Synthesis of Polymeric Janus Superstructures via a Facile Synthesis Method.

Polymeric Janus particles can be exploited for a myriad of applications. Through the understanding of interfacial tensions, theragnostic agents such as drugs or nanomaterials can be successfully encapsulated into Janus particles without losing their anisotropic structure. In this work, it is reported that how Janus superstructures, as a further extension of the Janus morphology, can be obtained by blending other synthesis parameters into the solvent emulsion process, while adhering to the requirements of the Harkin's spreading coefficient (HSC) theory. Designing such unique structures for drug delivery can provide a broader range of possibilities and applications beyond conventional Janus particles.

Hybrid Janus Microparticles Achieving Selective Encapsulation for Theranostic Applications via a Facile Solvent Emulsion Method.

Anisotropic Janus particles composed of biocompatible polymers have been gaining considerable interest for biomedical applications. Here, the fabrication of hybrid Janus particles via a single-step solvent emulsion technique, potentially for theranostic purposes, is shown. Through this technique, the selective encapsulation of therapeutic and diagnostic agents is streamlined into different "faces" of the Janus structure. This facile technique is used to seamlessly fabricate polymeric-based hybrid Janus particles for theranostic applications with little complexity.