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1.
Cureus ; 14(8): e27731, 2022 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-36106256

RESUMEN

Congenital malaria is the direct infection of an infant with a malarial parasite from the mother either during pregnancy or at birth. Neonatal malaria occurs due to an infective mosquito bite after birth. Neonatal and congenital malaria (NCM) can occasionally present with life-threatening neonatal sepsis and rarely with neonatal jaundice. These conditions are typically managed by general pediatricians, especially in remote areas without access to specialized care. A high clinical index of suspicion is required to diagnose neonatal and congenital malaria, given that their presentation can mimic other more common neonatal conditions. We present two neonates with malaria, highlighting the importance of considering this treatable entity in the differential.

2.
Mycoses ; 59(12): 757-759, 2016 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-27402206

RESUMEN

Fungal keratitis due to Schizophyllum commune is very rare. In this study, we report the clinical and microbiological profile of five patients with fungal keratitis due to S. commune. Direct microscopic examination of corneal scrapings from all five patients showed septate branching hyaline fungal filaments. Similarly, in all five patients Sabouraud dextrose agar (SDA) plates inoculated with corneal scrapings showed white, cottony colonies on the second day of incubation. Lactophenol cotton blue stained wet preparation of 7-day-old colonies on SDA revealed clamp connections and no spores. The fungus was identified by its characteristic clamp connections, fan-shaped bracket fruiting body with pinkish-grey longitudinally split-radiating gills. The phenotypic identification of one of the five isolates further conformed by ITS sequencing. Treatment outcome was available for two of the five patients; in these two patients, the keratitis resolved with topical natamycin.


Asunto(s)
Infecciones Fúngicas del Ojo/microbiología , Queratitis/microbiología , Schizophyllum/aislamiento & purificación , Adulto , Antifúngicos/administración & dosificación , Córnea/microbiología , Infecciones Fúngicas del Ojo/tratamiento farmacológico , Femenino , Humanos , Queratitis/tratamiento farmacológico , Masculino , Persona de Mediana Edad , Natamicina/administración & dosificación , Estudios Retrospectivos , Schizophyllum/efectos de los fármacos , Schizophyllum/genética , Schizophyllum/fisiología
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