Pump-probe experiments at X-ray free-electron laser (XFEL) facilities are a powerful tool for studying dynamics at ultrafast and longer timescales. Observing the dynamics in diverse scientific cases requires optical laser systems with a wide range of wavelength, flexible pulse sequences and different pulse durations, especially in the pump source. Here, the pump-probe instrumentation available for measurements at the Single Particles, Clusters, and Biomolecules and Serial Femtosecond Crystallography (SPB/SFX) instrument of the European XFEL is reported. The temporal and spatial stability of this instrumentation is also presented.
Lasers , Crystallography, X-Ray , Radiography , X-Rays
Intense, ultrashort, and high-repetition-rate X-ray pulses, combined with a femtosecond optical laser, allow pump-probe experiments with fast data acquisition and femtosecond time resolution. However, the relative timing of the X-ray pulses and the optical laser pulses can be controlled only to a level of the intrinsic error of the instrument which, without characterization, limits the time resolution of experiments. This limitation inevitably calls for a precise determination of the relative arrival time, which can be used after measurement for sorting and tagging the experimental data to a much finer resolution than it can be controlled to. The observed root-mean-square timing jitter between the X-ray and the optical laser at the SPB/SFX instrument at European XFEL was 308 fs. This first measurement of timing jitter at the European XFEL provides an important step in realizing ultrafast experiments at this novel X-ray source. A method for determining the change in the complex refractive index of samples is also presented.
We provide a detailed description of a serial femtosecond crystallography (SFX) dataset collected at the European X-ray free-electron laser facility (EuXFEL). The EuXFEL is the first high repetition rate XFEL delivering MHz X-ray pulse trains at 10 Hz. The short spacing (<1 µs) between pulses requires fast flowing microjets for sample injection and high frame rate detectors. A data set was recorded of a microcrystalline mixture of at least three different jack bean proteins (urease, concanavalin A, concanavalin B). A one megapixel Adaptive Gain Integrating Pixel Detector (AGIPD) was used which has not only a high frame rate but also a large dynamic range. This dataset is publicly available through the Coherent X-ray Imaging Data Bank (CXIDB) as a resource for algorithm development and for data analysis training for prospective XFEL users.
Concanavalin A/chemistry , Plant Proteins/chemistry , Urease/chemistry , Crystallization , Crystallography, X-Ray
User operation at the European X-ray Free-Electron Laser Facility started at the SASE1 undulator beamline in fall 2017. The majority of the experiments utilize optical lasers (mostly ultrafast) for pump-probe-type measurements in combination with X-ray pulses. This manuscript describes the purpose-developed pump-probe laser system as installed at SASE1, implemented features and plans for further upgrades.
X-ray free-electron lasers (XFELs) enable novel experiments because of their high peak brilliance and femtosecond pulse duration. However, non-superconducting XFELs offer repetition rates of only 10-120 Hz, placing significant demands on beam time and sample consumption. We describe serial femtosecond crystallography experiments performed at the European XFEL, the first MHz repetition rate XFEL, delivering 1.128 MHz X-ray pulse trains at 10 Hz. Given the short spacing between pulses, damage caused by shock waves launched by one XFEL pulse on sample probed by subsequent pulses is a concern. To investigate this issue, we collected data from lysozyme microcrystals, exposed to a ~15 µm XFEL beam. Under these conditions, data quality is independent of whether the first or subsequent pulses of the train were used for data collection. We also analyzed a mixture of microcrystals of jack bean proteins, from which the structure of native, magnesium-containing concanavalin A was determined.
We report on substantial pulse energy increase in Yb:KYW femtosecond laser oscillators by utilizing multiple laser crystals for an enhanced net-gain at higher pump power. The two-crystal oscillator generates pulse energies of 7 µJ at 1 MHz repetition rate which is, to our knowledge the highest energy ever reported from an Yb-doped tungstate fs-laser oscillator. The external pulse compression yields a pulse duration of 416 fs with a peak power of 12 MW being enough for stable white light generation in YAG.
Lasers , Optics and Photonics , Oscillometry/instrumentation , Signal Processing, Computer-Assisted/instrumentation , Ytterbium/chemistry , Amplifiers, Electronic , Crystallization , Equipment Design , Light , Time Factors , Tungsten/chemistry
We demonstrate, what is to our knowledge the first passively mode-locked Ytterbium based solid state high energy laser oscillator operated in the positive dispersion regime. Compared to solitary mode-locking the pulse energy can be increased with even broader spectral bandwidth. With high speed cavity dumping the laser generates 2 muJ-pulses at a 1 MHz repetition rate. The chirped output pulses are compressible down to 420 fs.
Ultrahigh resolution optical coherence tomography (OCT) is demonstrated at 800 nm and 1300 nm using continuum generation in a single photonic crystal fiber with a parabolic dispersion profile and two closely spaced zero dispersion wavelengths. Both wavelengths are generated simultaneously by pumping the fiber with ~78 mW average power at 1064 nm in a 52 MHz, 85 fs pulse train from a compact Nd:Glass oscillator. Continuum processes result in a double peak spectrum with > 110 nm and 30 mW average power at 800 nm and > 150 nm and 48 mW at 1300 nm. OCT imaging with < 5 mum resolution in tissue at 1300 nm and < 3 mum resolution at 800 nm is demonstrated. Numerical modeling of propagation was used to predict the spectrum and can be used for further optimization to generate smooth, broad spectra for OCT applications.
We report generation of 1.35 microJ femtosecond laser pulses with a peak power of 3 MW at 1 MHz repetition rate from a diode-pumped Yb:KY(WO4)2 laser oscillator with cavity dumping. By extracavity compression with a large-mode-area fiber and a prism sequence, we generate ultrashort pulses with a duration of 21 fs and a peak power of 13 MW.
We present a compact, all diode-pumped supercontinuum source based on a SESAM mode-locked Yb:glass oscillator at 1040 nm and a tapered fiber. The oscillator has a repetition rate of 20 MHz, a pulse duration of 200 fs, and a maximum pulse energy of about 15 nJ. This system delivers an 1100 nm broad spectrum with an output power of more than 100 mW. Decreasing the repetition rate to 500 kHz by cavity-dumping results in a supercontinuum with a high pulse energy of about 50 nJ. Furthermore, using the frequency-doubled output of this laser at 520 nm with 300 fs pulse duration resulted in supercontinua in the near-UV and visible spectral region. We compare the experimental spectra with theoretical simulations.
High speed electro-optical cavity dumping is demonstrated with diode-pumped mode-locked laser oscillators, namely a femtosecond Yb:glass and a picosecond Nd:YVO4 oscillator. Repetition frequencies exceeding 1MHz are obtained with pulse energies of more than 300nJ /1 microJ. Being compact and easy to operate light sources, these laser systems open up various scientific and industrial applications.
We investigate the modelocking dynamics of quasi-synchronously pumped, dispersion managed Kerr-lens modelocked Titanium-Sapphire lasers. For the first time, self-starting few-cycle laser pulses with 6 fs pulse duration and ultrabroadband optical spectra are demonstrated without using any intracavity elements like saturable absorbers.
Laser action is demonstrated in a 20-mm-long waveguide fabricated on an Er:Yb-doped phosphate glass by femtosecond laser pulses. An output power of 1.7 mW with approximately 300 mW of pump power coupled into the waveguide is obtained at 1533.5 nm. Waveguides are manufactured with the 520-nm radiation from a frequency-doubled, diode-pumped, cavity-dumped Yb:glass laser operating at a 166-KHz repetition rate, with a 300-fs pulse duration.
Optical waveguide writing is demonstrated by means of a diode-pumped cavity-dumped Yb:glass femtosecond laser oscillator with a pulse energy of 270 nJ at a 166-kHz repetition rate. Waveguides realized on an Er:Yb-doped phosphate glass are almost perfectly mode matched to standard single-mode fibers at 1.55 microm and show a 1.2-dB net gain in a standard telecommunications amplifier setup. Waveguide writing with a compact femtosecond laser oscillator is an important step toward introducing this technique into an industrial context.
Multi-energy and chaotic pulse energy output from a continuously pumped regenerative amplifier is observed for dumping rates around the inverse upper state lifetime of the gain medium. The relevant regimes of operation are analyzed numerically and experimentally in a diode-pumped Yb:glass regenerative amplifier. The boundaries between stable and unstable pulsing are identified and stability criteria in dependence on the amplifier gate length and pump power are discussed.
