyzed 7760 patients with a non-metastatic digestive cancer, recorded in the Burgundy population-based digestive cancer registry between 2009 and 2017. There were 3506 non-colorectal cancers and 4254 colorectal cancers with 3292 colon and 962 rectal cancers. The frequency of surgical resection was analyzed according to age (classified into four categories <70, [70-80[, [80-85[, and ≥85), sex, comorbidities and obesity. Postoperative mortality at 30 and 90 days was determined according to age, sex, comorbidity, obesity, location, surgery R0 or not. The 5-year survival study included 2952 patients with colorectal cancer, non-metastatic and who benefited from an R0 resection. RESULTS: Overall, 64% of the patients with M0 digestive cancer underwent a surgical resection, varying from 31% for Non colorectal Digestive cancers to 94% for colon site. The percentage of patients operated on for a resectable disease decreases from 71% before age 70 to 43% from age 85. Age and comorbidities were the main criteria influencing the probability of resection. At 30 days, postoperative mortality was 3%, all localizations and ages combined. At 90 days, this rate was 5%. In patients over 85 years old it gradually increases from 7% at 30 days and to 10% at 90 days. A man under 70 years of age has a net survival of 0.88 at 5 years, and 0.91 for a woman. For a man between 70 and 80 years old, it decreases to 0.81 and to 0.66 from 80 years old. In women, net survival is 0.87 between 70 and 80 years of age at 5 years, then drops to 0.75 from age 80. CONCLUSION: Our study shows a drop in access to surgery at different pivotal ages depending on the tumor location. This sudden drop in the resection rate is not justified by the increase in mortality with age, which is linear. In addition, the expected benefits of surgery are significant, with a net survival, mainly after the 1st year, of the same order as for younger patients. Age by itself should not be the only criterion in the medical decision. The challenge is to detect and treat the comorbidities that worsen the operative risk and the prognosis. There are few data on the management of digestive cancers specifically in the elderly. Our study shows that access to surgery is strongly linked to age and this in a non-linear way, whereas the expected benefits of surgery are significant, of the same order as for younger patients. Age itself should not be the only criterion in the medical decision.


Asunto(s)
Neoplasias Colorrectales , Neoplasias del Recto , Anciano , Anciano de 80 o más Años , Preescolar , Colon/patología , Neoplasias Colorrectales/patología , Comorbilidad , Femenino , Humanos , Masculino , Obesidad , Pronóstico
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