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1.
Best Pract Res Clin Obstet Gynaecol ; 97: 102550, 2024 Sep 03.
Artículo en Inglés | MEDLINE | ID: mdl-39243521

RESUMEN

The World Health Organization includes oral emergency contraception (EC) in the list of essential medicines. Ulipristal acetate (UPA) and levonorgestrel (LNG) are the recommended oral methods. UPA has superior efficacy and a comparable side effect profile compared with LNG. Both work by inhibiting or delaying ovulation, so that sperm present in the reproductive tract will have lost their fertilising ability by the time the oocyte is eventually released. Neither LNG nor UPA at the EC doses have significant effects on the endometrium and are unable to prevent implantation. Mifepristone can also be used for EC but its availability is limited to few countries. LNG is less effective in women with a body mass index over 26 kg/m2 or weight over 70 kg. Hormonal contraception can be quickstarted immediately following LNG, or five days following UPA. LNG-releasing intrauterine devices and cyclo-oxygenase inhibitors are promising options for EC to be further studied.

2.
Artículo en Inglés | MEDLINE | ID: mdl-39271236

RESUMEN

OBJECTIVES: To revisit women's knowledge, attitudes and practices (KAP) regarding emergency contraception (EC) in Hong Kong. The research sought to provide insights for improving the accessibility and quality of EC services. STUDY DESIGN: A cross-sectional study, where self-administered questionnaires were distributed at a major community sexual and reproductive health service in Hong Kong over a 3-month period between July 2023 and October 2023. Descriptive and regression analyses were used. RESULTS: Of 1127 respondents, the majority (n=1057, 93.8%) reported using contraception and 513 (45.6%) had used EC. The main contraceptive methods used were male condoms and oral contraceptive pills. The majority (n=1035, 91.8%) of respondents demonstrated awareness about EC and 938 (83.2%) participants correctly reported the timeframe for oral EC. Around two-thirds reported the internet as being their leading source of EC knowledge. Over 93% of respondents advocated for enhancing public awareness. Acceptance of non-traditional means of obtaining EC, such as over-the-counter provision (51.3%), pharmacy provision (49.8%) and telemedicine consultation (43.1%), were higher than face-to-face EC consultations (32.9%). CONCLUSIONS: Family planning service users' characteristics and KAP regarding EC have significantly changed over the last 20 years. Women now demonstrate greater awareness, knowledge and openness regarding EC, indicating improved readiness for more liberal delivery of EC nowadays. This study highlights the need for restructuring EC service provision in Hong Kong to address women's changing preferences and contraceptive needs, and to minimise barriers to EC access. We recommend reclassifying emergency contraceptive pills as non-prescription drugs in Hong Kong to align with international practice.

4.
Lancet ; 402(10405): 851-858, 2023 09 09.
Artículo en Inglés | MEDLINE | ID: mdl-37597523

RESUMEN

BACKGROUND: Levonorgestrel, a standard drug for emergency contraception (EC), is not effective if administered post-ovulation. A cyclo-oxygenase inhibitor could contribute synergistic effects. We investigated whether a single 40 mg oral dose of piroxicam as co-treatment with levonorgestrel improved emergency contraceptive efficacy. METHODS: This was a randomised double-blind placebo-controlled trial carried out in a major community sexual and reproductive health service in Hong Kong. Women who required levonorgestrel EC within 72 h of unprotected sexual intercourse were recruited and block-randomised in a 1:1 ratio to receive a single supervised dose of levonorgestrel 1·5 mg plus either piroxicam 40 mg or placebo orally. Group assignment was concealed in opaque envelopes and masked to the women, clinicians, and investigators. At follow-up 1-2 weeks after the next expected period, the pregnancy status was noted by history or pregnancy test. The primary efficacy outcome was the proportion of pregnancies prevented out of those expected based on an established model. All women randomised to receive the study drug and who completed the follow-up were analysed. The trial was registered with ClinicalTrials.gov, NCT03614494. FINDINGS: 860 women (430 in each group) were recruited between Aug 20, 2018, and Aug 30, 2022. One (0·2%) of 418 efficacy-eligible women in the piroxicam group were pregnant, compared with seven (1·7%) of 418 in the placebo group (odds ratio 0·20 [95% CI 0·02-0·91]; p=0·036). Levonorgestrel plus piroxicam prevented 94·7% of expected pregnancies compared with 63·4% for levonorgestrel plus placebo. We noted no significant difference between the two groups in the proportion of women with advancement or delay of their next period, or in the adverse event profile. INTERPRETATION: Oral piroxicam 40 mg co-administered with levonorgestrel improved efficacy of EC in our study. Piroxicam co-administration could be considered clinically where levonorgestrel EC is the option of choice. FUNDING: None.


Asunto(s)
Anticoncepción Postcoital , Anticonceptivos Poscoito , Femenino , Embarazo , Humanos , Piroxicam , Levonorgestrel , Inhibidores de la Ciclooxigenasa
5.
J Sex Med ; 20(1): 30-37, 2023 01 14.
Artículo en Inglés | MEDLINE | ID: mdl-36897240

RESUMEN

BACKGROUND: Cross-sectional studies have shown that sexual dysfunction and poor quality of life were prevalent among couples undergoing assisted reproduction at specific time points, but nothing is known about how these outcomes change over the course of their intrauterine insemination (IUI) journey. AIM: We investigated the longitudinal changes in sexual function and quality of life of infertile couples undergoing IUI. METHODS: Sixty-six infertile couples completed an anonymous questionnaire at 3 time points: after IUI counseling (T1), 1 day before IUI (T2), and 2 weeks after IUI (T3). The questionnaire consisted of demographic data, Female Sexual Function Index (FSFI) or International Index of Erectile Function-5, and Fertility Quality of Life (FertiQoL). OUTCOMES: Descriptive statistics, significance testing with the Friedman test, and post hoc analysis with the Wilcoxon signed rank test were used to compare changes in sexual function and quality of life at different time points. RESULTS: Overall, 18 (26.1%), 16 (23.2%), and 12 (17.4%) women and 29 (42.0%), 37 (53.6%), and 31 (44.9%) men were at risk for sexual dysfunction at T1, T2, and T3, respectively. There were significant differences in mean FSFI scores in arousal (3.87, 4.06, 4.10) and orgasm (4.15, 4.24, 4.39) domains at T1, T2, and T3. After post hoc analysis, only the increase in mean orgasm FSFI scores between T1 and T3 was statistically significant. Men's FertiQoL scores remained high during IUI (74.33-75.63 out of 100). Men also scored significantly higher than women on all FertiQoL domains except environment at the 3 time points. Post hoc analysis showed significant improvement in women's FertiQoL domain scores between T1 and T2: mind-body, environment, treatment, and total. Women's FertiQoL score at T2 for the treatment domain was also significantly higher than that at T3. CLINICAL IMPLICATIONS: Men should not be neglected during IUI as their erectile function got worse in the process, with half of the men being affected. Although women's quality of life showed some improvement during IUI, most of their scores were lower than men's. STRENGTHS AND LIMITATIONS: The use of psychometrically validated questionnaires and a longitudinal approach are the major strengths; a small sample size and the lack of a dyadic approach are the major limitations. CONCLUSION: During IUI, women's sexual performance and quality of life improved. The proportion of men having erectile problems was high for this age group, but men's FertiQoL scores remained good and were better than their partners' throughout IUI.


Asunto(s)
Disfunción Eréctil , Infertilidad , Disfunciones Sexuales Fisiológicas , Masculino , Humanos , Femenino , Estudios Longitudinales , Calidad de Vida/psicología , Estudios Transversales , Infertilidad/psicología , Encuestas y Cuestionarios , Inseminación
6.
Arch Osteoporos ; 17(1): 60, 2022 04 08.
Artículo en Inglés | MEDLINE | ID: mdl-35396655

RESUMEN

A total of 277 Hong Kong Chinese men participated in this prospective cohort study. Their osteoporosis knowledge was average. Their perceived susceptibility to osteoporosis was low. Barriers to lifestyle modifications were the strongest predictor for self-efficacy in adopting these activities. These results are useful for planning osteoporosis public awareness campaigns for men. PURPOSE: Male osteoporosis had long been neglected despite one-third of fractures occurring in men. Lifestyle modification through education is the main tactic in osteoporosis prevention, but current programs and strategies are designed for postmenopausal women. Understanding men's knowledge, health belief, and self-efficacy in adopting osteoporosis prevention strategies can help to design a specific program for men. METHODS: A prospective cohort study was conducted in three men's health clinics in Hong Kong from September to October 2020, recruiting 277 men aged ≥ 20 years. They completed a questionnaire consisting of sociodemographic data, 14 general questions from the Facts on Osteoporosis Quiz (FOOQ), Male Osteoporosis Knowledge Quiz (MOKQ), Osteoporosis Health Belief Scale (OHBS), and Osteoporosis Self-Efficacy Scale (OSES). Scores from these scales and their association with sociodemographic data were reported. Correlations between age, knowledge, health beliefs, and self-efficacy were studied using the Health Belief Model. RESULTS: The mean age was 36.4 years old, and 52% had university education. Their mean FOOQ + MOKQ score was 10.8 out of 20; mean OHBS score was 129.2 out of 210; and mean OSE-Exercise and OSE-Calcium scores were 66.4 and 68.9 out of 100 respectively. Self-efficacy of exercise was correlated with young age, perceived exercise benefits, and little barriers to exercise (p < 0.01). Self-efficacy of calcium intake was positively correlated with health motivation and self-efficacy of exercise and negatively correlated with barriers to calcium intake (p < 0.01). CONCLUSION: Male osteoporosis awareness programs should focus on improving knowledge, enhancing awareness on susceptibility, promoting benefits of lifestyle modification, and helping men overcome perceived barriers.


Asunto(s)
Osteoporosis , Autoeficacia , Adulto , Calcio , Femenino , Conocimientos, Actitudes y Práctica en Salud , Hong Kong , Humanos , Masculino , Osteoporosis/prevención & control , Estudios Prospectivos
7.
Hum Fertil (Camb) ; 25(3): 593-599, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-33432863

RESUMEN

Couples undergoing assisted reproductive technologies (ART) are prone to sexual dysfunction and lower quality of life (QoL), but whether the incidence of these problems differs with the type of ART is unknown. As such, we conducted this cross-sectional survey to compare the sexual function and QoL of 75 couples undergoing intrauterine insemination (IUI), and 160 couples undergoing in vitro fertilization (IVF). They completed an anonymous questionnaire which included: (i) demographic characteristics; (ii) female sexual function index (FSFI) or (iii) international index of erectile function-5 (IIEF-5); and (iv) fertility QoL questionnaire (FertiQoL). Overall, 22.6% of wives and 39.1% of husbands were at risk for sexual dysfunction, and the risk was similar in IUI and IVF groups. Mean core/treatment/total FertiQoL scores of husbands were higher than wives: 74.98 vs. 68.24/70.02 vs. 65.87/73.52 vs. 67.54 (all p < 0.001). FertiQoL scores were similar in IUI and IVF groups except wives' treatment FertiQoL score was significantly higher in the IUI group (68.93 vs. 64.44; p = 0.009). This study confirms that risks for sexual dysfunction were similar in IUI and IVF couples. Wives undergoing IVF had significantly lower treatment FertiQoL score. In both IUI and IVF groups, husbands' QoL was better than wives' QoL.


Asunto(s)
Fertilización In Vitro , Calidad de Vida , China , Estudios Transversales , Femenino , Humanos , Masculino , Estudios Prospectivos
8.
BMJ Sex Reprod Health ; 48(2): 117-122, 2022 04.
Artículo en Inglés | MEDLINE | ID: mdl-34725054

RESUMEN

BACKGROUND: The mechanism of action of a contraceptive method is an importantg consideration in a woman's choice of contraception. For the development of new methods of contraception it is important to understand the acceptability of different contraceptive mechanisms within a population. METHODS: We recruited women attending contraceptive, termination of pregnancy or postnatal care services in Hong Kong for a questionnaire survey on their acceptability of the different ways in which contraceptive methods prevent pregnancy. Univariable and multivariable analyses were used to establish factors which may predict acceptability of the mechanism of action. RESULTS: A total of 1448 women completed the survey. The acceptability of contraceptive methods that act by preventing fertilisation ranked highest (78%), followed by those that inhibit ovulation (52%), disrupt implantation (43%) and dislodge an implanted embryo (30%). A history of termination of pregnancy was associated with greater acceptance of all posited contraceptive mechanisms. There was a very low degree of agreement between the declared acceptance of the various contraceptive mechanisms and the ever use of a method with the respective mechanism of action (Cohen's kappa coefficient range 0.017-0.162). CONCLUSIONS: In this population the acceptability of contraceptive methods that act by preventing fertilisation ranked highest, followed by those that inhibit ovulation, disrupt implantation and dislodge an implanted embryo. Women who had ever had a termination of pregnancy were more likely to accept all the posited contraceptive mechanisms.


Asunto(s)
Anticoncepción , Anticonceptivos , Anticoncepción/métodos , Femenino , Hong Kong , Humanos , Embarazo , Encuestas y Cuestionarios
9.
J Sex Res ; 59(2): 203-211, 2022 02.
Artículo en Inglés | MEDLINE | ID: mdl-33528275

RESUMEN

Western studies have demonstrated that female sexual assertiveness is positively associated with sexual satisfaction in a committed heterosexual relationship. Furthermore, the ability of women to refuse sex has been shown to protect them from unwanted sexual contact and to lead to fewer sexual victimization experiences and less risky sexual behavior. However, there is little research on female sexual assertiveness that included both the own (actor effect) and partner (partner effect) impact of female sexual assertiveness on sexual satisfaction from a dyadic approach, involving both members of a couple. The data for the present study came from a representative sample of Chinese couples collected by the Hong Kong Family Planning Association in 2017. Using the actor-partner interdependence model, the results indicated that female sexual initiation was positively associated with both their own and their partner's sexual satisfaction. However, female sexual refusal was not associated with the sexual satisfaction of either party. These findings suggest the importance of adopting a dyadic approach in sex research to capture the mutual influences between partners. Couples should be encouraged to express their sexual desires and refuse unwanted sex requests honestly to improve their and their partner's sexual satisfaction.


Asunto(s)
Asertividad , Orgasmo , Femenino , Hong Kong , Humanos , Relaciones Interpersonales , Satisfacción Personal , Conducta Sexual , Parejas Sexuales
10.
Osteoporos Sarcopenia ; 7(3): 92-97, 2021 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-34632111

RESUMEN

OBJECTIVES: To determine the prevalence of osteoporosis and the proportion who needed treatment after screening women aged 65 years or older; their treatment acceptance and continuation. METHODS: This is an observational study conducted between May 2017 and April 2020.Participants underwent clinical assessment and bone mineral density measurement of lumbar spine, total hip, and femoral neck by dual energy X-ray absorptiometry. Those with osteoporosis at any site or osteopenia with 10-year major fracture risk ≥ 20% or hip fracture risk ≥ 3% by Fracture Risk Assessment Tool® were offered drug treatment. RESULTS: Among 1800 participants, 15.9% were normal, 33.2% were low-risk osteopenic, 27.2% were high-risk osteopenic, and 23.7% were osteoporotic. Their mean age was 69.4 years and 6.3% had low-energy fractures after menopause. After stepwise logistic regression analysis, only prior low-energy fractures after menopause and low body mass index (BMI) remained significantly correlated with osteoporosis. Those who needed treatment were significantly older, menopaused at age 45 years or earlier, had a parent with hip fracture, had low-energy fractures after menopause, and low BMI. Drug was offered to 916 women but 67.6% refused because they worried about side effects, interaction with existing drugs, and were reluctant to take more drugs. Treatment acceptance was significantly higher among osteoporotic patients. Treatment continuation at 6th and 12th months was also significantly higher in osteoporotic patients. CONCLUSIONS: Osteoporosis screening in elderly women identified a significant proportion who needed treatment. Encouraging them to initiate drug, especially high-risk osteopenic patients, remained a challenge.

11.
J Sex Med ; 15(11): 1620-1628, 2018 11.
Artículo en Inglés | MEDLINE | ID: mdl-30415814

RESUMEN

INTRODUCTION: Research conducted in the West has shown that sexual function and distress was common in white women from younger to older adulthood; however, little research attention to date has been given to Chinese young women. AIM: Our primary aim is to assess the prevalence and factors associated with sexual problems and distress in Chinese unmarried young women. METHODS: Between November 2015 and June 2017, 431 young women who visited 3 sexual health clinics completed an anonymous questionnaire detailing their demographics, sexual behavior, current sexual relationship, sexual function, and sexual distress. Descriptive bivariate analysis and logistic regression analyses were performed. MAIN OUTCOME MEASURES: Sexual function and distress were assessed by the Female Sexual Function Index (FSFI) and Female Sexual Distress Scale-Revised (FSDS-R), respectively. RESULTS: Overall, 76 young women (17.6%) obtained total FSFI score ≤23.45 (Chinese cut-off), 47 of whom scored 11 or above for FSDS-R. Individual domain and total FSFI scores were significantly correlated with FSDS-R score (P < .001). Based on domain scores, 35.5%, 18.8%, 12.8%, and 10.7% of them were at risk for orgasmic, pain, arousal, and desire problems, respectively. Arousal and lubrication problems were strongly associated with distress. Sexual problems were associated with not initiating sex (odds ratio [OR] 2.50, P = .001), often had sexual fantasy (OR 0.55, P = .036), and willingness for vaginal sex (OR 0.49, P < .001). Sexual distress was associated with having life stressors (OR 1.88, P = .012) and willingness for vaginal sex (OR 0.61, P = .003). Self-perception of body being unattractive to boyfriend (OR 3.33, P = .015), not initiating sex (OR 3.21, P = .001), willingness for vaginal sex (OR 0.39, P < .001), and no life stressors (OR 0.46, P = .036) were associated with both sexual problem and distress. CLINICAL IMPLICATIONS: Physicians should be alerted to sexual problems in young women and encourage those with distress to seek help. STRENGTHS & LIMITATIONS: Using validated psychometric tools to assess sexual problems and distress provides reference for future comparison. Admission and recall biases are unavoidable in observational questionnaire study. Depression was not evaluated and might bias the estimation of distress. CONCLUSION: About 11% of Chinese young women had sexual problems and were distressed (ie, sexual dysfunction). They were characterized by having a self-perception that their body was unattractive to their boyfriend, not initiating sex, unwilling for vaginal sex, and having life stressors. Lo SS-T, Kok W-m. Prevalence and Risk Factors for Sexual Problems and Distress in Chinese Unmarried Young Women: An Observational Study. J Sex Med 2018;15:1620-1628.


Asunto(s)
Disfunciones Sexuales Psicológicas/epidemiología , Persona Soltera , Adolescente , Adulto , Pueblo Asiatico , China/epidemiología , Femenino , Humanos , Oportunidad Relativa , Prevalencia , Factores de Riesgo , Disfunciones Sexuales Psicológicas/psicología , Encuestas y Cuestionarios , Salud de la Mujer , Adulto Joven
12.
Hum Fertil (Camb) ; 19(4): 268-274, 2016 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-27706954

RESUMEN

Infertility is estimated to affect 10-15% of couples in industrialized countries and many of them are under tremendous stress. Stress can lead to poor quality of life and sexual dysfunction in general, but little is known about their prevalence in infertile women. We, therefore, conducted this cross-sectional survey in two primary care subfertility clinics between August 2012 and April 2013. A total of 159 women completed two validated Chinese questionnaires: Female Sexual Function Index and core Fertility Quality of Life. The overall Female Sexual Function Index score (mean ± SD) of the whole group was 24.99 ± 4.22. Using the urban Chinese cut-off, the prevalence of female sexual dysfunction, low desire, arousal disorder, lubrication disorder, orgasmic disorder and sexual pain were 32.5%, 15.7%, 19.3%, 22.3%, 33.1% and 15.1%. The core Fertility Quality of Life score of the whole group was 59.76 ± 13.59 and the subgroup of infertile women with sexual dysfunction (n = 50) had significantly lower mean core Fertility Quality of Life score than those without sexual dysfunction (n = 109) (55.03 versus 61.88) (p = 0.005). Among the subscales, the relational score had the strongest correlation with sexual dysfunction. Infertile women with sexual dysfunction had significantly worse quality of life especially in the relational aspect.


Asunto(s)
Infertilidad Femenina/psicología , Calidad de Vida/psicología , Conducta Sexual/psicología , Disfunciones Sexuales Fisiológicas/psicología , Disfunciones Sexuales Psicológicas/psicología , Estrés Psicológico/psicología , Adulto , Estudios Transversales , Femenino , Hong Kong , Humanos , Persona de Mediana Edad , Adulto Joven
13.
Hong Kong Med J ; 21(6): 536-41, 2015 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-26492837

RESUMEN

OBJECTIVES: To evaluate the prevalence of osteoporosis in treatment-naïve postmenopausal women, their treatment adherence, and the risk factors for osteoporosis. DESIGN: Cross-sectional study of bone density reports, a self-administered health checklist, and computerised consultation records. SETTING: Primary care sexual and reproductive health service in Hong Kong. PARTICIPANTS: Postmenopausal Chinese women who had never received osteoporosis treatment or hormone replacement therapy. INTERVENTION: Each woman completed a checklist of risk factors for osteoporosis, menopause age, history of hormone replacement therapy, and osteoporosis treatment prior to undergoing bone mineral density measurement at the postero-anterior lumbar spine and left femur. The consultation records of those with osteoporosis were reviewed to determine their treatment adherence. MAIN OUTCOME MEASURES: T-score at the spine and hip, presence or absence of risk factors for osteoporosis, and treatment adherence. RESULTS: Between January 2008 and December 2011, 1507 densitometries were performed for eligible women; 51.6% of whom were diagnosed with osteopenia and 25.7% with osteoporosis. The mean age of women with normal bone mineral density, osteopenia, and osteoporosis was 57.0, 58.0, and 59.7 years, respectively. Approximately half of them had an inadequate dietary calcium intake, performed insufficient weight-bearing exercise, or had too little sun exposure. Logistic regression analysis revealed that age, body mass index of <18.5 kg/m(2), parental history of osteoporosis or hip fracture, and duration of menopause were significant risk factors for osteoporosis. Among those with osteoporosis, 42.9% refused treatment, 30.7% complied with treatment, and 26.3% discontinued treatment or defaulted from follow-up. Those who refused treatment were significantly older. CONCLUSIONS: Osteoporosis is prevalent in postmenopausal women. Only 50% adopted primary prevention strategies. Almost 70% refused treatment or stopped prematurely.


Asunto(s)
Densidad Ósea , Osteoporosis Posmenopáusica/etiología , Posmenopausia/fisiología , Absorciometría de Fotón , Factores de Edad , Pueblo Asiatico , Índice de Masa Corporal , Enfermedades Óseas Metabólicas/epidemiología , Enfermedades Óseas Metabólicas/etiología , Calcio de la Dieta/análisis , Estudios Transversales , Ejercicio Físico , Femenino , Fémur/fisiología , Estado de Salud , Hong Kong/epidemiología , Terapia de Reemplazo de Hormonas/psicología , Terapia de Reemplazo de Hormonas/estadística & datos numéricos , Humanos , Modelos Logísticos , Vértebras Lumbares/fisiología , Persona de Mediana Edad , Osteoporosis Posmenopáusica/tratamiento farmacológico , Osteoporosis Posmenopáusica/epidemiología , Cooperación del Paciente , Factores de Riesgo , Luz Solar , Factores de Tiempo , Negativa del Paciente al Tratamiento
14.
Hong Kong Med J ; 21(5): 462-7, 2015 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-26493078

RESUMEN

Research on medical abortion has been conducted in Hong Kong since the 1990s. It was not until 2011 that the first-trimester medical abortion service was launched. Mifepristone was registered in Hong Kong in April 2014 and all institutions that are listed in the Gazette as a provider for legal abortion can purchase mifepristone from the local provider. This article aimed to share our 3-year experience of this service with the local medical community. Our current protocol is safe and effective, and advocates 200-mg mifepristone and 400-µg sublingual misoprostol 24 to 48 hours later, followed by a second dose of 400-µg sublingual misoprostol 4 hours later if the patient does not respond. The complete abortion rate is 97.0% and ongoing pregnancy rate is 0.4%. Some minor side-effects have been reported and include diarrhoea, fever, abdominal pain, and allergy. There have been no serious adverse events such as heavy bleeding requiring transfusion, anaphylactic reaction, septicaemia, or death.


Asunto(s)
Abortivos no Esteroideos/administración & dosificación , Abortivos Esteroideos/administración & dosificación , Aborto Inducido/métodos , Mifepristona/administración & dosificación , Misoprostol/administración & dosificación , Primer Trimestre del Embarazo , Dolor Abdominal/etiología , Abortivos no Esteroideos/efectos adversos , Abortivos Esteroideos/efectos adversos , Aborto Inducido/efectos adversos , Adolescente , Adulto , Protocolos Clínicos , Diarrea/etiología , Hipersensibilidad a las Drogas/etiología , Femenino , Fiebre/etiología , Hong Kong , Humanos , Persona de Mediana Edad , Mifepristona/efectos adversos , Misoprostol/efectos adversos , Embarazo , Insuficiencia del Tratamiento , Adulto Joven
15.
Best Pract Res Clin Obstet Gynaecol ; 28(6): 835-44, 2014 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-24898437

RESUMEN

This review summarises the development of emergency contraception (EC) methods, and provides an overview on the currently available options of EC which are effective and safe back-up methods in case of non-use or failure of the regular contraception. The copper intrauterine contraceptive device is currently the most effective method. In most countries, a single dose of levonorgestrel 1.5 mg is the first-line hormonal EC given within 72 h of unprotected intercourse. The oral anti-progestogens such as mifepristone and ulipristal acetate are promising alternatives with better efficacies and a wider treatment window of up to 120 h post coitus, probably resulting from more diverse ancillary mechanisms of actions. Education on EC should be part of any contraceptive counselling. Improving access to EC by providing it over the counter or in advance would not promote its abuse nor encourage risky sexual behaviours, but may further facilitate the timely use so as to achieve the best efficacy.


Asunto(s)
Anticoncepción Postcoital , Anticonceptivos Femeninos/administración & dosificación , Dispositivos Intrauterinos de Cobre , Levonorgestrel/administración & dosificación , Anticoncepción Postcoital/instrumentación , Anticoncepción Postcoital/métodos , Anticonceptivos Sintéticos Orales/administración & dosificación , Esquema de Medicación , Femenino , Conocimientos, Actitudes y Práctica en Salud , Humanos , Mifepristona/administración & dosificación , Norpregnadienos/administración & dosificación , Factores de Tiempo
16.
J Sex Med ; 11(7): 1749-56, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-24655732

RESUMEN

INTRODUCTION: As sexual medicine evolves, much advancement has been achieved in understanding male sexuality and treating male sexual dysfunction. Less is known about female sexual pattern, the prevalence of sexual problems, and their correlation with confounding factors. AIM: To enhance our understanding of female sexuality and the risk factors that contributed to sexual problems in reproductive age women. METHOD: A cross-sectional survey was conducted in family planning and prepregnancy checkup clinics from December 2007 to December 2009, with 2,146 sexually active Chinese women aged 21 to 40 years completed the entire questionnaire. MAIN OUTCOME MEASURES: Prevalence of sexual symptoms, coital frequency, and other sexual behavior-related activities were measured. RESULTS: Overall, 59.0% of respondents had at least one sexual problem. In this sample, 31.8% of respondents reported no desire; 31.7% had arousal problems; 40% had anorgasmia, and 33.8% experienced coital pain for at least 3 months within the past 1 year. Chi-square test showed significant correlation among the four types of sexual problems(P < 0.001). Univariate regression model showed that all sexual symptoms were significantly correlated with unidirectional coitus initiation, low coital frequency, and low foreplay enjoyment. Loglinear model revealed that desire, arousal, and orgasmic problems were correlated with low foreplay enjoyment. Arousal problem was correlated with high acceptance toward pornography and history of medical disease. Coital pain was correlated with secondary education and planning to have more children. Both unidirectional coitus initiation and low coital frequency were major contributors to all four sexual symptoms. CONCLUSIONS: Sexual problem is a prevalent health issue among reproductive age women. A number of risk factors are identified, which provide useful direction to the design of counseling and education materials that might help to enhance sexual performance in women.


Asunto(s)
Conducta Sexual/etnología , Disfunciones Sexuales Psicológicas/etnología , Adulto , Nivel de Alerta/fisiología , Pueblo Asiatico/etnología , Distribución de Chi-Cuadrado , Coito , Estudios Transversales , Femenino , Hong Kong/epidemiología , Humanos , Prevalencia , Factores de Riesgo , Conducta Sexual/psicología , Disfunciones Sexuales Psicológicas/psicología , Sexualidad/etnología , Sexualidad/psicología , Encuestas y Cuestionarios , Adulto Joven
17.
Maturitas ; 74(2): 190-5, 2013 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-23265305

RESUMEN

OBJECTIVE: To study the sexual activities and prevalence of sexual dysfunctions in midlife Chinese women and their correlations with demographic factors, sexual dissatisfaction and interpersonal difficulty. STUDY DESIGN: This is a cross-sectional survey of a convenience sample of women aged 40-60, who requested gynecological checkup or attend social activities at Women's Club. MAIN OUTCOME MEASURES: Sexual activities, sexual dysfunctions, sexual dissatisfaction, demographic factors and interpersonal difficulty were assessed by self-administered questionnaire. RESULTS: Among 371 eligible subjects, 22.4% and 39.6% women had low intimacy and coitus frequency (0 to <12 acts in one year), respectively. The odds ratios for low coital frequency in the natural menopausal and surgical menopausal subgroups were 3.00 and 5.09, respectively (95% confidence interval: 1.73-5.19 and 1.77-14.69, respectively). Overall, 77.2% women had at least one type of sexual dysfunctions; this proportion was highest in the surgically menopausal subgroup (88.9%) followed by the naturally menopausal subgroup (79.3%), the perimenopausal subgroup (78.2%) and the premenopausal subgroup (72.2%) (p=0.003). No lubrication (42.9%) was the commonest sexual dysfunction and predominantly affected naturally and surgically menopaused women (p=0.001). Sexual dysfunction was the major contributor to sexual dissatisfaction (0.80), followed by interpersonal difficulty (0.2). Arousal disorder was the pivot of interaction between sexual dissatisfaction, menopausal status and low coital frequency. CONCLUSIONS: Chinese women had fewer intimate contacts and less coitus when menopause progressed. No lubrication was the commonest sexual dysfunction and predominantly affected menopaused women. Our model showed that sexual dysfunction is the main contributor to sexual dissatisfaction.


Asunto(s)
Pueblo Asiatico , Perimenopausia/psicología , Posmenopausia/psicología , Premenopausia/psicología , Conducta Sexual/fisiología , Conducta Sexual/psicología , Adulto , Nivel de Alerta , China , Intervalos de Confianza , Estudios Transversales , Femenino , Humanos , Relaciones Interpersonales , Libido , Persona de Mediana Edad , Oportunidad Relativa , Perimenopausia/fisiología , Satisfacción Personal , Posmenopausia/fisiología , Premenopausia/fisiología , Disfunciones Sexuales Fisiológicas/fisiopatología , Disfunciones Sexuales Fisiológicas/psicología , Disfunciones Sexuales Psicológicas/psicología
18.
Hong Kong Med J ; 18(4): 299-303, 2012 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-22865173

RESUMEN

OBJECTIVES. To review the profile of emergency contraceptive users, their reasons for using emergency contraception, and whether they use it correctly. DESIGN. Retrospective analysis of medical records. SETTING. Six Birth Control Clinics and three Youth Health Care Centres of the Family Planning Association of Hong Kong. PARTICIPANTS. Women requesting emergency contraception between 2006 and 2008. MAIN OUTCOME MEASURES. Demographics of emergency contraception users, reasons for requesting emergency contraception, number of times the subject had unprotected intercourse before emergency contraception use, type of emergency contraception provided, coitus-treatment intervals, and outcomes. RESULTS. A total of 11 014 courses of emergency contraception were provided, which included 10 845 courses of levonorgestrel-only pills, 168 intrauterine contraceptive devices, and one course of pills plus an intrauterine contraceptive device. The mean age of the users was 30 years. Two thirds (65.6%) were nulliparous and 64.9% had not had a previous abortion. Their major reasons for requesting emergency contraception were: omission of contraceptive at the index intercourse (38.9%), condom accidents (38.0%), and non-use of any regular contraceptives (20.6%). Non-users of contraceptives were more likely to have had a previous abortion. In all, 97.9% of women took emergency contraception within 72 hours of their unprotected intercourse; 98% had had a single act of unprotected intercourse. None of the intrauterine contraceptive device users became pregnant. The failure rate for emergency contraceptive pills was 1.8%. CONCLUSIONS. Women requested emergency contraception because contraceptives were omitted or condom accidents. Health care providers should focus on motivating women with a history of abortion to use contraceptives, and ensure that condom users know how to use them correctly. Most women followed instructions on the use for emergency contraception and their outcomes were satisfactory.


Asunto(s)
Anticoncepción Postcoital , Servicios de Planificación Familiar , Adolescente , Adulto , Condones , Femenino , Humanos , Dispositivos Intrauterinos , Persona de Mediana Edad , Estudios Retrospectivos
19.
Int J Gynaecol Obstet ; 118(3): 223-6, 2012 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-22727056

RESUMEN

OBJECTIVE: To determine whether women use emergency contraception (EC) repeatedly instead of regular contraception methods if they have access to EC. METHODS: Data from the records of 9201 women who underwent EC 11014 times in the years 2006 through 2008 at Hong Kong clinics were retrospectively analyzed. The χ(2) test was used to look for associations between demographic characteristics and repeated EC use and the Wilcoxon signed rank test was used to compare the significance of changes in contraceptive use over time. RESULTS: A total of 10845 courses of EC pills and 168 intrauterine devices were provided to the 9201 women, 89.4% of whom used EC once and 8.5% twice within a year. Using EC more than twice was only associated with unstable relationships. The percentages of women using no contraceptives during intercourse decreased from 20.6% at baseline to 4.7% four to 6 weeks after EC, 4.0% at 6 months, and 3.4% at 12 months. The percentages of women using highly effective methods of contraception increased from 3.5% to 20.8%, 27.3%, and 27.7% at the same time points. CONCLUSION: The low rate of repeated EC use and the positive changes in contraceptive choice after EC are reassuring.


Asunto(s)
Conducta de Elección , Conducta Anticonceptiva/psicología , Anticoncepción Postcoital/psicología , Adulto , Estudios Transversales , Femenino , Hong Kong , Humanos , Dispositivos Intrauterinos , Adulto Joven
20.
Int J Gynaecol Obstet ; 116(1): 52-6, 2012 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-22036061

RESUMEN

OBJECTIVE: To assess knowledge and stigmatizing attitudes related to human papillomavirus (HPV) and HPV testing among Chinese healthcare providers in Hong Kong. METHODS: Between May and September 2010, an anonymous self-administered questionnaire was sent to 247 doctors, nurses, and smear-taking trainees providing cervical screening in Hong Kong. RESULTS: In total, 137 questionnaires were returned. Most participants had basic knowledge about HPV infection and HPV vaccination. Only about 33% knew that high-risk HPV does not cause genital warts, infection is most common among young women, or infected individuals might not have any identifiable sexual risk factors. Regarding HPV testing, 6 of 7 knowledge items were answered incorrectly by many participants (≥ 50%), highlighting a lack of understanding of the indications for HPV testing and the implications of a positive result. About 30% of participants agreed that individuals with HPV infection were sexually easy, responsible for their infection, or had more than 1 sexual partner. More knowledge about HPV infection predicted less stigmatizing attitudes. CONCLUSION: Continued education on HPV and HPV testing is needed for frontline healthcare providers of screening in Hong Kong. The stigmatizing attitudes toward HPV-infected individuals warrant further exploration of the impact of HPV infection on patient care and interventions.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Personal de Salud , Infecciones por Papillomavirus/prevención & control , Infecciones por Papillomavirus/psicología , Estigma Social , Displasia del Cuello del Útero/prevención & control , Displasia del Cuello del Útero/psicología , Adulto , Anciano , Pueblo Asiatico , Femenino , Hong Kong , Humanos , Persona de Mediana Edad , Vacunas contra Papillomavirus/administración & dosificación , Conducta Sexual , Encuestas y Cuestionarios , Frotis Vaginal , Adulto Joven
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