Relationship between Components, Intestinal Microbiota, and Mechanism of Hypoglycemic Effect of the Saggy Ink Cap Medicinal Mushroom (Coprinus Comatus, Agaricomycetes): A Review.

Coprinus comatus is rich in a variety of nutrients, which has been reported to display a good hypoglycemic effect. However, there is no consensus on the hypoglycemic mechanism of this mushroom. Intestinal microbiota, a complex and intrinsic system, is closely related to metabolism. In this review, we discussed the potential relationship between certain components of C. comatus and intestinal microbiota to illustrate the possible hypoglycemic mechanism of C. comatus through intestinal microbiota. It will provide a new perspective for the study of hypoglycemic mechanism of C. comatus and promote the development and utilization of this mushroom.

A review: structure-activity relationship between saponins and cellular immunity.

Saponins, which exhibit many different biological and pharmacological activities, are present in a wide range of plant species and in some marine organisms. Notably, the researchers have found that saponins can activate the immune system in mammals. The strength of this function is closely related to the chemical structure of saponins. The present study of the structure-activity relationship suggests that aglycones, glycochains on aglycones and special functional groups of saponins affect the immune activity of saponins. This paper reviews the effects of different saponins on cellular immunity. As well as the structure-activity relationship of saponins. It is hoped that the information integrated in this paper will provide readers with information on the effects of saponins on cellular immunity and promote the further study of these compounds.

Application and mechanism of probiotics in skin care: A review.

BACKGROUND: Skin problems have been the focus of attention in recent years. Skin aging, wrinkles, pigmentation, dryness has been a problem that makes people feel troubled. Researchers have been devoted to find ways to solve these skin problems. Micro-ecological skin care is a popular concept these days, and improving skin health through the use of probiotics is a hot topic of discussion. OBJECTIVE: Many experimental studies have shown that probiotics have a good effect on improving skin problems. This paper aims to comprehensively review the application and mechanism of probiotics in skin care and provide theoretical basis for the application of probiotics in skin care. METHODS: Literatures in this review were searched in PubMed, China National Knowledge Infrastructure (CNKI), Web of Science, and Science Direct. RESULTS: Probiotics have potent effects on skin whitening, moisturizing, anti-aging, anti-wrinkle and removing body odor. CONCLUSIONS: The effects of probiotics on skin whitening, skin moisturizing, anti-aging, improving skin wrinkles and removing body odor were reviewed, which provided a new basis for the extensive application of probiotics in skin care.