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1.
Sci Rep ; 14(1): 1309, 2024 Jan 15.
Artículo en Inglés | MEDLINE | ID: mdl-38225266

RESUMEN

The field monitoring data showed that a small amount of main reinforcement bars of lattice girder at the arch of a tunnel were pulled, and the calculation showed that the initial support structure should be compressed. To find out the reason for the tension of the main reinforcement, the geological radar was used to detect the cavity in the sprayed concrete layer at the tension position. In order to clarify the tension mechanism of the main reinforcement and the influence of factors such as the position and size of the cavity on the main reinforcement, numerical simulations were carried out. The results show that the cavity causes the eccentric compression of the shotcrete layer, resulting in moment of the lattice girder and the change of the stress distribution of the main reinforcement. The main reinforcement experiences tensile stress when the cavity size surpasses 3 m × 0.2 m, reaching a tensile stress of 81 MPa at a cavity size of 6 m × 0.2 m. Notably, the cavity located at the foot of the arch is more likely to produce substantial tensile stress on the primary reinforcement compared to those at the arch crown and waist. The research results provide a theoretical basis for the interpretation and analysis of tunnel lattice girder monitoring data.

2.
Neuropediatrics ; 54(3): 167-173, 2023 06.
Artículo en Inglés | MEDLINE | ID: mdl-36827993

RESUMEN

AIM: This study aimed to evaluate the effectiveness of melatonin in treating insomnia in children with autism spectrum disorder (ASD). METHODS: Comprehensive searches were conducted in the PubMed, EMBASE, and Web of Science databases from their inception to April 20, 2022. Data were extracted and assessed for quality by two researchers. Statistical analysis was performed using the Stata 15.0 software. RESULTS: Four studies including 238 patients were included. The results showed that compared with the control group, melatonin could shorten the sleep-onset latency (standardized mean difference [SMD] = - 1.34, 95% CI: -2.19 to -0.48), reduce the number of awakenings (SMD = -2.35, 95% CI: -4.62 to -0.08), and prolong the total sleep time (SMD = 1.42, 95% CI: 0.5-2.33) in children with ASD. CONCLUSION: Melatonin has a certain effect on relieving sleep disturbances in children with ASD, which can shorten sleep latency, reduce the number of awakenings, and prolong total sleep time. Larger studies are required to verify this hypothesis.


Asunto(s)
Trastorno del Espectro Autista , Melatonina , Trastornos del Inicio y del Mantenimiento del Sueño , Trastornos del Sueño-Vigilia , Humanos , Niño , Melatonina/uso terapéutico , Trastorno del Espectro Autista/complicaciones , Trastorno del Espectro Autista/tratamiento farmacológico , Trastornos del Inicio y del Mantenimiento del Sueño/complicaciones , Trastornos del Inicio y del Mantenimiento del Sueño/tratamiento farmacológico , Duración del Sueño
3.
Sci Rep ; 12(1): 7918, 2022 May 13.
Artículo en Inglés | MEDLINE | ID: mdl-35562394

RESUMEN

Considering the large-span underground excavation subway station of Qingdao Metro Line 6 of China for analysis, it is necessary to optimize the traditional support system by investigating relevant codes and other tunnel projects. Based on the active support concept, a high prestressed rock bolt support system is proposed, and the optimization direction is defined to apply a high prestress force to rock bolts, increasing the appropriate spacing between supporting arches and strengthening support at key parts such as the large arch foot area, sidewalls and junctions. Numerical calculations and field monitoring are performed to analyze and evaluate the new support system. Numerical simulation results show that the new support system can effectively improve the stress state of the surrounding rock; the tensile stress area markedly decreases in size or disappears; and the plastic area also decreases in size. Field monitoring results show that the settlement of the arch crown is concentrated at 2-5 mm and the deformation rates are less than 0.5 mm/day. The supporting arches, shotcrete and rock bolts are all less than the yield strength and a high safety reserve. These results verify the safety and rationality of the proposed support system, which can be used as a reference for similar projects.

4.
J Healthc Eng ; 2020: 5379593, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32076495

RESUMEN

Background: A large number of pelvic injuries are seriously unstable, with mortality rates reaching 19%. Approximately 60% of pelvic injuries are related to the posterior pelvic ring. However, the selection of a fixation method for a posterior pelvic ring injury remains a challenging problem for orthopedic surgeons. The aim of the present study is to investigate the biomechanical performance of five different fixation approaches for posterior pelvic ring injury and thus provide guidance on the choice of treatment approach in a clinical setting. Methods: A finite element (FE) model, including the L3-L5 lumbar vertebrae, sacrum, and full pelvis, was created from CT images of a healthy adult. Tile B and Tile C types of pelvic fractures were created in the model. Five different fixation methods for fixing the posterior ring injury (PRI) were simulated: TA1 (conservative treatment), TA2 (S1 screw fixation), TA3 (S1 + S2 screw fixation), TA4 (plate fixation), and TA5 (modified triangular osteosynthesis). Based on the fixation status (fixed or nonfixed) of the anterior ring and the fixation method for PRI, 20 different FE models were created. An upright standing loading scenario was simulated, and the resultant displacements at the sacroiliac joint were compared between different models. Results: When TA5 was applied, the resultant displacements at the sacroiliac joint were the smallest (1.5 mm, 1.6 mm, 1.6 mm, and 1.7 mm) for all the injury cases. The displacements induced by TA3 and TA2 were similar to those induced by TA5. TA4 led to larger displacements at the sacroiliac joint (2.3 mm, 2.4 mm, 4.8 mm, and 4.9 mm), and TA1 was the worst case (3.1 mm, 3.2 mm, 6.3 mm, and 6.5 mm). Conclusions: The best internal fixation method for PRI is the triangular osteosynthesis approach (TA5), followed by S1 + S2 screw fixation (TA3), S1 screw fixation (TA2), and plate fixation (TA4).


Asunto(s)
Fenómenos Biomecánicos , Fracturas Óseas/cirugía , Huesos Pélvicos/lesiones , Procedimientos Quirúrgicos Operativos/métodos , Adulto , Placas Óseas , Análisis de Elementos Finitos , Fijación Interna de Fracturas/métodos , Humanos , Masculino
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