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1.
J Environ Manage ; 361: 121244, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38815430

RESUMEN

Build-up/wash-off models were originally developed for small-scale laboratory facilities with uniform properties. The effective translation of these models to catchment scale necessitates the meticulous calibration of model parameters. The present study combines the Mat-SWMM tool with a genetic algorithm (GA) to improve the calibration of build-up and wash-off parameters. For this purpose, Mat-SWMM was modified to equip it with the capacity to provide comprehensive water quality analysis outcomes. Additionally, this research also conducts a comparative examination of two distinct types of objective functions in the optimization. Rather than depending on previous literature, this study undertook a numerical campaign to ascertain an appropriate range for the relevant parameters within the case study, thereby ensuring the optimization algorithm's efficient functionality. This research also implements an integrated event calibration approach, i.e., a novel method that calibrates all rainfall events collectively, thus improving systemic interaction representation and model robustness. The findings indicate that employing this methodology significantly enhances the reliability of the outcomes, thereby establishing a more robust procedure. The first objective function (TSS instantaneous less squared difference function, OF 1), which is widely employed in the literature, was designed to minimize the difference between observed and predicted instantaneous Total Suspended Solids (TSS) concentrations. In contrast, the second function (mass and mass peak consistency function, OF 2) considers integral model outputs, i.e., the overall mass balance, the time of the peak mass flow rate, and its intensity. The analysis of the outputs revealed that both objective functions demonstrated sufficient performance. OF 1 provided slightly better performance in predicting the TSS concentrations, whereas OF 2 demonstrated superior ability in capturing global event characteristics. Notably, the optimal parameter set identified through OF 2 aligned with the physically plausible ranges traditionally recommended in technical manuals for urban catchments. In contrast, OF 1's optimal set necessitated an expansion in the acceptable parameter ranges. Finally, from a computational burden viewpoint, OF 1 demanded a significantly higher number of function evaluations, thus implying an escalating computational cost as the range expands. Conversely, OF 2 necessitated fewer evaluations to converge toward the optimal solution.


Asunto(s)
Algoritmos , Modelos Teóricos , Lluvia , Calidad del Agua , Monitoreo del Ambiente/métodos
2.
Med Eng Phys ; 77: 19-30, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-32008936

RESUMEN

The paper discusses a Smoothed Particle Hydrodynamics (SPH) model for the analysis of the multiphase flow occurring in an experimental microfluidic device for conformal coating of pancreatic islets with a biocompatible and permeable polymer. The proposed numerical model, based on a weakly-compressible SPH approach, accurately mimics the encapsulation process while assuring phase conservation, thus overcoming potential limitations of grid-based models. The proposed SPH model is a triphasic multi-phase model that allows one: (i) to reproduce the physics of islet conformal coating, including the effects of surface tension at the interface of the involved fluids and of the islet diameter; and (ii) to evaluate how modulation of process parameters influences the fluid dynamics within the microfluidic device and the resulting coating characteristics. This model can represent a valuable, time- and cost-effective tool for the definition of optimized encapsulation conditions through in silico screening of novel combinations of conformal coating parameters, including polymeric coating blends, size range of insulin-secreting cell clusters, utilized chemical reagents, device geometry and scale.


Asunto(s)
Hidrodinámica , Islotes Pancreáticos , Dispositivos Laboratorio en un Chip , Modelos Teóricos , Tensión Superficial , Factores de Tiempo
3.
J Environ Manage ; 246: 418-425, 2019 Sep 15.
Artículo en Inglés | MEDLINE | ID: mdl-31200176

RESUMEN

This paper studies in depth the first flush concept with the aim of exploiting the potential of this phenomenon for an effective and economical implementation of stormwater quality control practices. A quantitative first flush methodology recently proposed in the scientific literature is applied to discrete water quality data of different pollution parameters from an Italian database. The methodology is rigorous and effective for characterising the dynamics of different pollutant types in wet-weather runoff, allowing an assessment of the first flush strength and the detection of the runoff volume required to reduce concentrations to background levels peculiar of the catchment. A strong reduction in concentration is attained after 3 mm runoff, but the achievement of background levels for all pollutant parameters requires the transit of 6 mm runoff. Sensitivity analysis shows the crucial role of the event selection criteria for enhancing the robustness of the methodology. The advantages of the adopted procedure are also highlighted by comparison with the widely used Mass First Flush Ratio method. The results are also compared with Italian guidelines for the design of stormwater quality control measures, pointing out the fruitfulness and profitability of the methodology for decision making in this context.


Asunto(s)
Lluvia , Contaminantes del Agua , Monitoreo del Ambiente , Movimientos del Agua , Tiempo (Meteorología)
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