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1.
Int. braz. j. urol ; 47(1): 149-158, Jan.-Feb. 2021. tab, graf
Artículo en Inglés | LILACS | ID: biblio-1134310

RESUMEN

ABSTRACT Purpose: Renal artery pseudoaneurysms (RAPs) and arteriovenous fistulas (AVFs) are rare but potentially life-threatening complications after partial nephrectomy (PN). Selective arterial embolization (SAE) is an effective method for controlling RAPs/AVFs. We assessed the clinical factors affecting the occurrence of RAPs/AVFs after PN and the effects of SAE on postsurgical renal function. Materials and Methods: Four hundred ninety-three patients who underwent PN were retrospectively reviewed. They were placed in either the SAE or the non-SAE group. The effects of clinical factors, including R.E.N.A.L. scores, on the occurrence of RAPs/AVFs were analyzed. The influence of SAE on the estimated glomerular filtration rate (eGFR) during the first postoperative year was evaluated. Results: Thirty-three (6.7%) patients experienced RAPs/AVFs within 8 days of the median interval between PN and SAE. The SAE group had significantly higher R.E.N.A.L. scores, higher N component scores, and higher L component scores (all, p <0.05). In the multivariate analysis, higher N component scores were associated with the occurrence of RAPs/AVFs (Odds ratio: 1.96, p=0.039). In the SAE group, the mean 3-day postembolization eGFR was significantly lower than the mean 3-day postoperative eGFR (p <0.01). This difference in the eGFRs was still present 1 year later. Conclusions: Renal tumors located near the renal sinus and collecting system were associated with a higher risk for RAPs/AVFs after PN. Although SAE was an effective method for controlling symptomatic RAPs/AVFs after PN, a procedure-related impairment of renal function after SAE could occur and still be present at the end of the first postoperative year.


Asunto(s)
Humanos , Fístula Arteriovenosa/etiología , Aneurisma Falso/etiología , Neoplasias Renales/cirugía , Estudios Retrospectivos , Resultado del Tratamiento , Tasa de Filtración Glomerular , Nefrectomía/efectos adversos
2.
Int Braz J Urol ; 47(1): 149-158, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33047920

RESUMEN

PURPOSE: Renal artery pseudoaneurysms (RAPs) and arteriovenous fistulas (AVFs) are rare but potentially life-threatening complications after partial nephrectomy (PN). Selective arterial embolization (SAE) is an effective method for controlling RAPs/AVFs. We assessed the clinical factors affecting the occurrence of RAPs/AVFs after PN and the effects of SAE on postsurgical renal function. MATERIALS AND METHODS: Four hundred ninety-three patients who underwent PN were retrospectively reviewed. They were placed in either the SAE or the non-SAE group. The effects of clinical factors, including R.E.N.A.L. scores, on the occurrence of RAPs/AVFs were analyzed. The influence of SAE on the estimated glomerular filtration rate (eGFR) during the first postoperative year was evaluated. RESULTS: Thirty-three (6.7%) patients experienced RAPs/AVFs within 8 days of the median interval between PN and SAE. The SAE group had significantly higher R.E.N.A.L. scores, higher N component scores, and higher L component scores (all, p <0.05). In the multivariate analysis, higher N component scores were associated with the occurrence of RAPs/AVFs (Odds ratio: 1.96, p=0.039). In the SAE group, the mean 3-day postembolization eGFR was significantly lower than the mean 3-day postoperative eGFR (p <0.01). This difference in the eGFRs was still present 1 year later. CONCLUSIONS: Renal tumors located near the renal sinus and collecting system were associated with a higher risk for RAPs/AVFs after PN. Although SAE was an effective method for controlling symptomatic RAPs/AVFs after PN, a procedure-related impairment of renal function after SAE could occur and still be present at the end of the first postoperative year.


Asunto(s)
Aneurisma Falso , Fístula Arteriovenosa , Neoplasias Renales , Aneurisma Falso/etiología , Fístula Arteriovenosa/etiología , Tasa de Filtración Glomerular , Humanos , Neoplasias Renales/cirugía , Nefrectomía/efectos adversos , Estudios Retrospectivos , Resultado del Tratamiento
3.
Artículo en Inglés | MEDLINE | ID: mdl-15829891

RESUMEN

OBJECTIVE: This study intended to compare the prevalence of 7 putative endodontic pathogens in samples of primary endodontic infections taken from patients of 2 distant geographic locations. STUDY DESIGN: Samples from infected root canals associated with asymptomatic periradicular lesions or from pus aspirated from acute periradicular abscesses were collected from patients in Rio de Janeiro, Brazil, and Seoul, South Korea. South Korean samples were frozen and delivered to Brazil, where all steps in the molecular analysis were performed. DNA was extracted and a species-specific nested polymerase chain reaction assay was used to detect 7 target bacterial species. RESULTS: The most prevalent species detected in Brazilian samples were Porphyromonas endodontalis (79% of the cases) , Treponema denticola (79%), and Dialister pneumosintes (76%). The most prevalent species found in South Korean samples were Fusobacterium nucleatum (38% of the cases) , Tannerella forsythia (26%), and Treponema maltophilum (24%). Overall, P endodontalis, D pneumosintes, Filifactor alocis, T denticola, and T forsythia were significantly more detected in Brazilian samples than in South Korean samples ( P < .05). CONCLUSIONS: Findings indicated that the prevalence of some species in infections of endodontic origin may significantly differ from one geographic location to another.


Asunto(s)
Periodontitis Periapical/microbiología , Adolescente , Adulto , Anciano , Técnicas de Tipificación Bacteriana , Bacteroides/aislamiento & purificación , Brasil , Distribución de Chi-Cuadrado , ADN Bacteriano/análisis , Fusobacterium/aislamiento & purificación , Bacilos Gramnegativos Anaerobios Rectos, Curvos y Espirales/aislamiento & purificación , Humanos , Corea (Geográfico) , Persona de Mediana Edad , Epidemiología Molecular , Reacción en Cadena de la Polimerasa/métodos , Porphyromonas endodontalis/aislamiento & purificación , Treponema/aislamiento & purificación
4.
J Endod ; 30(7): 504-8, 2004 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-15220647

RESUMEN

A large body of evidence indicates that microorganisms are the primary causative agents of endodontic treatment failures. This study intended to assess the occurrence of nine putative endodontic pathogens in root-filled teeth associated with periradicular lesions in a South Korean population using a culture-independent molecular approach. Fourteen root-filled teeth with persistent periradicular diseases were selected for retreatment. After removal of the root canal filling, the canals were sampled, and a polymerase chain reaction assay using taxon-specific oligonucleotide primers was used for microbial detection. Bacteria were present in all cases, as revealed by amplification using ubiquitous 16S rDNA primers. The most frequently detected taxon was Enterococcus faecalis (64%), followed by Streptococcus spp. (21%) and Tannerella forsythensis (14%). The results of this study using a highly sensitive identification method are concurrent with those from other geographical locations using diverse identification methods in that E. faecalis is the main species found in cases of root-filled teeth associated with periradicular lesions.


Asunto(s)
Bacterias/clasificación , Cavidad Pulpar/microbiología , Tratamiento del Conducto Radicular , Adolescente , Adulto , Anciano , Bacteroides/aislamiento & purificación , Infecciones por Bacteroides/microbiología , Cartilla de ADN , Enterococcus faecalis/aislamiento & purificación , Femenino , Infecciones por Bacterias Grampositivas/microbiología , Humanos , Corea (Geográfico) , Masculino , Persona de Mediana Edad , Enfermedades Periapicales/microbiología , Reacción en Cadena de la Polimerasa , ARN Bacteriano/análisis , ARN Ribosómico 16S/análisis , Infecciones Estreptocócicas/microbiología , Streptococcus/clasificación , Insuficiencia del Tratamiento
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