EPIDEMIOLOGICAL DATA ON THE DETECTION OF IMMUNOGLOBULINS OF CLASS IGM, IGG TO SARS-COV-2 AMONG POPULATION OF POLTAVA REGION.

OBJECTIVE: The aim: Of this study was to analyze epidemiological data on the detection of immunoglobulins of class M and G (IgM, IgG) to SARS-CoV-2 among urban and rural population of Poltava region. PATIENTS AND METHODS: Materials and methods: We have analyzed the research results of 2841 patients to determine IgM and IgG levels to SARS-CoV-2. The study included the results of patients in Poltava and nearby villages of Poltava region, obtained during July - December 2020. RESULTS: Results: Thus, 84% of patients applied for detection of IgM in the serum of patients with the pathogen COVID-2019. We have found only 135 positive results for the detection of IgM to SARS-CoV-2, which was 5.7% of the total number of people who underwent this study from July to December 2020. Moreover, women received a positive result more often than men. The IP samples for the detection of IgM to SARS-CoV-2 in the serum of patients averaged 2.5 ± 1.04. It was found that patients went to the laboratory to detect IgG to SARS-CoV-2 with the vast majority among them were residents of Poltava. However, in this case the share of positive results was 47.7%, among which the female population outnumbered the male. CONCLUSION: Conclusions: The frequency of detection of positive results on IgM to SARS-CoV-2 is about 6%. The share of positive results on IgG to SARS-CoV-2 was 47.7%, among them 76.2% were women. The frequency of detection of IgM and IgG to SARS-CoV-2 during October-December 2020 significantly exceeds the indices in July-September of the same year.

COMPLEX THERAPY OF ATOPIC CHEILITIS.

OBJECTIVE: The aim: Was to evaluate clinical data after the use of pimecrolimus (1% cream "Elidel") in patients with mild and moderate severity of atopic cheilitis, according to modern therapeutic requirements. There was an algorithm of treatment the patients with cheilitis proposed it based on the data from literary sources and personal clinical experience. PATIENTS AND METHODS: Materials and methods: 22 patients with atopic cheilitis aged from 19 to 40 agreed on a clinical examination in accordance with the protocol of the study. Patients were prescribed "Elidel" in the form of 1% cream for lubrication of the affected areas of the skin and lips, and antihistamine "Erius", for the normalization of the general condition used sedatives and vitamins after consultation of specialists in the general profile. RESULTS: Results: Patients of both groups during the re-examination after 3, 7, 10 days recorded a positive dynamics of the red border of the lips and skin: a significant reduction in the inflammatory process, normalization of indicators of general blood analysis, improvement in the overall quality of life of patients. CONCLUSION: Conclusions: The results of treatment allow to consider 1% cream "Elidel" (pimecrolimus) as a preparation of choice in the complex treatment of patients with atopic cheilitis of mild and moderate severity.