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1.
Infect Dis Model ; 7(1): 45-61, 2022 Mar.
Article En | MEDLINE | ID: mdl-34869961

This work examines a mathematical model of COVID-19 among two subgroups: low-risk and high-risk populations with two preventive measures; non-pharmaceutical interventions including wearing masks, maintaining social distance, and washing hands regularly by the low-risk group. In addition to the interventions mentioned above, high-risk individuals must take extra precaution measures, including telework, avoiding social gathering or public places, etc. to reduce the transmission. Those with underlying chronic diseases and the elderly (ages 60 and above) were classified as high-risk individuals and the rest as low-risk individuals. The parameter values used in this study were estimated using the available data from the Johns Hopkins University on COVID-19 for Brazil and South Africa. We evaluated the effective reproduction number for the two countries and observed how the various parameters affected the effective reproduction number. We also performed numerical simulations and analysis of the model. Susceptible and infectious populations for both low-risk and high-risk individuals were studied in detail. Results were displayed in both graphical and table forms to show the dynamics of each country being studied. We observed that non-pharmaceutical interventions by high-risk individuals significantly reduce infections among only high-risk individuals. In contrast, non-pharmaceutical interventions by low-risk individuals have a significant reduction in infections in both subgroups. Therefore, low-risk individuals' preventive actions have a considerable effect on reducing infections, even among high-risk individuals.

2.
Springerplus ; 5: 455, 2016.
Article En | MEDLINE | ID: mdl-27119059

The paper presents a significant improvement to the implementation of the spectral relaxation method (SRM) for solving nonlinear partial differential equations that arise in the modelling of fluid flow problems. Previously the SRM utilized the spectral method to discretize derivatives in space and finite differences to discretize in time. In this work we seek to improve the performance of the SRM by applying the spectral method to discretize derivatives in both space and time variables. The new approach combines the relaxation scheme of the SRM, bivariate Lagrange interpolation as well as the Chebyshev spectral collocation method. The technique is tested on a system of four nonlinear partial differential equations that model unsteady three-dimensional magneto-hydrodynamic flow and mass transfer in a porous medium. Computed solutions are compared with previously published results obtained using the SRM, the spectral quasilinearization method and the Keller-box method. There is clear evidence that the new approach produces results that as good as, if not better than published results determined using the other methods. The main advantage of the new approach is that it offers better accuracy on coarser grids which significantly improves the computational speed of the method. The technique also leads to faster convergence to the required solution.

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